Background: Normal pregnancy and the postpartum period are characterized by thrombotic predisposition. Consequently, monitoring coagulation markers conducting risk assessments essential in preventing events that negatively impact both mother child. In medical practice, fibrinogen/fibrin degradation products (FDPs) main currently investigated pregnancy. Methods: We proteins C S, antiphospholipid antibodies (APLs), human factor V, beta-2-glycoprotein 1 or apolipoprotein H (APOH) levels to...

This study evaluated the differential expression of four placental markers—vitamin D receptor (VDR), Cluster Differentiation 44 (CD44), osteopontin (OPN), and cyclooxygenase-2 (COX-2)—in response to pathogens, which may contribute our understanding pathogen-specific impacts on pregnancy outcomes. We immunohistochemically (IHC) analyzed tissues obtained from 70 healthy-term pregnant women in control group compared them 78 with above 24 weeks gestation, single-pathogen vaginal infection,...

Background: Despite being a very well-documented subject in the literature, there are still conflicting results regarding teenage pregnancies and their fetal outcomes. Methods: We conducted retrospective, comparative cohort study that included 1082 mothers aged less than 18 years, compared to 41,998 over who delivered our tertiary referral center between January 2015 December 2021. To check for significant differences two groups, chi-qquared or Fisher’s test categorical variables were used....

Background: The most commonly known cardiac effect of gestational diabetes mellitus (GD) in the fetus is hypertrophic cardiomyopathy, but recent studies show that it preceded by subclinical dysfunction. This study aimed to assess GD on fetal geometry and contractility two-dimensional speckle-tracking technology. Methods: We performed a prospective observational included 33 pregnant patients with 30 healthy individuals. For all fetuses, four-chamber 3 s cine-loop was recorded analyzed Fetal...

Chorioamnionitis or intra-amniotic infection is an that affects the intrauterine content during pregnancy. Numerous studies have reported vaginal colonization with various types of infectious agents as a risk factor for chorioamnionitis. Although this complication occurs due to ascending polymicrobial bacterial at time membrane breakage, it may also occur in pregnant women intact membranes, mainly Ureaplasma urealyticum (U. urealyticum) and Mycoplasma hominis (M. hominis). The main aim...

(1) Background: In the context of COVID-19 pandemic, educational system in Romania faced major challenges. Online knowledge development was necessary and mandatory during this time; (2) Methods: our study included a group 140 preadolescents used phenomenology qualitative method to investigate if novel online teaching, implemented hurry pandemic without any previous teacher training, managed replace face-to-face teaching; (3) Results: The students have expressed their joy for courses, as long...

The purpose of this study was to evaluate the association between follicle-stimulating hormone (FSH) receptor (c.-29G>A) and FSH beta chain (c.-280G>T) polymorphisms endometriosis in Romanian women.We performed polymorphic analysis gene 44 patients with 34 controls. Genomic DNA obtained from peripheral blood were investigated using restriction fragment length polymorphism (RFLP).There no significant differences genotype frequencies For heterozygous type we did not find a difference its...

Cervical cancer is rare in adolescent and pediatric populations, with adenocarcinoma being the most commonly reported. Clear cell of uterine cervix accounts for only 4% all cases, about two-thirds are associated intrauterine diethylstilbestrol (DES) exposure. We report case a 14-year-old virgin girl who presented 1-month-long history abnormal vaginal bleeding lower abdominal pain. Transabdominal pelvic ultrasound examination revealed presence an irregular, homogeneous cervical mass that was...

Endometriosis (EM) is a chronic multifactorial disease characterized by the presence of endometrial tissue outside uterus. The clear etiopathogenesis EM unclear. Increasing evidence was gathered about crucial involvement gut microbiota in early stages disease, and its progression.

Endometriosis, an intriguing gynecological illness, poses a substantial health concern for women of reproductive age, despite its widespread occurrence and limited comprehension. The objective this study is to assess the diagnostic precision transvaginal sonography (TVS) pelvic magnetic resonance imaging (MRI) identification deep infiltrated endometriosis (DIE). This encompassed cohort 256 patients exhibiting signs symptoms endometriosis, with aim assessing accuracy over span four years....

A major myomectomy-associated problem is excessive blood loss. The aim of the present study was to evaluate effect glypressin on loss during laparoscopic myomectomy (LM) in women with uterine myomas. total 188 scheduled for LM myomas were divided into two groups. one group (n=64) received a 5-ml intramyometrial injection 0.2 mg/ml (glypressin group; 1). other (n=124) (group 2) had an performed without any method reduce decrease postoperative hemoglobin (Hb), hematocrit (Ht), morbidity and...

A common problem in gynecological practice is the differential diagnosis of ovarian masses. The clinician must apply IOTA (International Ovarian Tumor Analysis) ADNEX (Assessment Different Neoplasia Adnexa) model criteria to evaluate risk benign, borderline or malignant tumors. aim this study was verify if a practical tool be used before surgery and there significant difference between histological findings. prospective single center performed January 2017 December 2019 Obstetrics Gynecology...

Endometriosis, one of the most common gynecologic pathologies, is defined as an inflammatory, estrogen-dependent disease characterized by growth endometrial stroma and glands outside uterine cavity. It a multifactorial disease, conditioned genetic immune factors triggered hormonal environmental factors. Estrogen receptors (ER) progesterone (PR) expression significantly modified in endometriotic tissue, compared to normal endometrium. We performed prospective study that included 16 patients...

Background and Objectives: Although frequent associated with high mortality morbidity rate, congenital heart disease (CHD) has a suboptimal prenatal detection significant variation according to the scanning protocol. The aim of this study was evaluate role 3-vessels trachea view (3VT) in detecting CHD, or without use Color Doppler, an emphasis on major CHD. Materials Methods: We performed retrospective 1596 unselected pregnant patients presenting at 11-37 weeks gestation for routine anomaly...

(1) Background: The three factors within the Virchow triad play leading role in development of deep vein thrombosis (DVT) during pregnancy. (2) Methods: This research approaches various risk associated with DVT and its most representative complications, pulmonary thromboembolism cerebral venous thrombosis, pregnant postpartum women across a 15-year period (2007–2021). (3) Results: A total 201 out 287 patients had factors, while 86 did not present any. Out 47 developed thromboembolism, 12...

: We investigated the expression of inflammation, placental development, and function markers, including cluster differentiation 44 (CD44), osteopontin (OPN), cyclooxygenase-2 (COX-2), to shed light on controversy regarding impact COVID-19 epidemic fetal development pregnancy outcomes.

The trophoblast is a significant source of vitamin D synthesis during pregnancy, with the literature suggesting its role in fetal growth. We aim to underline possible mechanism that would explain negative outcomes COVID-19-positive mothers by examining relationship between altered placental structure and function throphoblast cells' receptor levels.

(1) Background: Our study aimed to examine tissue expression of CD44, vitamin D receptor (VDR), and cyclooxygenase 2 (COX-2) in endometriosis-affected women with without progestin treatment inquire about their implications the pathogenesis endometriosis. (2) Methods: A cohort 60 diagnosed endometriosis was divided into two groups, which 26 received 34 treatment. We conducted an immunohistochemical (IHC) analysis paraffin-embedded samples collected post surgery. The primary goal elucidate...