Marek Krzanowski

ORCID: 0000-0002-2896-4587
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About
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Research Areas
  • Peripheral Artery Disease Management
  • Cerebrovascular and Carotid Artery Diseases
  • Vascular Procedures and Complications
  • Cardiomyopathy and Myosin Studies
  • Cardiovascular Function and Risk Factors
  • Venous Thromboembolism Diagnosis and Management
  • Diagnosis and Treatment of Venous Diseases
  • Cardiac Arrhythmias and Treatments
  • Aortic aneurysm repair treatments
  • Coronary Interventions and Diagnostics
  • Cardiovascular Effects of Exercise
  • Cardiac Imaging and Diagnostics
  • Renal and Vascular Pathologies
  • Blood Coagulation and Thrombosis Mechanisms
  • Vascular anomalies and interventions
  • Central Venous Catheters and Hemodialysis
  • Advanced MRI Techniques and Applications
  • Coronary Artery Anomalies
  • Folate and B Vitamins Research
  • Atherosclerosis and Cardiovascular Diseases
  • Vasculitis and related conditions
  • Hormonal Regulation and Hypertension
  • Cardiovascular Disease and Adiposity
  • Blood properties and coagulation
  • Economic and Fiscal Studies

Jagiellonian University
2001-2019

Krakow Cardiovascular Research Institute
2010-2018

SRH Klinikum Karlsbad-Langensteinbach
2017

St. John's Hospital
2017

NZOZ Centrum Alergologii
2008-2010

European School of Law and Administration
1999

Collegium Medicum in Bydgoszcz
1994-1997

New York Academy of Medicine
1992

Background— Studies assessing drug-coated balloons (DCB) for the treatment of femoropopliteal artery disease are encouraging. However, challenging lesions, such as severely calcified, remain difficult to treat with DCB alone. Vessel preparation directional atherectomy (DA) potentially improves outcomes DCB. Methods and Results— DEFINITIVE AR study (Directional Atherectomy Followed by a Paclitaxel-Coated Balloon Inhibit Restenosis Maintain Patency—A Pilot Study Anti-Restenosis Treatment) was...

10.1161/circinterventions.116.004848 article EN cc-by Circulation Cardiovascular Interventions 2017-09-01

Frequently an inherited predisposition to thrombosis remains clinically silent until additional environmental factor intervenes. The present study aimed assess distribution of risk factors venous in patients with thromboembolism (VTE). prevalences V Leiden (FV Leiden), prothrombin II G20210A (FII G20210A), C677T and A1298C methylenetetrahydrofolate reductase (MTHFR) mutations were studied 149 VTE 100 controls. following key risks established: previous deep or pulmonary embolism (23.5%), bed...

10.1183/09031936.03.00034302 article EN European Respiratory Journal 2003-01-01

Purpose:To report the 2-year results of MELODIE trial, which evaluated safety and effectiveness balloon-expandable Express LD Vascular stent for treatment atherosclerotic iliac artery disease. Methods:This prospective, multicenter, single-arm trial enrolled 151 patients (113 men; mean age 60.1±8.4 years) with 163 de novo or restenotic lesions. The primary endpoint, 6-month angiographic percent loss luminal diameter, was compared to an objective performance criterion (OPC) based on published...

10.1583/09-2917mr.1 article EN Journal of Endovascular Therapy 2010-10-01

To evaluate the safety and efficacy of Serranator Alto PTA Serration Balloon Catheter in subjects with peripheral artery disease superficial femoral popliteal arteries.A prospective, multicenter, single-arm feasibility study enrolled 25 patients (mean age 66 years; 18 men) to inflation postinflation effects under monitoring by independent core laboratories. Inclusion criteria were claudication or ischemic rest pain, de novo lesions native restenosis, >70% stenosis, lesion length <10 cm, a...

10.1177/1526602818820787 article EN Journal of Endovascular Therapy 2018-12-24

Patients with critical limb ischemia (CLI) are at increased risk of cardiovascular complications and mortality. To determine (1) incidence myocardial injury following endovascular revascularization, (2) relationship between 1-year mortality major adverse events (MACE; i.e., composite infarction, stroke, death). Single-center, prospective cohort study CLI patients ≥ 45 years age, who underwent revascularization overnight hospitalization. High-sensitive troponins T (hsTnTs) were measured on...

10.1007/s00392-017-1185-z article EN cc-by Clinical Research in Cardiology 2017-11-24

Coronary flow reserve was assessed in a patient with Anderson-Fabry disease complicated by symmetric left ventricular hypertrophy. measurable all three major coronary arteries providing an opportunity to compare regional from different vascular beds. In this the beds supplied diffusely hypertrophied myocardium. disturbances small intramyocardial perforating were visible. The reduced similar level (around 2.0) arteries. our disease, vasodilatation blunted diffuse pattern corresponding...

10.1186/1476-7120-3-11 article EN cc-by Cardiovascular Ultrasound 2005-04-27

Summary There have been several reports on alterations of platelet function and raised plasma heparin levels in symptom‐free atopic subjects. Either these can affect formation thrombin vivo . In 25 patients 32 healthy volunteers we studied the generation blood emerging from a standardized skin microvasculature injury, which also served to determine bleeding time. Generation was delayed atopies. They produced significantly less (P&lt;0.01) during early central phase haemostasis. The amount...

10.1111/j.1365-2222.1991.tb01680.x article EN Clinical & Experimental Allergy 1991-07-01

Monocytes are mononuclear cells characterized by distinct morphology and expression of CD14 CD16 surface receptors. Classical, quiescent monocytes positive for (lipopolysaccharide receptor) but do not express Fc gamma receptor III (CD16). Intermediate coexpress CD14. Nonclassical with low represent mature macrophage-like monocytes. Monocyte behavior in peripheral arterial disease (PAD) during vessel wall directed treatment is well defined. This observation study aimed at monitoring acute...

10.1155/2016/2708957 article EN cc-by BioMed Research International 2016-01-01

To test the feasibility and accuracy of transthoracic, harmonic mode, contrast enhanced Doppler echocardiographic assessment lesion severity after PCI treatment in native coronary arteries--the LAD, Cx RCA.Prospective evaluation 59 patients (66 arteries). Restenosis was diagnosed whenever maximal flow velocity at least doubled comparison to segment immediately proximal site or when local 2 m/s. At 9 months follow-up final echocardiography angiography performed with regard 44 arteries 40...

10.1016/j.euje.2003.10.004 article EN European Journal of Echocardiography 2003-12-04

Validation of Polish VascuQol 167 as well daily functional status associated with PAD and treatment process. 2 For this reason, objective clinical assessments were extended by patient -reported outcome measures.The most common generic questionnaires, the Medical Outcome Study Short Form -36 (SF -36) 3 INTRODUCTION Chronic limb ischemia has an adverse effect on quality life. 1 Evaluation outcomes peripheral arterial disease (PAD) based parameters does not allow for a reliable assessment pain...

10.20452/pamw.4455 article EN Polskie Archiwum Medycyny Wewnętrznej 2019-02-22

In a double-blind cross-over study 20 mg of aspirin or placebo were administered to 18 patients with respiratory atopy without eczema and 12 healthy controls. Mean bleeding time before administration either was on average about 1 min. longer in atopics than the controls, this difference significant (p 0.05). Atopics' platelets also aggregated less well response arachidonic acid comparison On contrary, no platelet aggregability detected PAF-acether alone combination subthreshold, synergistic...

10.1007/978-3-0348-7451-9_12 article EN Birkhäuser Basel eBooks 1987-01-01
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