A5087192212- Pediatric Urology and Nephrology Studies
- Urinary Tract Infections Management
- Ureteral procedures and complications
- Kidney Stones and Urolithiasis Treatments
- Maternal and fetal healthcare
- Skin Protection and Aging
- Nonmelanoma Skin Cancer Studies
- Pelvic floor disorders treatments
- Bladder and Urothelial Cancer Treatments
- Urinary Bladder and Prostate Research
- Urological Disorders and Treatments
- Oral Health Pathology and Treatment
- Signaling Pathways in Disease
- Oral and Maxillofacial Pathology
- Protease and Inhibitor Mechanisms
- Peptidase Inhibition and Analysis
- Curcumin's Biomedical Applications
- Antimicrobial Peptides and Activities
- Nuclear Receptors and Signaling
- Oral and gingival health research
- Herpesvirus Infections and Treatments
- Renal and Vascular Pathologies
- Psoriasis: Treatment and Pathogenesis
- Colorectal Cancer Treatments and Studies
- Congenital heart defects research
Grigore T. Popa University of Medicine and Pharmacy
2018-2025
Morpho (United States)
2024
Salford Royal Hospital
2024
Spitalul Clinic Dr. C. I. Parhon
2022-2024
Hai phong University Of Medicine and Pharmacy
2019-2020
Background: Diabetes mellitus (DM) is a major risk factor for the development of periodontal disease and aggravates severity conditions. Matrix metalloproteinases (MMPs) are known to degrade ligament attachment bone matrix proteins. Increased expression CD147 associated with increased synthesis several MMPs, being modulator MMP expression, including that MMP-14. The purpose this study was quantify compare expressions MMP-14 in gingival tissues patients without type 2 diabetes mellitus....
Background and Objectives: Urosepsis is a significant cause of maternal fetal mortality. While certain risk factors for urinary tract infections (UTIs) in pregnant women are well established, those associated with an elevated urosepsis upper UTIs remain less defined. This study aims to identify linked increased examine urologic treatment outcomes such cases. Materials Methods: We conducted retrospective analysis on 66 diagnosed over nine-year period. A control group included 164 UTIs,...
Background and Objectives: Acute urologic complications, including bladder and/or ureteric injury, are rare but known events occurring at the time of caesarean section (CS). Delayed or inadequate management is associated with increased morbidity poor long-term outcomes. We conducted this study to identify risk factors for injuries CS in order inform obstetricians patients risks allow planning mitigate these risks. Materials Methods: reviewed all cases urological that occurred surgeries a...
Background and Objectives: Minimally invasive procedures, such as double-J ureteric stenting, could be a promising therapeutic alternative to conservative management of obstructive urinary tract pathology. We aimed evaluate the safety effectiveness stenting in pregnant women with ureterohydronephrosis or urolithiasis, along their infectious complications, assess pregnancy outcomes this cohort patients comparison control group. Materials Methods: This observational retrospective study...
The aim of the study was to compare profile COVID-19 (CoV)-infected patients with non-COVID-19 (non-CoV) who presented a multidrug-resistant urinary tract infection (MDR UTI) associated gut microbiota, as well analyze risk factors for their occurrence, types bacteria involved, and spectrum sensitivity.We conducted case-control on admitted urology clinic "Parhon" Teaching Hospital in Iasi, Romania, between March 2020 August 2022. group consisted 22 CoV MDR infections microbiota. For control...
(1) Background: Urinary tract infections (UTIs) are an important cause of perinatal and maternal morbidity mortality. The aim this study was to describe compare the main pregnancy outcomes among pregnant patients with complicated uncomplicated UTIs; (2) Methods: This retrospective included 183 who were evaluated for UTIs urosepsis in Urology Department ‘C.I. Parhon’ University Hospital, followed up at a tertiary maternity hospital- ‘Cuza-voda’ from Romania between January 2014 October 2023....
Background/Aim: Placenta percreta is a rare event, but it poses serious problems due to potential hemorrhagic events. We report particular case of placenta with massive hematuria maternal bladder invasion, and describe the surgical protocol performed that resulted in an excellent outcome. Case Report: A 33-year-old patient, at 27<sup>th</sup> weeks gestational age, presented emergency room Urology Department urinary blood clot acute retention, because from invasion. After extracting clots...
Background and Objectives: Urinary tract infections (UTIs) are an important cause of perinatal maternal morbidity mortality. The aim this study was to describe compare the main pregnancy outcomes among pregnant patients with complicated uncomplicated UTIs; Materials Methods: This retrospective included 183 who were evaluated for UTIs urosepsis in Urology Department ‘C.I. Parhon’ University Hospital, followed up at a tertiary maternity hospital—‘Cuza-voda’ from Romania between January 2014...
Vesicouterine fistula is a rare complication occurring mainly after cesarean sections. We present here particular case of vesicouterine (VUF) whose only symptom was urinary incontinence. describe the diagnostic methods used and surgical treatment to resolve case. A 30-year-old woman presented gynecology clinic with incontinence that occurred 5 days postoperatively section. The diagnosis made on basis computed tomography cystoscopy. Treatment consisted excision suturing bladder uterine wall,...
: Multidrug-resistant urinary tract infections (MDR UTIs) constitute an important public health problem, especially in pregnant patients. The aim of this retrospective study was to characterize the bacterial spectrum and profile microbial resistance cases UTIs occurring women, as well their impact on obstetrical neonatal outcomes.
Double-J ureteral catheters in patients with lithiasis undergoing extracorporeal shockwave lithotripsy (ESWL) procedures reduce the efficacy of procedure or have no effect on stone-free rate. However, double-J whom they were inserted for infected hydronephrosis is not known. The aim our study was to evaluate and safety ESWL previously hydronephrosis.
Diabetes mellitus is one of the most common endocrinopathies, estimated to affect about 5.4% world&#039;s population around 2025. It thought that nearly a third diabetic patients have some type skin condition. Frequently, cutaneous effects this heterogeneous syndrome are ac-curately detected late in progressive form disease. The main objective present study was identify cellular characteristics microenvironment exper- imentally induced diabetes mellitus. Skin fragments were harvested...
Background: The aim of our study was to analyze the factors associated with increased risk urinary tract infection (UTI) carbapenem-resistant (CR) Klebsiella pneumoniae (Kpn) and antibiotic resistance spectrum strains in patients. As secondary objectives, we elaborated profile these patients incidence different types carbapenemases. Methods: We conducted a retrospective case-control which compared group 62 infections CR Kpn control consisting 136 multidrug-resistant (MDR), but...
The aim of this study was to analyze the characteristics pyelonephritis with multidrug-resistant (MDR) bacteria in pregnant women comparison multidrug-sensitive particular patient group.
Background: Diabetes mellitus is one of the most common endocrinopathies, estimated to affect about 5.4% world&#039;s population around 2025. It thought that nearly a third diabetic patients have some type skin condition. Frequently, cutaneous effects this heterogeneous syndrome are accurately detected late in progressive form disease. Methods: Skin fragments were harvested from adult white Wistar rats both sexes, with weight 200 g, 12 weeks after streptozotocin diabetes was induced. In...
The results of the recent years researches support need for personalized therapeutic cancer by completing clinical, imagistic and histopathological diagnosis with molecular studies to identify new useful biomarkers diagnosis, prognosis tumor progression. Maspin is a non-inhibitory serine protease having proapoptotic activity, suppressor invasion, metastasis angiogenesis. Ezrin member Ezrin/Radixin/Moesin (ERM) family, involved in cellular adhesion mechanisms, motility invasiveness cells. In...
Abstract α, β, θ defensins represent a family of small antimicrobial peptides expressed predominantly by series cells, including neutrophils, monocytes-macrophages and epithelial cells that are involved in defense mechanisms against viral infections. β-defensins the most widespread this being encountered oral, digestive, urogenital mucosa cutaneous lesions. directly inactivate certain viruses, human papillomavirus(HPV) suppressing replication altering target cells. Considering these aspects,...
Over the years, keratoacanthomas have been described as some of most common skin lesions with potential for malignant transformation, thus constituting an important risk factor development squamous cell carcinoma. The quantification transformation is conditioned by clinical–morphological and etiopathogenic variability these lesions, a negative impact on diagnostic therapeutic management. In this sense, main objective research to characterize from ultrastructural perspective specific tumour...