A5026978590- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Renal Transplantation Outcomes and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Organ Donation and Transplantation
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Renal and Vascular Pathologies
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- COVID-19 Impact on Reproduction
- Transplantation: Methods and Outcomes
- Pain Management and Opioid Use
- Cytomegalovirus and herpesvirus research
- Neurological Complications and Syndromes
- Vascular anomalies and interventions
- Migration, Health and Trauma
- Anesthesia and Pain Management
- Medical Imaging and Pathology Studies
- Opioid Use Disorder Treatment
- Advanced Radiotherapy Techniques
- Amoebic Infections and Treatments
- Tuberous Sclerosis Complex Research
- Central Venous Catheters and Hemodialysis
- Potassium and Related Disorders
SUNY Downstate Health Sciences University
2022
University of Connecticut
2019-2021
Hartford Hospital
2014-2021
Hartford Financial Services (United States)
2014-2020
Creative Research Enterprises (United States)
2018
Connecticut Children's Medical Center
2014
Westchester Medical Center
2008-2012
New York Medical College
2008-2011
Marymount University
2011
McGill University
2005-2006
Loco-regional therapies for cirrhotic patients with hepatocellular carcinoma (HCC) who are awaiting liver transplantation (OLT) attempt to prevent tumor progression. However, there is limited data regarding the efficacy of stereotactic body radiation therapy (SBRT) as loco-regional treatment.From 2006 2009, 27 HCC (AJCC I, II) listed OLT underwent SBRT. Thirty-nine lesions were treated and assessed radiologically. Seventeen had OLT, explants analyzed 22 pathological evaluation.In a...
Abstract Injury due to cold ischaemia‐reperfusion (IR) represents a major cause of primary graft non‐function following human liver transplantation. This cellular response translates into dramatic decrease in intracellular ATP concentration during the ischaemic phase, thus sensitizing cells reperfusion shock. We postulated that IR‐induced damage might alterations secretory pathway, particularly at level endoplasmic reticulum (ER) function. Under these circumstances, ER triggers an adaptive...
The prevalence of substance use disorder in the liver transplantation (LT) population makes postoperative pain management challenging. We report our initial experience with a novel, comprehensive, multidisciplinary opioid avoidance pathway 13 LT recipients between January 2018 and September 2019. Patients received comprehensive pre‐LT education on by surgeon, pharmacist, psychologist at time listing. Immediately after LT, patients continuous incisional ropivacaine infusion, ketamine,...
We report the first case of a healthy 23-year-old female who underwent an interventional radiology-guided embolization hepatic adenoma, which resulted in gas forming liver abscess and septicemia by Clostridium paraputrificum .A retrospective review Clostridial abscesses was performed using PubMed literature search, we found 57 clostridial cases.The two most commonly reported species are C. perfringens septicum (64.9% 17.5% respectively).C. cases carried mortality 67.6% with median survival...
Background. The authors recently published their experience of recanalizing umbilical veins in deceased liver donors, with recanalized as vascular conduits for meso-Rex bypass procedures. They have since found to be an excellent, easy harvest conduit that can used multiple procedures and repair. Here, they report using this vessel reconstruction. Methods. them a total 5 Meso-Rex bypasses; pancreaticoduodenectomies; 1 left hepatic trisegmentectomy right portal vein (PV) resection...
Abstract Noncirrhotic hyperammonemia (NCH) is a rare but often fatal complication of solid organ transplantation. We present case wherein an infectious cause NCH was suspected following kidney transplantation (KT) and the patient promptly started on empirical antibiotic treatment which proved to be lifesaving. A 56‐year‐old Chinese woman with past medical history end‐stage renal disease secondary ischemic nephropathy cerebrovascular accident received from 52‐year‐old brain‐dead donor Kidney...
Pregnancy in solid organ transplant recipients carries numerous risks to the mother such as increased risk of rejection, gestational diabetes mellitus, and preeclampsia. The developing fetus is subjected birth defects, preterm delivery, low weight. Typically, these can be managed through intensive, multidisciplinary prenatal care a proper immunosuppressive regimen. In setting however, little data are available suggest safe effective treatment acute cellular antibody-mediated or mixed...
Postoperative pain is a common complication of laparoscopic living-donor nephrectomies (LLDNs).To determine whether intravenous (IV) acetaminophen administration post-LLDN influenced length stay (LOS) when used for management.This single-center, retrospective study compared patients undergoing LLDN who had received IV control versus those did not between June 1, 2011, and November 30, 2015. Patient LOS, 30-day readmissions, frequency assessments, patient-reported scores, opioid were...
Abstract The clinical course and outcomes of immunocompromised patients, such as transplant recipients, with COVID‐19 remain unclear. It has been postulated that a substantial portion the disease burden seems to be mediated by host immune activation severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Herein, we present simultaneous heart‐kidney (SHKT) recipient who was hospitalized for management failure from volume overload complicated thrive, multiple opportunistic infections,...
To the Editor: Our knowledge about effects of COVID-19 on solid organ transplant (SOT) population is characterized by remarkable heterogeneity in treatment and outcomes SOT recipients infected with SARS-CoV-2. As one earliest hotspots United States, we present our 16 (13 kidney, 2 liver, 1 simultaneous heart-kidney) between March 30, 2020, May 7, at center (Institutional Review Board-approved database, HHC-2020-0124). Table provides case summaries study population. Ten patients were alive...
Background: Impaired glucose regulation posttransplantation can affect allograft survival and may lead to the development of posttransplant diabetes mellitus (PTDM). Objectives: The primary purpose this study is assess difference in insulin burden between liver transplant patients who develop PTDM do not. Methods: This was a single-center, retrospective study. Adult recipients transplanted January 1, 2005, August 2013, were included. defined as: (1) use an oral antihyperglycemic agent for...
Cryopreserved vein allografts (cadaveric vein) have emerged as an option for arteriovenous graft reconstruction; however, indications their use in hemodialysis access remains to be clearly defined. Observations from our own experience suggested that cadaveric grafts (CVGs) provide good outcomes, particularly patients with a history of infection, recurrent failure and advanced age.This is 10-year retrospective study. Primary outcomes were (1) identify characteristics specific this patient...
The number of patients on the liver transplant wait list is steadily increasing with no corresponding rise in grafts suitable for transplantation. There an trend dying or being removed from because deterioration. Over preceding years, use marginal transplantation has been driven by critical shortage donor organs. Data show that this organs resulted favorable outcomes.1 A 41-year-old female patient underwent orthotopic acute failure. graft was obtained a 68-year-old brain-dead donor....
Abstract Cytomegalovirus (CMV) is a significant cause of morbidity in kidney transplant recipients (KTR). Historically at our institution, KTR with low and intermediate CMV risk received 6 months valganciclovir if they lymphocyte depleting induction therapy. This study evaluates choice duration prophylaxis based on donor (D) recipient (R) serostatus the incidence post‐transplant viremia (D‐/R‐) (R+) receiving lymphocyte‐depleting A protocol utilizing valacyclovir for 3 D‐/R‐ R+ was...
Post-transplant lymphoproliferative disorder (PTLD) is an uncommon, but well-described complication after liver transplantation. Most recently, Hepatitis C virus (HCV) has been implicated in the development of PTLD. A HCV-negative 62-year-old man with autoimmune hepatitis received a HCV nucleic acid amplification test-positive graft from 73-year-old brain-dead donor (D+/R-). After his recovery operation, patient was treated for and achieved undetectable viral load. He readmitted 6 months...