A5103128150- Circular RNAs in diseases
- Plant Molecular Biology Research
- Plant Stress Responses and Tolerance
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Gastric Cancer Management and Outcomes
- Genetic Mapping and Diversity in Plants and Animals
- Plant responses to water stress
- Plant Reproductive Biology
- Plant nutrient uptake and metabolism
- Nuclear Receptors and Signaling
- RNA modifications and cancer
- Plant Gene Expression Analysis
- Cancer Mechanisms and Therapy
- Insect-Plant Interactions and Control
- Rice Cultivation and Yield Improvement
- Plant biochemistry and biosynthesis
- FOXO transcription factor regulation
- Cardiac tumors and thrombi
- Gallbladder and Bile Duct Disorders
- Photosynthetic Processes and Mechanisms
- Sarcoma Diagnosis and Treatment
- Lipid metabolism and biosynthesis
- Vascular Malformations and Hemangiomas
- Remote Sensing in Agriculture
Shanghai Agrobiological Gene Center
2025
Xuzhou Medical College
2021-2024
Huazhong Agricultural University
2012-2023
National Cheng Kung University
2018
Plant responses to abiotic stresses are coordinated by arrays of growth and developmental processes. Indole-3-acetic acid (IAA) abscisic (ABA) play critical roles in programmes environmental responses, respectively, through complex signalling metabolism networks. However, crosstalk between the two phytohormones stress remains largely unknown. Here, it is reported that a GH3 family gene, OsGH3-2, encoding an enzyme catalysing IAA conjugation amino acids, involved modulation ABA level...
Circular RNAs (circRNAs) play important roles in cancer progression and metabolism regulation. Serine/glycine supports the growth of cells by contributing to their anabolic demands epigenome as well regulating redox state. However, role circRNA regulation serine/glycine has not been elucidated.Microarray analysis was used screen differentially expressed novel circRNAs. qRT-PCR FISH were utilized analyzed expression circMYH9. CCK8, colony formation FACS analyze proliferation colorectal (CRC)...
Summary Submergence and drought are major limiting factors for crop production. However, very limited studies have been reported on the distinct or overlapping mechanisms of plants in response to two water extremes. Here we report an ETHYLENE OVERPRODUCER 1 ‐like gene ( O s ETOL 1) that modulates differentially submergence tolerance rice ryza sativa L.). Two allelic mutants showed increased resistance stress at panicle development stage. Interestingly, exhibited a significantly slower growth...
High temperatures cause huge yield losses in rice. Heat-shock factors (Hsfs) are key transcription which regulate the expression of heat stress-responsive genes, but natural variation and functional characterization Hsfs have seldom been reported. A significant response locus was detected via a genome-wide association study (GWAS) using green leaf area as an indicative trait. miniature inverted-repeat transposable element (MITE) promoter candidate gene, HTG3 (heat-tolerance gene on...
Abstract Background Circular RNAs (circRNAs) play important roles in the occurrence and development of cancer chemoresistance. DNA damage repair contributes to proliferation cells resistance chemotherapy-induced apoptosis. However, role circRNAs regulation needs clarification. Methods RNA sequencing analysis was applied identify differentially expressed circRNAs. qRT-PCR conducted confirm expression hsa_circ_0007919, CCK-8, FCM, single-cell gel electrophoresis IF assays were used analyze...
Abstract Background Due to the great heterogeneity of gastric cancer (GC), prognosis patients within a stage is very different. Therefore, it necessary identify high risk factors for postoperative recurrence and metastasis take appropriate therapeutic strategies improve patients. In this study, we aimed explore prognostic significance preoperative serum carcinoembryonic antigen (CEA), carbohydrate 19 − 9 (CA19-9) 72 4 (CA72-4) in with I, II III GC who underwent radical gastrectomy. Methods A...
ABSTRACT Elucidating the mechanisms underlying heat tolerance in rice ( Oryza Sativa . L) is vital for adapting this crop to rising global temperature while increasing yields. Here, we identified a mutant, high 1 htt1 ), with survival rates under stress. HTT1 encodes chloroplast‐localized stearoyl‐acyl carrier protein (ACP) desaturase involved biosynthesis of unsaturated fatty acids, converting C18:0 C18:1 acid. Overexpression and knockout lines provided evidence that negatively regulates...
Self-occlusions are common in rice canopy images and strongly influence the calculation accuracies of panicle traits. Such interference can be largely eliminated if panicles phenotyped at 3D level. Research on phenotyping has been limited. Given that existing modeling techniques do not focus specified parts a target object, an efficient method for large numbers plants is lacking. This paper presents automatic nondestructive modeling. The proposed integrates shoot reconstruction with shape...
Transcription factors (TFs) play essential roles during plant development and response to environmental stresses. However, the relationships among transcription factors, cis-acting elements target gene expression under endo- exogenous stimuli have not been systematically characterized.Here, we developed a series of bioinformatics analysis methods infer transcriptional regulation by using numerous data from abiotic stresses hormones treatments. After filtering profiles TF-encoding genes, 291...
Although circular RNAs (circRNAs) have recently garnered interest as disease markers, they been relatively poorly studied a biomarker in colorectal cancer (CRC). In this study, we aimed to screen the exosome-derived circRNAs CRC and explore their potential diagnostic prognostic biomarkers of Exosomes were extracted from plasma using kit validated by immunoblotting, transmission electron microscopy, particle size analysis. The microarray datasets employed identify differentially-expressed...
Abstract CircRNAs are abnormally expressed in various cancers and play an important role the occurrence development of cancers. However, their biological functions underlying molecular mechanisms pancreatic cancer (PC) metastasis incompletely understood. Differentially circRNAs were identified by second‐generation transcriptome sequencing three pairs PC tissues adjacent tissues. The expression prognostic significance hsa_circ_0007919 evaluated qRT‐PCR Kaplan–Meier survival curves. Gain‐...
Abscisic acid (ABA) is a critical phytohormone that regulates multiple physiological processes including plant growth and stress tolerance. The core ABA signaling pathway has been well established, but genetic variations mediating responses remain largely unknown. In this study, we performed genome-wide association study (GWAS) to identify loci genes associated with sensitivity (reflected by seed germination inhibition ABA) in panel of 425 rice accessions. assay revealed Aus indica had...