- Prenatal Screening and Diagnostics
- Parvovirus B19 Infection Studies
- Congenital Anomalies and Fetal Surgery
- Pregnancy and preeclampsia studies
- Cardiovascular Issues in Pregnancy
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Tracheal and airway disorders
- Congenital Heart Disease Studies
- Ovarian function and disorders
- Urological Disorders and Treatments
- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Dermatology and Skin Diseases
- Fetal and Pediatric Neurological Disorders
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Birth, Development, and Health
- Renal function and acid-base balance
- Congenital gastrointestinal and neural anomalies
Grigore T. Popa University of Medicine and Pharmacy
2013-2020
Clinical Emergency Hospital Bucharest
2011-2012
The use of nuchal translucency (NT) in 1992 by Nicolaides et al was a major breakthrough screening for chromosomal aneuploidies at the end first trimester. However, pathological conditions other than are also associated with increased NT, which can be detected normal fetuses. This study sought to evaluate causes this ultrasound sign group patients from Iasi, Romania. During decade-long period, there were 71 certified cases involving NT; these underwent diagnostic amniocentesis and...
Abstract Background Fetal nucleated red blood cells (NRBC) from maternal circulation are rare events but can be enriched and used to evaluate the genetics of fetus. We compared two simplified selection methods fetal blood. Methods isolated through double‐density gradient centrifugation followed either by magnetic cell selection, based on paramagnetic proprieties NRBC hemoglobin, converted methemoglobin, or a positive magnetic‐activated sorting (MACS) enrichment, using anti‐CD71 monoclonal...
A rare cause of infertility is the lack fertilisation with spontaneous activation oocytes, leading to parthenogenesis. We present such a case. The patient was G1P0 38-year-old woman African ethnicity, who requested an in vitro (IVF) donor sperm. She received stimulation protocol 75 IU FSH/LH from day 3 cycle, which she interrupted after 2 d, and restarted same dosage for another d 7, plus one administration GnRH antagonist 10 cycle. With follicle reaching 19 mm on 11, estradiol 325 ng/ml,...
Limb Body Wall Complex (LBWC) is a combination of development abnormalities involving the neural tube, body wall and limbs. There are few cases in literature, our case only 2nd presented from Romania. The patient was 31 year-old women G1P0A0 with 33 week pregnancy which had no prenatal care. ultrasound scan described several abnormalities, including: large abdominal defect, difficult to identify pelvic organs ambiguous genitalia; enlarged stomach suspicion intestinal atresia; scoliosis spida...
The purpose of this work is to underline the possibilities prenatal diagnostic aberrant right subclavian artery (ARSA) in routine second trimester pregnancy, by using colour Doppler three vessels + trachea view. Extended fetal echocardiography was performed. For identification ARSA used systematically differential diagnosis between and hemiazygos vein performed pulsating Doppler. In all cases with amniocentesis FISH test were recommended. associated aneuploidies or heart disease therapeutic...
To determine the presence of a single umbilical artery and its association with malformations abnormal karyotypes. We prospectively studied 115 singleton pregnancies prenatally identified artery. reviewed pregnancy data, absent side, Doppler findings perinatal outcome. All fetuses were confirmed to have after delivery. Gestational age at time diagnosis ranged from 15 24 weeks. Among cases postnatal information, 32 (27.8%) had structural abnormalities, often involving multiple organs. The...
To present the importance of fetal echocardiography (Doppler eFlow mode) from screening performed in first trimester pregnancy (protocol Fetal Medicine Foundation) identification aberrant right subclavian artery (ARSA) I endovaginal at 12–13 + 6 wk. For arteries it was used Doppler and pulse for differentiates ARSA azygos vein. In cases with high risk chromosomal pathology recommended vilosity punction or amniocentesis. confirmed pathology, therapeutic abortion. All alive newborns were...