- Peripheral Artery Disease Management
- Cerebrovascular and Carotid Artery Diseases
- Vascular Procedures and Complications
- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Cardiac Arrhythmias and Treatments
- Aortic aneurysm repair treatments
- Coronary Interventions and Diagnostics
- Cardiovascular Effects of Exercise
- Cardiac Imaging and Diagnostics
- Renal and Vascular Pathologies
- Blood Coagulation and Thrombosis Mechanisms
- Vascular anomalies and interventions
- Central Venous Catheters and Hemodialysis
- Advanced MRI Techniques and Applications
- Coronary Artery Anomalies
- Folate and B Vitamins Research
- Atherosclerosis and Cardiovascular Diseases
- Vasculitis and related conditions
- Hormonal Regulation and Hypertension
- Cardiovascular Disease and Adiposity
- Blood properties and coagulation
- Economic and Fiscal Studies
Jagiellonian University
2001-2019
Krakow Cardiovascular Research Institute
2010-2018
SRH Klinikum Karlsbad-Langensteinbach
2017
St. John's Hospital
2017
NZOZ Centrum Alergologii
2008-2010
European School of Law and Administration
1999
Collegium Medicum in Bydgoszcz
1994-1997
New York Academy of Medicine
1992
Background— Studies assessing drug-coated balloons (DCB) for the treatment of femoropopliteal artery disease are encouraging. However, challenging lesions, such as severely calcified, remain difficult to treat with DCB alone. Vessel preparation directional atherectomy (DA) potentially improves outcomes DCB. Methods and Results— DEFINITIVE AR study (Directional Atherectomy Followed by a Paclitaxel-Coated Balloon Inhibit Restenosis Maintain Patency—A Pilot Study Anti-Restenosis Treatment) was...
Frequently an inherited predisposition to thrombosis remains clinically silent until additional environmental factor intervenes. The present study aimed assess distribution of risk factors venous in patients with thromboembolism (VTE). prevalences V Leiden (FV Leiden), prothrombin II G20210A (FII G20210A), C677T and A1298C methylenetetrahydrofolate reductase (MTHFR) mutations were studied 149 VTE 100 controls. following key risks established: previous deep or pulmonary embolism (23.5%), bed...
Purpose:To report the 2-year results of MELODIE trial, which evaluated safety and effectiveness balloon-expandable Express LD Vascular stent for treatment atherosclerotic iliac artery disease. Methods:This prospective, multicenter, single-arm trial enrolled 151 patients (113 men; mean age 60.1±8.4 years) with 163 de novo or restenotic lesions. The primary endpoint, 6-month angiographic percent loss luminal diameter, was compared to an objective performance criterion (OPC) based on published...
To evaluate the safety and efficacy of Serranator Alto PTA Serration Balloon Catheter in subjects with peripheral artery disease superficial femoral popliteal arteries.A prospective, multicenter, single-arm feasibility study enrolled 25 patients (mean age 66 years; 18 men) to inflation postinflation effects under monitoring by independent core laboratories. Inclusion criteria were claudication or ischemic rest pain, de novo lesions native restenosis, >70% stenosis, lesion length <10 cm, a...
Patients with critical limb ischemia (CLI) are at increased risk of cardiovascular complications and mortality. To determine (1) incidence myocardial injury following endovascular revascularization, (2) relationship between 1-year mortality major adverse events (MACE; i.e., composite infarction, stroke, death). Single-center, prospective cohort study CLI patients ≥ 45 years age, who underwent revascularization overnight hospitalization. High-sensitive troponins T (hsTnTs) were measured on...
Coronary flow reserve was assessed in a patient with Anderson-Fabry disease complicated by symmetric left ventricular hypertrophy. measurable all three major coronary arteries providing an opportunity to compare regional from different vascular beds. In this the beds supplied diffusely hypertrophied myocardium. disturbances small intramyocardial perforating were visible. The reduced similar level (around 2.0) arteries. our disease, vasodilatation blunted diffuse pattern corresponding...
Summary There have been several reports on alterations of platelet function and raised plasma heparin levels in symptom‐free atopic subjects. Either these can affect formation thrombin vivo . In 25 patients 32 healthy volunteers we studied the generation blood emerging from a standardized skin microvasculature injury, which also served to determine bleeding time. Generation was delayed atopies. They produced significantly less (P<0.01) during early central phase haemostasis. The amount...
Monocytes are mononuclear cells characterized by distinct morphology and expression of CD14 CD16 surface receptors. Classical, quiescent monocytes positive for (lipopolysaccharide receptor) but do not express Fc gamma receptor III (CD16). Intermediate coexpress CD14. Nonclassical with low represent mature macrophage-like monocytes. Monocyte behavior in peripheral arterial disease (PAD) during vessel wall directed treatment is well defined. This observation study aimed at monitoring acute...
To test the feasibility and accuracy of transthoracic, harmonic mode, contrast enhanced Doppler echocardiographic assessment lesion severity after PCI treatment in native coronary arteries--the LAD, Cx RCA.Prospective evaluation 59 patients (66 arteries). Restenosis was diagnosed whenever maximal flow velocity at least doubled comparison to segment immediately proximal site or when local 2 m/s. At 9 months follow-up final echocardiography angiography performed with regard 44 arteries 40...
Validation of Polish VascuQol 167 as well daily functional status associated with PAD and treatment process. 2 For this reason, objective clinical assessments were extended by patient -reported outcome measures.The most common generic questionnaires, the Medical Outcome Study Short Form -36 (SF -36) 3 INTRODUCTION Chronic limb ischemia has an adverse effect on quality life. 1 Evaluation outcomes peripheral arterial disease (PAD) based parameters does not allow for a reliable assessment pain...
In a double-blind cross-over study 20 mg of aspirin or placebo were administered to 18 patients with respiratory atopy without eczema and 12 healthy controls. Mean bleeding time before administration either was on average about 1 min. longer in atopics than the controls, this difference significant (p 0.05). Atopics' platelets also aggregated less well response arachidonic acid comparison On contrary, no platelet aggregability detected PAF-acether alone combination subthreshold, synergistic...