- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Congenital Heart Disease Studies
- Biomarkers in Disease Mechanisms
- Ectopic Pregnancy Diagnosis and Management
- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Cardiovascular Issues in Pregnancy
- Maternal and fetal healthcare
- Pediatric Urology and Nephrology Studies
- Pelvic floor disorders treatments
- Gynecological conditions and treatments
- Assisted Reproductive Technology and Twin Pregnancy
- Sepsis Diagnosis and Treatment
- Tracheal and airway disorders
- Neonatal and Maternal Infections
- Congenital Anomalies and Fetal Surgery
- COVID-19 Impact on Reproduction
- Reproductive Biology and Fertility
- Urinary Tract Infections Management
- Prenatal Screening and Diagnostics
- Hemoglobinopathies and Related Disorders
- Pregnancy and Medication Impact
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Grigore T. Popa University of Medicine and Pharmacy
2015-2024
Clinical Emergency Hospital Bucharest
2020
(1) Background: The identification of patients at risk for hepatitis B and C viral infection is a challenge the clinicians public health specialists. aim this study was to evaluate compare predictive performances four machine learning-based models prediction HBV HCV status. (2) Methods: This prospective cohort screening evaluated adults from North-Eastern South-Eastern regions Romania between January 2022 November who underwent in their family physician’s offices. patients’ clinical...
(1) Background: Prenatal care providers face a continuous challenge in screening for intrauterine growth restriction (IUGR) and preeclampsia (PE). In this study, we aimed to assess compare the predictive accuracy of four machine learning algorithms predicting occurrence PE, IUGR, their associations group singleton pregnancies; (2) Methods: This observational prospective study included 210 pregnancies that underwent first trimester screenings at our institution. We computed performance...
(1) Background: SARS-CoV-2 infection during pregnancy could determine important maternal and fetal complications. We aimed to prospectively assess placental immunohistochemical changes, immunophenotyping alterations, outcomes in a cohort of patients with COVID-19; (2) Methods: 52 pregnant admitted tertiary maternity center between October 2020 November 2021 were segregated into two equal groups, depending on the presence infection. Blood samples, fragments umbilical cord, amniotic membranes,...
Background: The most commonly known cardiac effect of gestational diabetes mellitus (GD) in the fetus is hypertrophic cardiomyopathy, but recent studies show that it preceded by subclinical dysfunction. This study aimed to assess GD on fetal geometry and contractility two-dimensional speckle-tracking technology. Methods: We performed a prospective observational included 33 pregnant patients with 30 healthy individuals. For all fetuses, four-chamber 3 s cine-loop was recorded analyzed Fetal...
(1) Background: Recurrent pregnancy loss (RPL) and recurrent implantation failure (RIF) have in common a deficient maternal adaptation to the semi-allogeneic fetus, which killer immunoglobulin-like receptor (KIR) family expressed by natural (NK) cells play an important role. The aim of this study was evaluate influence KIR haplotype on reproductive outcomes after single embryo transfer IVF cycles patients with RPL RIF. (2) Methods: Patients RIF who presented at Origyn Fertility Center from...
(1) Background: Neonatal early-onset sepsis (EOS) is associated with important mortality and morbidity. The aims of this study were to evaluate the association between serum hematological biomarkers early onset neonatal in a cohort patients prolonged rupture membranes (PROM) calculate their diagnostic accuracy. (2) Methods: A retrospective was conducted on 1355 newborns PROM admitted January 2017 March 2020, who divided into two groups: group A, ≥ 18 h, B, ROM < h. Both groups further...
(1) Background: Urinary tract infections (UTIs) are an important cause of perinatal and maternal morbidity mortality. The aim this study was to describe compare the main pregnancy outcomes among pregnant patients with complicated uncomplicated UTIs; (2) Methods: This retrospective included 183 who were evaluated for UTIs urosepsis in Urology Department ‘C.I. Parhon’ University Hospital, followed up at a tertiary maternity hospital- ‘Cuza-voda’ from Romania between January 2014 October 2023....
(1) Background: Pregnant patients with severe forms of coronavirus disease 2019 (COVID-19) can experience adverse pregnancy outcomes. The aim this study was to retrospectively assess the risk factors associated admission intensive care unit (ICU) pregnant COVID-19, as well outcomes these patients; (2) Methods: Medical records 31 COVID-19 admitted three clinical hospitals from Romania, between October 2020 and November 2021 were examined. segregated into two groups depending on their...
Abstract Background There is no clear consensus on the management of caesarean scar pregnancy (CSP), a complex and life-threatening condition. The objective this study was to present novel approach CSP that combines medical therapy multidose methotrexate mifepristone with active surgical by uterine curettage consecutive local haemostasis. Case presentation We report prospective case series six women first trimester pregnancy, in whom diagnosis confirmed 2D color Doppler transvaginal...
Background and Objectives: Urinary tract infections (UTIs) are an important cause of perinatal maternal morbidity mortality. The aim this study was to describe compare the main pregnancy outcomes among pregnant patients with complicated uncomplicated UTIs; Materials Methods: This retrospective included 183 who were evaluated for UTIs urosepsis in Urology Department ‘C.I. Parhon’ University Hospital, followed up at a tertiary maternity hospital—‘Cuza-voda’ from Romania between January 2014...
Because of its histological and embryological complex development, the ovary can be source a large variety tumors, ovarian cancer being fifth female neoplasia as frequency. A major clinical significance is that tumor asymptomatic for long period time.Ovarian proliferative pathology raises number important issues from both theoretical practical point view. The change in therapeutic attitude, especially areas surgery chemotherapy, has led last decades to an improvement survival rate. Our...
Abstract Aim : The aim of this study is to identify correlations between total antioxidant status values mothers and their infants compare these in accordance the presence or absence intrauterine growth restriction. Material methods This a prospective, comparative performed over period 3 years on number 52 mothers. Thirty-six them had restriction 16 were appropriate for gestational age used purposes. General information regarding mother, infant pregnancy recorded. In addition, was assessed...
Endometriosis (EMS) is a benign condition characterized by systemic inflammation that affects fertile women at reproductive age. Ultrasound became, in recent years, the method of choice for both effective diagnostic and preoperative planning. Therefore, accurate characterization mapping endometriotic lesions imperative such circumstances to enable optimal approach treatment, whether surgical or non-surgical based on severity findings. This pictorial essay outlines practical evaluating...
Background and Objectives: Although frequent associated with high mortality morbidity rate, congenital heart disease (CHD) has a suboptimal prenatal detection significant variation according to the scanning protocol. The aim of this study was evaluate role 3-vessels trachea view (3VT) in detecting CHD, or without use Color Doppler, an emphasis on major CHD. Materials Methods: We performed retrospective 1596 unselected pregnant patients presenting at 11-37 weeks gestation for routine anomaly...
(1) Background: The three factors within the Virchow triad play leading role in development of deep vein thrombosis (DVT) during pregnancy. (2) Methods: This research approaches various risk associated with DVT and its most representative complications, pulmonary thromboembolism cerebral venous thrombosis, pregnant postpartum women across a 15-year period (2007–2021). (3) Results: A total 201 out 287 patients had factors, while 86 did not present any. Out 47 developed thromboembolism, 12...
Endometriosis is a multifactorial disease that manifested by infertility and pelvic pain. The purpose of the study was to evaluate effect progesterone treatment on serum level osteopontin, multipotent cytokine, in patients with endometriosis. prospective we evaluated osteopontin levels were measured 40 endometriosis 12 healthy women using standardized Enzyme-Linked Immunosorbent Assay (ELISA) kit. Osteopontin seric lower increased after treatment. Because large dispersion data even control...
1) Background: The screening of preeclampsia (PE) and intrauterine growth restriction (IUGR) represents a constant challenge for obstetricians. aim this study was to determine compare the predictive performance 4 machine learning-based algorithms prediction PE, IUGR, their association in cohort singleton pregnancies; (2) Methods This prospective conducted at tertiary maternity hospital Romania, included 210 pregnancies that underwent first trimester screening. We clinical paraclinical data...
(1) Background: Neonatal early-onset sepsis (EOS) is associated with important mortality and morbidity. The aims of this study were to evaluate the association between serum biomarkers early onset neonatal in a cohort patients prolonged rupture membranes (PROM), calculate their diagnostic accuracy. (2) Methods: A retrospective was conducted on 1355 newborns PROM admitted January 2017 March 2020, who divided two groups: group A, ≥ 18 hours B, &lt; hours. Both groups further split into...
Along with the findings of recent years in medical imaging, a wide range contrast agents have been developed and used order to improve quality images acquired get diagnosis highest accuracy. Modern substances nuclear magnetic resonance imaging contain ions one or more free electrons, which fewer side effects are eliminated by kidney short time. This is MRI practice T1 section, where these reduce relaxation time increase signal strength. Our study included group 17 patients diagnosed cervical...
Preeclampsia is a rapidly progressive disorder characterized by high blood pressure and usually the presence of proteinuria. It occurs after 20 weeks gestation up to six postpartum. requires proper prenatal care which essential diagnose manage this disease. Our study show correlations between statistical data epidemiology issues, in order outline pregnancy profile with preeclampsia. We considered clinical biophysical markers preeclampsia 138 patient group. results encourage us deepen topic...
Human immunodeficiency virus (HIV) infection cannot be completely eliminated from the body because integrates its genetic code into that of host cell. The prevalence pregnancy in women with HIV has increased due to efficacy antiretroviral therapy (ART). Placental insufficiency is associated a reduction blood flow and circulatory redistribution, resulting fetal hypoxia nutrient deprivation as consequence an altered placental function, it can result lower birthweight. aim study was determine...