A5080220425- Flavonoids in Medical Research
- melanin and skin pigmentation
- Lung Cancer Treatments and Mutations
- Food Quality and Safety Studies
- MicroRNA in disease regulation
- Natural product bioactivities and synthesis
- Phytochemicals and Antioxidant Activities
- Calpain Protease Function and Regulation
- PI3K/AKT/mTOR signaling in cancer
- Tea Polyphenols and Effects
- Saffron Plant Research Studies
- Fungal Biology and Applications
- Antioxidant Activity and Oxidative Stress
- Retinoids in leukemia and cellular processes
- Curcumin's Biomedical Applications
- Skin Protection and Aging
- Tannin, Tannase and Anticancer Activities
- Essential Oils and Antimicrobial Activity
- Epigenetics and DNA Methylation
- TGF-β signaling in diseases
- Glioma Diagnosis and Treatment
- Mathematical Biology Tumor Growth
- Cancer Cells and Metastasis
- Pancreatic function and diabetes
Seoul National University
2024
Kyung Hee University
2018-2020
Konkuk University
2016-2017
Hydroxytyrosol is discovered in a form of elenolic acid ester oleuropein olive leaf and oil. The anti-carcinogenic, antioxidant, anti-inflammatory effects hydroxytyrosol have been reported the food, medical, pharmaceutical, life science fields. But it has not studied on skin biology field. This study demonstrated using UVA-induced cellular aging model human dermal fibroblast. cell survival rate was measured principle water-soluble tetrazolium salt-1 assay, which measurement method for rate....
Objective: Inflammation is crucial to limiting vascular disease.Previously we reported that acrolein, a known toxin in tobacco smoke, might play an important role the progression of atherosclerosis via inflammatory response involving cyclooxygenase-2 (COX-2) and prostaglandin production human umbilical vein endothelial cells (HUVECs).Curcumin has been improve function have anti-inflammatory properties.In this study, investigated whether curcumin prevents induction caused by acrolein.Methods:...
This study examines the cellular protective effects of scutellarin on HaCaT cells in which oxidative stress was induced by ultraviolet A (UVA). Cell viability and lipid peroxidation were measured using WST-1 MDA assays, respectively. The changes cell number sub-G1 phase assessed cycle analysis, tailed DNA levels comet assay to examine degree damage. difference mitochondrial membrane potential examined JC-1 staining, regulation BAX mRNA expression quantitative real-time polymerase chain...
Glioblastoma (GBM) has a fatal prognosis because of its aggressive and invasive characteristics. Understanding the mechanism invasion necessitates an elucidation relationship between tumor cells microenvironment. However, there been scarcity suitable models to investigate this. In this study, we established glioblastoma‐cerebral organoid assembloid (GCOA) model by co‐culturing patient‐derived GBM tumoroids human cerebral organoids. Tumor from infiltrated organoids, mimicking nature parental...
목ì 본 ì°êµ¬ë ë ¸ë£¨ê¶ë ì´ ë²ì¯ ì¶ì¶ë¬¼ì ë©ë¼ë í©ì± ë° ì°í ì¤í¸ë ì¤ ì¡°ì ì 미ì¹ë ìí¥ì ì¡°ì¬íëë° ê·¸ ì´ ìë¤. ë°©ë² ë²ì¯ì ê°ê° 95% ìíì¬ê³¼ ì¦ë¥ìë¡ ì¶ì¶íìê³ , ìíì¬ ì¶ì¶ë¬¼ì ë¤ì ì¦ë¥ìì í´ë¡ë¡í¬ë¦ì¼ë¡ ë¶ííìë¤. í©ì±ëì B16F1 ì¸í¬ë¥¼ íµí´ íì¸íìê³ ì¸í¬ ë ì±ì ì¸í¬ì HaCaT MTT assay ë°©ë²ì¼ë¡ íì¸íìë¤. ëí, β-catenin/Tcf íì±ì luciferase assay를 측ì...
목ì 본 ì°êµ¬ì ì ultraviolet A (UVA)ë¡ë¶í° ì°íì ì¤í¸ë ì¤ê° ì ëë ì¸ê°ê°ì§íì±ì¸í¬ìì scutellarinì ì°íìµì í¨ë¥ì íì¸íëë° ìë¤. ë°©ë² Scutellarinì íì°í íì¸í기 ìíì¬ water-soluble tetrazolium salt (WST-1) assay를 ì´ì©í ì¸í¬ë ì± ì¸¡ì , 2â²,7â²-dichlorofluorescin diacetate (DCFDA) íµí ì¸í¬ ë´ íì±ì°ìì¢ ì ëë¶ì ê·¸ë¦¬ê³ quantitative realtime polymerase chain reaction (qRT-PCR)ì íµí´ superoxide...