- Analytical chemistry methods development
- Pharmaceutical and Antibiotic Environmental Impacts
- Toxic Organic Pollutants Impact
- Environmental Toxicology and Ecotoxicology
- Analytical Chemistry and Chromatography
- Effects and risks of endocrine disrupting chemicals
- Metabolomics and Mass Spectrometry Studies
- Electrochemical Analysis and Applications
- Advanced Chemical Sensor Technologies
- Cannabis and Cannabinoid Research
- Chemical and Physical Properties in Aqueous Solutions
- Heavy metals in environment
- Cultural Heritage Materials Analysis
- Pesticide Residue Analysis and Safety
- Forensic Toxicology and Drug Analysis
- Conservation Techniques and Studies
- Mercury impact and mitigation studies
- Mass Spectrometry Techniques and Applications
- Building materials and conservation
- Microplastics and Plastic Pollution
- Analytical Chemistry and Sensors
- Health, Environment, Cognitive Aging
- Radioactive element chemistry and processing
- Water Treatment and Disinfection
- Aquaculture Nutrition and Growth
University of the Basque Country
2015-2024
Marine Research Centre
2017-2021
BioCruces Health research Institute
2020-2021
European Commission
1996-1998
Joint Research Center
1997
Joint Research Centre
1996
Belgian Nuclear Research Centre
1996
The evolution of major cannabinoids and terpenes during the growth Cannabis sativa plants was studied. In this work, seven different were selected: three each from chemotypes I III one chemotype II. Fifty clones mother plant grown indoors under controlled conditions. Every week, variety cut dried, leaves flowers analyzed separately. Eight via HPLC-DAD, 28 quantified using GC-FID verified GC-MS. plants, as defined by tetrahydrocannabinolic acid/cannabidiolic acid (THCA/CBDA) ratio, clear...
This review evaluates the state of art suspect and non-target screening techniques including sampling, sample treatment, instrumental analysis, data processing an examination recent applications in xenobiotics' environmental occurrence.
The optimisation of focused ultrasound extraction and supercritical fluid volatile oils cannabinoids from marihuana has been accomplished by experimental design approach. On the one hand, method compounds was studied based on cyclohexane isopropanol solvent mixtures, instrumental variables. optimal working conditions were finally fixed at isopropanol/cyclohexane 1:1 mixture, cycles (3 s −1 ), amplitude (80%) sonication time (5 min). other optimised in order to obtain a deterpenation plant...
A high performance liquid chromatography coupled to tandem mass spectrometry (HPLC‐MS/MS) method for simultaneous quantification of Δ9‐tetrahydrocannabinol (THC), its two metabolites 11‐hydroxy‐Δ9‐tetrahydrocannabinol (11‐OH‐THC) and 11‐nor‐9‐carboxy‐Δ9‐tetrahydrocannabinol (THC‐COOH), four additional cannabinoids (cannabidiol (CBD), cannabigerol (CBG), tetrahydrocannabivarin (THCV), cannabinol (CBN)) in 1 mL human urine plasma was developed validated. The hydrolysis process studied ensure...
This review describes a wide variety of analytical approaches for the assessment human exposure to organic chemicals associated with plastic additives, focusing on works published in last decade plasticisers, bisphenols, flame retardants and antioxidants. Physiologically based extraction tests serve as preliminary in-vitro assays determine bioaccessibility these compounds from micro/nanoplastics body fluids gastrointestinal tract, skin, or lung. Whenever plastic-laden become bioavailable,...
Abstract Marine Porifera host diverse microbial communities, which influence metabolism and fitness. However, functional relationships between sponge microbiomes metabolic signatures are poorly understood. We integrate microbiome characterization, metabolomics predicted functions of four coexisting Mediterranean sponges – Petrosia ficiformis , Chondrosia reniformis Crambe crambe Chondrilla nucula . Microscopy observations reveal anatomical differences in densities. Microbiomes exhibit strong...
Abstract In this study, supercritical fluid extraction has been successfully applied to a sequential fractionation of fatty acids and polyphenols from wine wastes (2 different vitis vinifera grapes). To aim, in 1st step just were extracted 2nd one the polyphenols. The variables that affected efficiency separately optimized both steps following an experimental design approach. effect temperature flow, pressure, time thoroughly evaluated for acids, whereas addition methanol was also considered...
This work reports important advances in the study of magnetic nanoparticles (MNPs) related to their application different research fields such as hyperthermia. Nanotherapy based on targeted could become an attractive alternative conventional oncologic treatments it allows a local heating tumoral surroundings without damage healthy tissue. RGD-peptide-conjugated MNPs have been designed specifically target α V β 3 receptor-expressing cancer cells, being bound RGD peptides by “click chemistry”...