A5049219433- Actinomycetales infections and treatment
- Mycobacterium research and diagnosis
- Infectious Diseases and Mycology
- Milk Quality and Mastitis in Dairy Cows
- Probiotics and Fermented Foods
- Burkholderia infections and melioidosis
- Mycorrhizal Fungi and Plant Interactions
- Microbial infections and disease research
- Fungal Infections and Studies
- Bacterial Identification and Susceptibility Testing
- Microbial Metabolism and Applications
- Immune Response and Inflammation
National Institute for Communicable Disease Control and Prevention
2023-2024
Lanzhou Institute of Husbandry and Pharmaceutical Sciences
2021-2023
Chinese Academy of Agricultural Sciences
2021-2023
Center for Disease Control
2023
Nocardia, a rare but potentially fatal pathogen, can induce systemic infections with diverse manifestations. This study aimed to investigate the tissue and organ damage caused by Nocardia farcinica (N. farcinica) in mice via different infection routes, evaluate resulting host immune responses, assess its invasiveness brain tissue.
Streptococcus dysgalactiae is a major pathogen in bovine mastitis. The purpose of this study was to survey the prevalence, antimicrobial resistance, as well spread resistance and virulence-associated gene S. dysgalactiae.A total 60 strains were obtained from 830 milk samples Holstein cows with clinical Antimicrobial examined by disk diffusion method. virulence genes investigated PCR, agarose gel electrophoresis 16S rRNA sequencing.All isolates resistant tetracycline showed high level...
ABSTRACT Nocardia farcinica can cause a rare, yet potentially fatal, central nervous system infection. NbtS protein may be key virulence factor in N. infection of the brain. In this study, we investigated function virulence-associated microglial cells vitro and infected mice vivo . We explored interactions between (BV2 human clone 3), revealing that activates toll-like receptor 4-dependent MyD88-IRAK4-IRAK1 MAPK/nuclear kappa B (NF-κB) pathways, significantly enhancing pro-inflammatory...
TwoGram-stain-positive and rod-shaped actinomycetes (strains CDC186
Nocardia is emerging as a common and easily neglected cause of both healthcare- occupation-associated infections worldwide, however, human vaccines for prevention are not yet available. In this study, we aimed to evaluate the immunoprotective effect NFA47630 protein, secreted protein abundant in N. farcinica IFM10152 supernatant.
Abstract Nocardia farcinica , one of the most common etiological pathogens nocardiosis in pulmonary infection, usually causes severe disseminated diseases immunocompromised individuals. To date, there is a lack rapid and reliable diagnostic tools for detection N. clinical laboratories. In present study, we reported development rapidity, simplicity, high specificity real-time fluorescence recombinase-aided amplification (RT-RAA) assay . RT-RAA technique was developed to amplify specific gene...