- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Cardiovascular and exercise physiology
- Sperm and Testicular Function
- Diabetes and associated disorders
- Neurobiology and Insect Physiology Research
- Ubiquitin and proteasome pathways
- Hemiptera Insect Studies
- RNA Research and Splicing
- Glycosylation and Glycoproteins Research
- Signaling Pathways in Disease
- Adipokines, Inflammation, and Metabolic Diseases
- Fibroblast Growth Factor Research
- Reproductive Biology and Fertility
- Cardiac Arrhythmias and Treatments
- Muscle activation and electromyography studies
- Atherosclerosis and Cardiovascular Diseases
- Pharmacological Effects and Assays
- Viral Infections and Immunology Research
- RNA and protein synthesis mechanisms
- Sports Performance and Training
- Acute Myocardial Infarction Research
- Pluripotent Stem Cells Research
- Reproductive Health and Technologies
- Erythrocyte Function and Pathophysiology
Chengdu Second People's Hospital
2024
Florida State University
2020-2024
Central South University
2017-2018
National Engineering Research Center of Human Stem Cells
2017
Thermo Fisher Scientific (Japan)
2000
Troponin C (TnC) is the Ca2+-sensing subunit of troponin that responsible for activating thin filaments in striated muscle, and turn regulating systolic diastolic contractile function cardiac muscle. Secondary structure vertebrate TnC mainly α-helices, with 9 helices named from N A-H. The N-helix a 12-residue-long α-helix located at extreme amino terminus protein only helical does not participate forming Ca2+-binding EF-hands. Evolutionarily, found mammalian species most other vertebrates...
A diploid genome is necessary for normal mammalian development, thus haploid parthenogenetic embryos undergo frequent self-diploidization during preimplantation development; however, the underlying mechanism unclear. In this study, time-lapse recording revealed that human parthenotes (HPs) via failed cytokinesis (FC) and endomitosis (EM). The frequencies of FC/EM were significantly higher in HPs than fertilized (26.3% vs. 1.6%, P < 0.01; 19.7% 0, 0.01), above 90% occurred at first cell cycle...
In this report, we establish a straightforward method for estimating the equilibrium constant creatine kinase reaction (CK Keq″) over wide but physiologically and experimentally relevant ranges of pH, Mg2+ temperature. Our empirical formula CK Keq″ is based on experimental measurements. It can be used to estimate [ADP] when below resolution measurements, typical situation because order micromolar concentrations in living cells may much lower many vitro experiments. Accurate prediction...
To evaluate the efficiency and safety of SperMagic medium on stimulating immotile spermatozoa in testicular sperm extraction (TESE) absolute asthenozoospermia, 96 patients with TESE 106 asthenozoospermia were enrolled this study. The motile detected 47 68 these assigned to control group. 49 34 stimulated medium. Patients treated by standard intracytoplasmic injection (ICSI). There no significant differences fertilisation, cleavage, implantation, pregnancy, live birth neonatal outcomes. does...
In this report, we establish a straightforward method for estimating the equilibrium constant CK reaction over wide but physiologically and experimentally relevant ranges of pH, Mg2+ temperature. Our empirical formula Keq” is based on experimental measurements. It can be used to estimate [ADP] when below resolution measurements, typical situation because order micromolar concentrations in living cells, may much lower many vitro experiments. Accurate prediction essential vivo studies cellular...