Abdulsamad Alsalahi

ORCID: 0000-0002-2967-0556
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About
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Research Areas
  • Polysaccharides Composition and Applications
  • COVID-19 and Mental Health
  • Forensic Toxicology and Drug Analysis
  • Natural Antidiabetic Agents Studies
  • Psychological Well-being and Life Satisfaction
  • Alcohol Consumption and Health Effects
  • Plant Toxicity and Pharmacological Properties
  • Coconut Research and Applications
  • Neurotransmitter Receptor Influence on Behavior
  • Posttraumatic Stress Disorder Research
  • Resilience and Mental Health
  • Identification and Quantification in Food
  • Regulation of Appetite and Obesity
  • Neuropeptides and Animal Physiology
  • Nigella sativa pharmacological applications
  • Diabetes and associated disorders
  • Polysaccharides and Plant Cell Walls
  • Computational Drug Discovery Methods
  • Fatty Acid Research and Health
  • Bioactive natural compounds
  • Plant-based Medicinal Research
  • Advanced Glycation End Products research
  • Machine Learning in Bioinformatics
  • Synthesis and Biological Activity
  • Ethnobotanical and Medicinal Plants Studies

Sana'a University
2020-2024

University of Malaya
2012-2022

Universiti Putra Malaysia
2020

Background: Several instruments are currently used to assess Coronavirus Disease 2019 (COVID-19) -induced psychological distress, including the 22-item Impact of Event Scale-Revised (IES-R). The IES-R is a self-administered scale post-traumatic stress disorder (PTSD). current study aimed examine construct validity IES-R, based on Rasch model, with COVID-19-related data, as well test multilevel within and among countries during pandemic crisis. Methods: A multi-country web-based...

10.3390/healthcare10101858 article EN Healthcare 2022-09-24

The COVID-19 pandemic, on a global scale, has prompted multifaceted challenges, including notable psychological toll the general population. This study uses mixed-method approach for nuanced exploration of these experiences. Using phenomenological strategy, qualitative responses from 999 participants were analyzed regarding their pandemic-induced anxiety and influence quarantine measures lives. Quantitative measures, revised Impact Event Scale (IES-R), patient health questionnaire-9 (PHQ-9),...

10.3390/healthcare11172418 article EN Healthcare 2023-08-29

Although the psychological impact of coronavirus disease 2019 (COVID-19) has been evaluated in literature, further research is needed, particularly on post-traumatic stress disorder (PTSD) and outcomes, needed. This study aims to investigate effect COVID-19 pandemic outcomes (depression, anxiety, insomnia). A cross-sectional using an online survey was conducted following instruments: Impact Event Scale-Revised (IES-R), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder...

10.1371/journal.pone.0277368 article EN cc-by PLoS ONE 2022-11-09

Cancer is one of the major health problems worldwide and its current treatments have a number undesired adverse side effects. Natural compounds may reduce these. Currently, few plant products are being used to treat cancer. In this study, goniothalamin, natural occurring styryl-lactone extracted from Goniothalamus macrophyllus, was investigated for cytotoxic properties against cervical cancer (HeLa), breast carcinoma (MCF-7) colon (HT29) cells as well normal mouse fibroblast (3T3) using MTT...

10.7314/apjcp.2012.13.10.5131 article EN cc-by Asian Pacific Journal of Cancer Prevention 2012-10-31

Background Ceratonia siliqua pods (carob) have been nominated to control the high blood glucose of diabetics. In Yemen, however, its antihyperglycemic activity has not yet assessed. Thus, this study evaluated in vitro inhibitory effect methanolic extract carob against α-amylase and α-glucosidase vivo glycemic such streptozotocin-nicotinamide induced diabetic rats. Methods 2,2-diphenyl-1-picrylhydrazyl (DPPH) Ferric reducing antioxidant power assay (FRAP) were applied evaluate carob....

10.7717/peerj.4788 article EN cc-by PeerJ 2018-05-23

The increasing prevalence of antimicrobial-resistant (AMR) bacteria in humans, animals, and the environment underscores necessity for a rapid, sensitive, specific method to identify resistance genes. Objectives: This study aims develop reliable detection tool identifying tetracycline-resistant gene tet(M) Enterococcus species using real-time loop-mediated isothermal amplification (RT-LAMP) assay. Real-time visualization through turbidimeter enabled precise estimation time-to-positivity...

10.3390/diagnostics15101213 article EN cc-by Diagnostics 2025-05-12

Hepato- and nephrotoxicity of Khat consumption ( Catha edulis Forskal) have been evoked. Therefore, this study was conducted to evaluate such possible hepatorenal toxicity in female male Sprague-Dawley rats (SD rats) focusing primarily on liver kidney. In addition, were investigated separately. Accordingly, forty-eight SD-rats (100–120 g) distributed randomly into four groups males (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...

10.1155/2012/829401 article EN Evidence-based Complementary and Alternative Medicine 2012-01-01

People consume Catha edulis (khat) for its euphoric effect, and type 1 diabetics have claimed that khat could reduce elevated levels of blood sugar. However, has been suggested to provoke diabetes mellitus through destruction pancreatic β-cells. This study investigated the effect an ethanolic extract on functions in (T1DM)-induced male Sprague-Dawley rats assess vitro cytotoxicity rat β-cells (RIN-14B). T1DM was induced a total 20 with single intraperitoneal injection 75 mg/kg...

10.1538/expanim.18-0057 article EN EXPERIMENTAL ANIMALS 2018-01-01

Background: Several instruments are currently used to assess the Coronavirus Disease 2019 (COVID-19) induced psychological distress, including 22-Items Impact of Event Scale-Revised (IES-R). The IES-R is a self-administered scale posttraumatic stress symptomology after traumatic event, measuring symptoms intrusion, avoidance, and hyperarousal as experienced in past seven days.Objectives: current study aimed examine construct validity based on Rasch Model with COVID-19 related data well test...

10.2139/ssrn.3815681 article EN SSRN Electronic Journal 2021-01-01

Cathinone, the main bioactive alkaloid of Catha edulis (khat), slightly increased blood sugar levels healthy animals, while its effect on diabetic animals has not yet been reported. This study investigated in vitro inhibition cathinone α-amylase and α-glucosidase as well vivo glycemic effects diabetes-induced rats. Rats were fed a high fat diet for five weeks, which then intraperitoneally injected with streptozotocin (30 mg/kg). Diabetic rats distributed randomly into control (DC, n = 5), 10...

10.1016/j.sjbs.2021.04.072 article EN cc-by-nc-nd Saudi Journal of Biological Sciences 2021-05-01

Abstract Background: Due to the limited research examining psychological impact of coronavirus disease 2019 (COVID-19), our study aims investigate effect COVID-19 pandemic on outcomes and assess differences between participants with without post-traumatic stress disorder (PTSD) as latent factors items. Methods: An online survey was conducted 999 participants. The Impact Event Scale-Revised (IES-R) assessed impact, while were measured by Patient Health Questionnaire-9 (PHQ-9), Generalized...

10.21203/rs.3.rs-854593/v1 preprint EN cc-by Research Square (Research Square) 2021-09-27
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