A5103169211- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Hepatitis C virus research
- Renal Transplantation Outcomes and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Radiation Dose and Imaging
- Advanced Radiotherapy Techniques
- Diabetes and associated disorders
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Xenotransplantation and immune response
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Thyroid Disorders and Treatments
- Organ Donation and Transplantation
- Radiation Therapy and Dosimetry
- Vascular anomalies and interventions
- Colorectal Cancer Treatments and Studies
- Hydrology and Drought Analysis
- Pancreatic function and diabetes
- Lung Cancer Treatments and Mutations
- Vascular Procedures and Complications
- Oral and Maxillofacial Pathology
- Tree Root and Stability Studies
- Hydropower, Displacement, Environmental Impact
- Integrated Water Resources Management
Methodist University Hospital
2017-2022
Saint Louis University
2016-2022
University of Tennessee Health Science Center
2019-2022
Methodist University
2019
Royal Surrey County Hospital
2012
Analysis and Monitoring of Environmental Risk
2012
University of Rochester Medical Center
2008
Fundación Juan March
2008
Royal Victoria Hospital
2004-2006
McGill University
2004-2006
Obesity-related insulin resistance correlates with type I interferon–driven activation and expansion of intrahepatic T cells. See the related Focus by Ma et al .
Our aim was to evaluate the safety of transplanting kidneys from HCV-infected donors in HCV-uninfected recipients. Data collected 53 recipients a single center, observational study included donor and recipient characteristics, liver kidney graft function, new infections de novo donor-specific antibodies renal histology. Treatment with direct-acting antiviral regimen initiated when HCV RNA detected. The mean ± SD age 11 years, 34% were female, 19% 79% white African American, respectively....
Twenty-eight thyrotoxic patients were treated with propranolol. In seven the drug had to be discontinued after one or two months, but in remaining 21 clinical improvement was observed. Serial studies and tests of thyroid function performed at monthly intervals showed that four thyrotoxicosis remitted all indices returned normal. A fifth patient shows distinct evidence remission 20-minute <sup>132</sup>I uptake falling normal, although free-thyroxine index remains slightly raised. It is...
SUMMARY The course of thyrotoxicosis treated with antithyroid drugs has been studied in detail 105 thyrotoxic patients. Each patient was seen at intervals 1–3 months over a period more than 4 years and thus an average thirty serial tests thyroid function were made on each patient. Forty‐three patients remitted after one drugs. In another forty‐three the disease either required operative treatment or still active start therapy. remaining nineteen fell into intermediate group. light variable...
Acute liver failure (ALF) is a rare illness with high mortality rate. The only favorable management emergent transplantation. About 13% of ALF cases have no clear etiology. Epstein-Barr virus (EBV)-associated accounts for less than 1% all cases, and seen mostly in adults younger 40 years. There are few EBV-associated elderly immunocompromised adults. We report case an immunocompetent 67-year-old woman caused by EBV infection that was treated orthotopic transplantation (OLT). diagnosis...
A report of inflammatory damage when islets come into contact with allogeneic blood prompted us to confirm the finding.Fresh handpicked human were incubated in group matched, nonsensitized blood. Destruction was quantified by assaying supernatants for proinsulin release and clot histology. The effect on global hemostasis assessed thromboelastography (TEG), heparin-bonded tubing used assess cellular counts. In separate experiments, heparin or Reopro (monoclonal anti-GpIIbIIIa). Islets also...
Abstract AIM: To determine the effect of fertility control on rate transmission bovine tuberculosis (Tb), caused by Mycobacterium bovis, in brushtail possums (Trichosurus vulpecula). METHODS: At two study sites with a history Tb infection resident possum population, sample adult male and female (n=50), determined palpation to be Tb-free, was surgically sterilised gonadectomy. A untreated Tb-free (n=54) served as controls. Each site trapped every 2 months over 3-year period, status...
For islet allotransplantation to become a therapy widely applicable patients with insulin-dependent diabetes, it will be important avoid conventional immunosuppression and yet maintain long-term rejection-free survival. This possibility was tested in large-animal model using mixed allogeneic chimeras established total lymphoid irradiation (TLI) donor-specific bone marrow transplantation (BMTX). Four recipient sex-mismatched DLA class II-matched English springer spaniels became chimeric after...
Immunological unresponsiveness of T cells to alloantigen can be induced by intrathymic injection donor-specific antigen in small-animal models. Intrathymic tolerance vascularized grafts large animals has not previously been reported.Thirty-two dogs were allocated into dog leukocyte DP locus allele (class II)-matched donor-recipient pairs. Female recipients paired with male donors. Tissue typing was based on restriction fragment length polymorphism. Recipients given 18 Gy total lymphoid...
Background The utility of ex vivo Magnetic resonance imaging proton density fat fraction (MRI-PDFF) in donor liver quantification is unknown. Purpose To evaluate the diagnostic accuracy and predicting early allograft dysfunction (EAD) MRI-PDFF measurement deceased livers using histology as gold standard. Methods We performed Ex vivo, 1.5 Tesla on 33 human before implantation, enroute to operating room. After exclusion 4 images (technical errors), 29 MRI were evaluable. Histology was...
SUMMARY A 39‐year‐old male developed painful ulceration of the glans penis following simultaneous pancreas and kidney transplantation for end‐stage renal failure complicating insulin‐dependent diabetes mellitus. Infection was excluded. Diversion pancreatic secretions away from urinary bladder into bowel resulted in healing.
Journal Article The revision of RP 91 on criteria for acceptability radiological (including radiotherapy) and nuclear medicine installations Get access K. Faulkner, Faulkner * 1Quality Assurance Reference Centre, North East Strategic Health Authority, Waterfront 4, Goldcrest Way, Newburn Riverside, Newcastle upon Tyne NE15 8NY, UK *Corresponding author: keith.faulkner@nhs.net Search other works by this author on: Oxford Academic PubMed Google Scholar J. F. Malone, Malone 2Trinity Centre...
Background &amp; Aim Men have a higher prevalence of liver disease. Liver myeloid cells can regulate tissue inflammation, which drives progression We hypothesized that sex alters the responsiveness cells, predisposing men to severe inflammation. Methods Luminex was done on plasma from Hepatitis B Virus infected patients undergoing nucleoside analogue cessation in 45 male and female patients. collected immune sinusoids uninfected livers 53 donors. Multiparametric flow cytometry used...
Journal Article Practical application of suspension criteria scenarios: radiotherapy Get access I.-L. Lamm, Lamm * 1Medical Radiation Physics, Lund University, Lund, Sweden *Corresponding author: inger-lena.lamm@med.lu.se Search for other works by this author on: Oxford Academic PubMed Google Scholar P. Horton, Horton 2Department Medical Royal Surrey County Hospital, Guildford, UK W. Lehmann, Lehmann 3University Hospital Saarland, Homburg, Germany S. Lillicrap 4University Bath, Protection...
In 2007, the European Commission (EC) commissioned a group of experts to undertake revision Report Radiation Protection (RP 91) ‘Criteria for acceptability radiological (including radiotherapy) and nuclear medicine installations’ written in 1997( 1). The revised draft report was submitted EC 2010, who issued it public consultation. has same consider comments consultation further improvement report. intends publish final under its Series as RP 162. This paper describes background selection...