We compared high-resolution computed tomography (HRCT) with chest radiography (CR) to determine if there is any advantage using HRCT in the diagnosis of community-acquired pneumonia (CAP). Simultaneously obtained radiographs were scans for 47 patients clinical symptoms and signs suspicious CAP. identified all 18 CAP cases (38.3%) apparent on as well eight additional (i.e., 55.3%); P = .004. The corresponding figures bilateral involvement six by CR (33.3%) 16 (61.5%), .001. did not show...

Abstract The basic feature in the pathogenesis of abdominal aortic aneurysm (AAA) is degradation extracellular matrix components. This process induced partly by cytokines secreted from inflammatory and mesenchymal cells. Circulating levels were studied AAA patients compared with subjects suffering atherosclerotic disease only. Furthermore, predictive value cytokine concentrations was evaluated for expansion rate. interleukin 1β (IL-1β), 6 (IL-6), tumor necrosis factor-α (TNF-α), interferon-γ...

Background. The role of viral infections in the etiology severe community-acquired pneumonia (SCAP) was prospectively evaluated from 2008 to 2012 at a university-level intensive care unit.

BACKGROUND: The importance of Chlamydia pneumoniae as a cause pneumonia has remained controversial. clinical picture C and Streptococcus in patients admitted to hospital with community-acquired was compared during epidemic Finland. METHODS: Group I consisted 24 whom serological testing bacterial culture indicated an association only, group II comprised nine both S pneumoniae, III 13 only. RESULTS: suffered from headache more frequently than the other (group I, 46%; II, 11%; III, 15%) had...

Journal Article The Etiology of Community-Acquired Pneumonia among Hospitalized Patients during a Chlamydia pneumoniae Epidemic in Finland Get access Maritta T. Kauppinen, Kauppinen Reprints or correspondence: Dr. M. Oulu University Hospital, Clinical Microbiology Laboratory, Kajaanintie 50 A, FIN-90220 Oulu, Finland. Search for other works by this author on: Oxford Academic PubMed Google Scholar Elja Herva, Herva Pekka Kujala, Kujala Maija Leinonen, Leinonen Saikku, Saikku Hannu Syrjälä...

In a previous study we observed an increasing trend in candidemia Finland the 1990s. Our aim was now to investigate further population-based secular trends, as well outcome, and evaluate association of fluconazole consumption prophylaxis policy with findings. We analyzed laboratory-based surveillance data on from National Infectious Diseases Register during 2004-2007 Finland. Data consumption, expressed defined daily doses, DDDs, obtained Agency for Medicines, regional policies were assessed...

Abstract Background Neuroinflammation often develops in sepsis along with increasing permeability of the blood-brain barrier (BBB), which leads to septic encephalopathy. The is formed by tight junction structures between cerebral endothelial cells. We investigated expression proteins related brain autopsy specimens critically ill patients deceased and analyzed relationship BBB damage measures systemic inflammation organ dysfunction. Methods case series included all (385) adult due years...

Objective To determine changes in hand-hygiene compliance after the introduction of direct observation practice for doctors and nurses, evaluate relationship between incidence health-care-associated infections.Methods We conducted an internal audit survey a tertiary-care hospital Finland from 2013 to 2018.Infection-control link nurses observed practices based on World Health Organization's strategy hand hygiene.We calculated as number observations where necessary was practised divided by...

The aim of this study was to elucidate the impact intensive care unit (ICU)-acquired infection on hospital mortality.Patients with a longer than 48 hour stay in mixed 10 bed ICU tertiary-level teaching were prospectively enrolled between May 2002 and June 2003. Risk factors for mortality analyzed logistic regression model.Of 335 patients, 80 developed ICU-acquired infection. Among patients infections, always higher, regardless whether or not had admission (infection group (IAG), 35.6% versus...

Background: Acute acalculous cholecystitis (AAC) is a serious complication of critical illness. We evaluated the underlying diseases, clinical and diagnostic features, severity associated organ failures, outcome operatively treated AAC in mixed ICU patient population. Methods: The data all patients who had confirmed during their stay between 1 January 2000 31 December 2001 were collected from hospital records intensive care unit's management system for predetermined variables. Results:...

In a tularemia epidemic during 1982 in northern Finland, 53 patients showed no peripheral portal of entry for infection or associated lymphadenopathy. Respiratory symptoms were observed 72% the patients. 26/38 cases had abnormal chest films. Hilar adenopathy was most common finding (36%). Four did not receive antibiotics; 43 received tetracyclines, 5 streptomycin and 1 cefuroxime amoxycillin. All recovered. 50 acquired farming activities, such as making fresh hay with hay-cutter, handling...

In Europe few studies have analyzed the costs of treating aseptic revisions and prosthetic joint infections with either debridement, antibiotics implant retention or two-stage revision, as compared to cost a primary total arthroplasty.The purpose was analyze arthroplasties, treated revision. We conducted retrospective cohort study patients who had arthroplasty in Oulu University Hospital during three-year period from 2013 2015. The were divided specific services (e.g. procedure costs, ward...

Aims: To illustrate the histopathological features of acute acalculous cholecystitis (AAC) critically ill patients and to compare them with those calculous (ACC) normal gallbladders. Methods results: We studied 34 gallbladders AAC compared 28 cases ACC 14 Histological were systematically evaluated. Typical in bile infiltration, leucocyte margination blood vessels lymphatic dilation. Bile infiltration gallbladder wall was more common extended wider deeper into muscle layer ACC. Epithelial...

88 tularemia patients with secondary skin manifestations seen in northern Finland during 1967-1983 are described this paper. Tularemia was ulceroglandular 57% and pulmonary 27% of the patients. 68% were women. The most common manifestation papular or vesicopapular eruption which 42% Erythema nodosum either alone combination some other encountered 28% erythema multiforme 9% more often than types disease (p less 0.01). clinical pictures caused by greatly resembled those Yersinia. should be...

We assessed whether magnetic resonance imaging (MRI) is applicable for diagnosing pneumonia among adult outpatients with lower respiratory tract infection. Patients were recruited prospectively when they had symptoms ≤7 days and fever ≥37.8 °C. The patients underwent high-resolution computed tomography (HRCT), MRI chest radiography, which repeated 1 month later if necessary, to verify pneumonia. duration of examination was 3–4 min. Among 77 patients, HRCT, radiography identified 32 (41.6%),...

To identify preoperative and perioperative features that may lead to a risk of surgical-site infection (SSI) after coronary artery bypass surgery.884 patients who underwent grafting in 1992 1993 were studied. The associations between 23 the presence SSI at donor site or chest area evaluated by univariate analysis followed multivariate logistic regression analysis.A university hospital.172 (19.5%) either had an recorded before discharge received antibiotics prescribed for suspected during...

Serum concentrations of myoglobin (S-Myo) and carbonic anhydrase III (S-CA III; EC 4.2.1.1), a skeletal muscle-specific protein, were measured by RIA in 26 patients with acute myocardial infarction, 14 neuromuscular diseases, six healthy subjects before after physical exercise. S-Myo was increased infarct patients, whereas S-CA not altered. In diseases exercise, both significantly increased. also showed identical peak times, 2 h postexercise. The S-Myo/S-CA ratio always higher than the other...