A5009707385- Endometriosis Research and Treatment
- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Uterine Myomas and Treatments
- Gynecological conditions and treatments
- Maternal and fetal healthcare
- Pregnancy and preeclampsia studies
- COVID-19 Impact on Reproduction
- Cervical Cancer and HPV Research
- Parvovirus B19 Infection Studies
- Inflammatory Biomarkers in Disease Prognosis
- Gestational Diabetes Research and Management
- Reproductive System and Pregnancy
- COVID-19 Clinical Research Studies
- Multiple Sclerosis Research Studies
- Blood Coagulation and Thrombosis Mechanisms
- Ovarian function and disorders
- Galectins and Cancer Biology
- Pregnancy and Medication Impact
- Prenatal Screening and Diagnostics
- Birth, Development, and Health
- Cardiovascular Issues in Pregnancy
- Ectopic Pregnancy Diagnosis and Management
- Erythropoietin and Anemia Treatment
- Venous Thromboembolism Diagnosis and Management
Grigore T. Popa University of Medicine and Pharmacy
2016-2025
Clinical Emergency Hospital Bucharest
2022-2024
Yahoo (United Kingdom)
2018
Institutul Regional de Oncologie
2017
The study introduces the 2LIO test as a novel diagnostic tool for assessing carpal tunnel syndrome (CTS) severity by combining distal motor latency (DML) differences and amplitude ratio (AR) of interosseous lumbrical muscles. This retrospective cohort included 264 patients grouped CTS severity, highlighting demographic clinical features each group. mean age varied slightly across groups, with notable female predominance. demonstrated high accuracy, sensitivity specificity 93.3% 97.7%,...
The high energy of α emitters, and the strong linear transfer that goes along with it, lead to very efficient cell killing through DNA damage. Moreover, degree oxygenation cycle state have no impact on these effects. Therefore, radioisotopes can offer a treatment choice individuals who are not responding β- or gamma-radiation therapy chemotherapy drugs. Only few α-particle emitters suitable for targeted alpha (TAT) clinical applications. majority available research involves 225Ac its...
The use of nuchal translucency (NT) in 1992 by Nicolaides et al was a major breakthrough screening for chromosomal aneuploidies at the end first trimester. However, pathological conditions other than are also associated with increased NT, which can be detected normal fetuses. This study sought to evaluate causes this ultrasound sign group patients from Iasi, Romania. During decade-long period, there were 71 certified cases involving NT; these underwent diagnostic amniocentesis and...
During viral outbreaks, pregnancy poses an increased risk of infection for women.In a prospective study, all patients admitted delivery at term to Elena Doamna Obstetrics and Gynecology University Hospital in Iasi, Romania, between 1 April 2020 31 December were included. There 457 patients, divided into two groups: group 1, SARS-CoV-2-positive (n = 46) 2, SARS-CoV-2-negative 411). Among other tests, complete blood count was determined upon admittance, the following values studied: white cell...
Ovarian cancer (OC) still registers a high prevalence in female gynecological pathology. Given the aggressiveness of tumor and lack response to conventional therapies, current research interest is identification new prognostic markers. Gal-8, member galectin family molecules, involved tumorigenesis, disease progression, metastasis, has been assigned as valuable factor, its inhibition may open perspectives therapeutic management. Few studies have carried out so far evaluate OCs’ profiles. Our...
(1) Background: The prediction of cervical lesions evolution is a challenge for clinicians. prospective study aimed to determine and compare the predictive accuracy cytology, HPV genotyping, p16/Ki67 dual staining alone or in combination with personal risk factors progression, regression persistence human papillomavirus (HPV)-infected patients; (2) Methods: This included HPV-positive patients without that underwent follow-up. Descriptive statistics sensitivity analysis individual combined...
(1) Background: The prediction of cervical lesion evolution is a challenge for clinicians. This prospective study aimed to determine and compare the predictive accuracy cytology, HPV genotyping, p16/Ki67 dual staining alone or in combination with personal risk factors progression, regression, persistence lesions human papillomavirus (HPV)-infected patients; (2) Methods: included HPV-positive patients without who underwent follow-up private clinic. We calculated performance individual tests...
Background and objectives: Kisspeptin, also named metastin, showed important roles in initiating the secretion of gonadotropin-releasing hormone (GnRH) is an essential factor development polycystic ovaries syndrome (PCOS). Several research studies noticed associations between kisspeptin levels patients with anovulatory cycles due to PCOS increased LH/FSH ratio. The aim our study was bring scientific evidence regarding correlation high luteinizing values subfertile women PCOS. Materials...
: The susceptibility of pregnant patients at term to SARS-CoV-2 infection regarding the ABO and Rh blood group polymorphism was analyzed in this study.
: (1) Background: Seasonality is an important environmental factor that influences immune responses (2) Methods: In a retrospective study, we included all pregnant patients admitted to the Elena Doamna Obstetrics and Gynecology Hospital with critical form of COVID-19 infection between 1 January December 2021. The blood counts collected on specific A, H E Brixia score- collection days, or ones closest those were considered in our study. We also studied differences two groups regarding...
The early diagnosis of dental caries has an important role in pregnancy, as it allows establishing preventive measures. Besides the clinical examination, there are modern preclinical ways detecting odontal lesions such electrical conductivity (EC) and quantitative Light-Induced Fluorescence (QLF). Dental radiography three-dimensional (3D) orthopantomography, although useful, forbidden during pregnancy (6). Bacteriological evaluation detection demineralized areas allow measures aimed at...
Background: Uterine involution assessments are critical for the prevention of postpartum hemorrhage. Various methods have been used worldwide. Methods: The PUUS (Postpartum Ultrasonographic Scale) method evaluates, by transabdominal ultrasonography, length endometrium uterine cavity occupied blood or debris, from grade 0 (no blood) to 4 (over three-quarters endometrial blood/debris). A total 131 consecutive patients admitted delivery in Elena Doamna Obstetrics and Gynecology University...
Endometriosis represents an estrogen-dependent disease of the female reproductive system and intra- extraperitoneal regions, with chronic feature. Currently, immune cells, such as macrophages lymphocytes, are considered to play a pivotal role in angiogenesis invasion endometriotic cells through matrix remodeling. Additionally, various studies have revealed E-cadherin, β-catenin, along steroid hormone receptors endometriosis development. In this context, our study aimed analyze relationship...
Atypical polypoid adenomyoma (APAM) is a rare benign tumor of the uterus that causes irregular vaginal bleeding in women reproductive age. It has potential for malignant transformation, but it does not metastasize. APAM may coexist with endometrial hyperplasia and adenocarcinoma, usually leading to misdiagnosis. Histopathologically, biphasic tumor, represented by endometrioid glands complex histoarchitecture, sometimes squamous morular metaplasia or cytologic atypia, interspersed...
Cervical cancer represents a major health problem in Romania. A national population-based cervical screening programme was launched 2012. The aims of the study were to assess participation rate and estimate prevalence epithelial cell abnormalities first four years North Eastern Romania.The rate, representing proportion eligible women screened programme, evaluated for 2012-2016. cytological estimated by age group calendar year.Of 107,968 Pap smears taken, 312 unsatisfactory (0.3%). number...