A5032554527- Tryptophan and brain disorders
- Cerebrospinal fluid and hydrocephalus
- Neural dynamics and brain function
- Bipolar Disorder and Treatment
- Functional Brain Connectivity Studies
- Epigenetics and DNA Methylation
- Neuroscience of respiration and sleep
- Treatment of Major Depression
- Memory and Neural Mechanisms
- Diet and metabolism studies
- Traumatic Brain Injury Research
Second Xiangya Hospital of Central South University
2022-2024
Central South University
2022-2024
Major depressive disorder is one of the most common mental health conditions. Meningeal lymphatics are essential for drainage molecules in cerebrospinal fluid to peripheral immune system. Their potential role depression-like behaviour has not been investigated. Here, we show mice, sub-chronic variable stress as a model impairs meningeal females but males. Manipulations regulate sex difference susceptibility stress-induced depression- and anxiety-like behaviors well alterations medial...
Abstract Major depressive disorder (MDD) is a pressing global health issue. Its pathogenesis remains elusive, but numerous studies have revealed its intricate associations with various biological factors. Consequently, there an urgent need for comprehensive multi-omics resource to help researchers in conducting data analysis MDD. To address this issue, we constructed the MDDOmics database (Major Depressive Disorder Omics, (https://www.csuligroup.com/MDDOmics/), which integrates extensive...
Objective: Electroencephalogram (EEG) can provide a basis for the auxiliary diagnosis of generalized anxiety disorder (GAD). The purpose this study was to investigate abnormality resting state EEG in GAD patients. Methods: We extracted absolute and relative power spectrum features from 10 patients healthy controls (HC). K-nearest neighbor (KNN), linear discriminant analysis (LDA), support vector machine (SVM) were used accurately identify HC studied correlation between scores 7 items scale...