A5025559531- Granular flow and fluidized beds
- Advanced Radiotherapy Techniques
- Landslides and related hazards
- Medical Imaging Techniques and Applications
- Fluid Dynamics Simulations and Interactions
- Lung Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Pelvic floor disorders treatments
- Radiomics and Machine Learning in Medical Imaging
- Geotechnical Engineering and Soil Mechanics
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Geotechnical and Geomechanical Engineering
- Advanced X-ray and CT Imaging
- Soil and Unsaturated Flow
- Microtubule and mitosis dynamics
- Ocular Oncology and Treatments
- Soil Mechanics and Vehicle Dynamics
- Nuclear Physics and Applications
- High-Velocity Impact and Material Behavior
- Rock Mechanics and Modeling
- Liver Disease Diagnosis and Treatment
- Ultrasound and Hyperthermia Applications
- Inhalation and Respiratory Drug Delivery
Atlantia (Italy)
2024
Politecnico di Milano
2014-2023
Centro Diagnostico Italiano
2015-2019
University of Messina
2019
Radiation Oncology Associates
2019
Azienda Ospedaliera San Gerardo
2006-2016
Fondazione IRCCS Istituto Nazionale dei Tumori
2016
Kyoto University
2016
Herlev Hospital
2015
University of Copenhagen
2015
A multidisciplinary and multi-institutional working group applied the Failure Mode Effects Analysis (FMEA) approach to assess risks for patients undergoing Stereotactic Body Radiation Therapy (SBRT) treatments lesions located in spine liver two CyberKnife® Centres. The various sub-processes characterizing SBRT treatment were identified generate process trees of both planning delivery phases. This analysis drove identification subsequent scoring potential failure modes, together with their...
Introduction Image-guided robotic radiosurgery is an emerging minimally-invasive treatment option for trigeminal neuralgia (TN). Our group has treated 560 cases up to date, and report here the clinical outcomes of 387 treatments with three years follow-up. This study represents largest single-center experience on CyberKnife TN so far reported. Methods was offered patients drug-resistant TN, after failure other or refusal invasive procedures. A second a poor response first recurrent pain....
Objective. Hyperferritinemia is frequent in chronic liver diseases of any cause, but the extent to which ferritin truly reflects iron stores variable. In these patients, both and fat are found variable amount association. Liver biopsy often required quantify iron, sampling variability invasiveness limit its use. We aimed assess single breath-hold multiecho magnetic resonance imaging (MRI) for simultaneous lipid quantification patients with hyperferritinemia. Material methods. compared MRI...
Abstract During heating (loading characterised by a progressive increase in strain rate) and cooling decrease numerical tests, performed using Discrete Element codes, granular materials experience phase transition phenomena, named this paper ‘dry liquefaction’ (when from solid the material starts behaving like fluid) resolidification’ (freezing, when fluid solid). The aim of consists reproducing phenomena hardening visco‐elastic‐plastic model based on critical state concept kinetic theories...
Summary The numerical simulation of rapid landslides is quite complex mainly because constitutive models capable simulating the mechanical behaviour granular materials in pre‐collapse and post‐collapse regimes are still missing. goal this paper to introduce a model capturing response dry flows from quasi‐static dynamic conditions, particular when material experiences sort solid‐to‐fluid phase transition. An ideal assembly identical spheres under simple shear conditions considered. In model,...
Abstract In mountain regions, rockfall is a very widespread natural hazard, difficult to be numerically simulated, from the initial detachment of block its impact on natural/artificial strata. When rock impacts granular stratum, interaction dominated by inertial effects and severely affected mass, shape, velocity magnitude/direction, soil geomechanical properties. The kinematic description response during requires complex time-consuming numerical modeling approaches. Moreover, these...
Abstract The assessment of the time evolution impact force exerted by dry flowing masses on rigid obstacles is mandatory for dynamic design sheltering structures and evaluation vulnerability existing structures. In this paper, results an extensive numerical campaign performed employing a discrete element method (DEM) code are presented role different geometrical factors (flow length, height front inclination) state parameters (porosity velocity) force–time investigated. process studied to...
SUMMARY In this paper, the results of an oedometric numerical test campaign, performed by means a 3D Discrete Element Code on idealised cemented granular cylindrical specimens, are illustrated. The microstructure taken into account is characterised following: (i) rigid grains bonded to one another; (ii) high void ratio; and (iii) two different families voids: micro macro‐voids. compaction process developing within as well localization along tabular zones pure compressive deformation...
Summary In this paper, steady‐state conditions for ideal monodisperse dry granular materials are both theoretically and numerically analysed. A series of discrete element (DEM) numerical simulations have been performed on a periodic cell by imposing stress paths characterized different Lode angles, pressures, deviatoric strain rates. The dependence the material response inertial number loading path has discussed in terms void ratio, fabric, temperature. DEM results finally compared with...
Many natural phenomena (rock or snow avalanches, and debris flows) as well industrial processes are characterized by the flow of solid particles. A key issue in development a numerical tool for study this problem is implementation suitable constitutive model, capable capturing complex rheological behaviour granular material wide range strain rates. At micro-scale level, grains interacts enduring frictional contacts nearly instantaneous collisions. The first mechanism prevails at low shear...
Abstract The dynamic interaction between granular flowing masses and rigid obstacles is a complex phenomenon characterised by both large displacements high strain rates. In case the mass modelled as continuum, its numerical simulation requires advanced computational tools constitutive relationships capable of predicting mechanical behaviour same material under fluid solid regimes. this paper, authors employed open‐source ANURA3D code, based on Material Point Method (MPM), multi‐regime model....