A5001302952- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Endodontics and Root Canal Treatments
- Dental materials and restorations
- Pregnancy and preeclampsia studies
- Pregnancy and Medication Impact
- Drug-Induced Hepatotoxicity and Protection
- Dental Radiography and Imaging
- Oral microbiology and periodontitis research
- Crystallography and molecular interactions
- Nanoparticle-Based Drug Delivery
- Criminal Law and Evidence
- Nanoparticles: synthesis and applications
- Sinusitis and nasal conditions
- Biosensors and Analytical Detection
- Dental Anxiety and Anesthesia Techniques
- Judicial and Constitutional Studies
- Iron Metabolism and Disorders
- Chemokine receptors and signaling
- Stress Responses and Cortisol
- Melanoma and MAPK Pathways
- Cancer Research and Treatments
- Electrolyte and hormonal disorders
- Analytical Methods in Pharmaceuticals
- Cardiovascular Disease and Adiposity
Sichuan University
2006-2020
Jilin Medical University
2020
Qingdao University
2016
Affiliated Hospital of Qingdao University
2016
University College Dublin
2013
State Key Laboratory of Oral Diseases
2012
Beijing Hospital
2008
University of Mississippi Medical Center
2002
While protein coronas (PCs) are an important barrier in the clinical application of nanomedicines, specific effects PCs on nanoparticles (NPs) vivo unclear. Herein, we demonstrated that from sources greatly influenced active targeting capacities transferrin-modified NPs (Tf-NPs). Compared to healthy volunteers, plasma patients with nonsmall cell lung cancer (NSCLC) decreased A549 uptake Tf-NPs a greater degree. The PC proteome revealed this difference may be mediated by certain proteins...
Many studies have shown the influence of protein corona (PC) on active targeting capability ligand-modified nanoparticles; however, clinical status PC composition and capacity is rarely discussed. In this study, when transferrin-modified PEGylated polystyrene nanoparticles (Tf-PNs) intravenously injected into mice with non-small cell lung cancer (NSCLC) comorbid type 2 diabetes mellitus (T2DM), more Tf-PNs accumulated in tumor tissue than those NSCLC model mice. This indicated that derived...
To evaluate human pulp tissue response following direct capping with a self-etching adhesive: Clearfil SE BOND (SB).Forty-five sound teeth from 20 subjects were used. Forty-one had their mechanically exposed at the base of Class 1 cavity preparation and divided into two groups: group 1, capped SB (n = 21), 2, calcium hydroxide cement (CH) 20). Four maintained intact as an untreated control group. After 7, 30 90 days, respectively, 15 extracted processed for light microscopic examination....
Inflammation plays an important role in cerebral ischemia reperfusion, which can cause severe damage to the brain and may lead hemorrhage transformation. p38-mitogen-activated protein kinase (p38mapk) has been implicated etiology of a number diseases because it is inflammation, but comparatively little research carried out into its reperfusion. We investigated expression p38mapk reperfusion gain better understanding potential hemorrhagic transformation (HT). One hundred rats were randomly...
ET-26-HCl, a novel anaesthetic agent with promising pharmacological properties, lacks extensive studies on pharmacokinetics and disposition in vitro vivo . In this study, we investigated the metabolic stability, metabolite production plasma protein binding (PPB) of ET-26-HCl along its tissue distribution, excretion animals after intravenous administration. Ultra-high performance liquid chromatography–tandem quadrupole time-of-flight mass spectrometry identified total eight new metabolites...
Background: Community health centres (CHCs) are an important component of the system in Mali and China. Despite patient support commitment from authorities, management quality care these structures need to be improved. This research aimed compare style relevant boards with users' satisfaction pertaining CHC services China.Method: Between September 2009-January 2010, a study was conducted eight CHCs 16 A total 480 householders, [60 (Mali) 320 (China)]; 24 committee members 48 (China) were...
Abstract A rapid and sensitive High-Performance Liquid Chromatography-tandem Mass Spectrometry (HPLC/MS/MS) method for determining apremilast in beagle dog plasma urine samples was developed validated using clopidogrel as the internal standard (IS). Apremilast extracted from by liquid–liquid extraction methyl tert-butyl ether. Chromatographic separation performed a C 8 column with gradient elution mobile phase containing methanol 0.1% formic acid. Quantification achieved multiple reaction...
Abstract BackgroudThe associating liver partition and portal vein ligation (ALPPS) technique is a promising strategy for unresectable tumors without sufficient future remnants (FLRs). Criticism has focused on its stimulation of tumor growth. This study explores the effect corosolic acid (CA) inhibiting growth compromising ALPPS-induced regeneration investigates possible mechanism.MethodsThe ALPPS procedure was performed in Sprague-Dawley rats with orthotopic cancer. Blood, FLR samples...