Xinyuan Zhang

ORCID: 0000-0002-2974-8392
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Nutritional Studies and Diet
  • Cardiovascular Health and Disease Prevention
  • Parkinson's Disease Mechanisms and Treatments
  • Magnesium in Health and Disease
  • Parathyroid Disorders and Treatments
  • Adsorption and biosorption for pollutant removal
  • Cardiovascular Health and Risk Factors
  • Functional Brain Connectivity Studies
  • Air Quality and Health Impacts
  • Heavy metals in environment
  • Cardiovascular Disease and Adiposity
  • Fungal Biology and Applications
  • Folate and B Vitamins Research
  • Blood Pressure and Hypertension Studies
  • Diet, Metabolism, and Disease
  • Aluminum toxicity and tolerance in plants and animals
  • Optical Imaging and Spectroscopy Techniques
  • Obesity, Physical Activity, Diet
  • Plant Stress Responses and Tolerance
  • Neural dynamics and brain function
  • Neuroscience and Neuropharmacology Research
  • Postharvest Quality and Shelf Life Management
  • Heart Rate Variability and Autonomic Control
  • Arsenic contamination and mitigation

Harvard University
2022-2025

Brigham and Women's Hospital
2022-2025

Jinan University
2025

Fudan University
2025

Huazhong University of Science and Technology
2025

Sichuan University
2025

Pennsylvania State University
2019-2024

Yale University
2024

Jiangsu Normal University
2024

Northeast Normal University
2024

Previous studies on the relationship between diabetes and arterial stiffness were mostly cross-sectional. A few longitudinal focused one single direction. Whether association is bidirectional remains unclear to date.To explore temporal fasting blood glucose (FBG) status.Included 14 159 participants of Kailuan study with assessment brachial-ankle pulse wave velocity (baPWV) from 2010 2015, free diabetes, cardiovascular cerebrovascular diseases, chronic kidney disease at baseline. FBG baPWV...

10.1161/circresaha.120.317950 article EN Circulation Research 2020-09-28

Arterial stiffness and blood pressure (BP) both increase with aging synchronously. Whether elevated BP results from thickening of arterial wall or vice versa is controversial in previous studies. This study included 17 862 participants without history myocardial infarction, stroke, atrial fibrillation flutter, cancer brachial-ankle pulse wave velocity (baPWV) measurements during 2010 to 2016. Age was calculated the self-reported birthdate first date baPWV examination. Mediation analyses were...

10.1161/hypertensionaha.118.12396 article EN Hypertension 2019-02-19

Per- and polyfluoroalkyl substances (PFAS) are widespread pollutants with demonstrated hepatotoxicity. Few studies have examined the association between PFAS fatty liver disease (FLD) risk in an adult population.

10.1016/j.jhepr.2023.100694 article EN cc-by-nc-nd JHEP Reports 2023-02-03

Importance Approximately 65% of adults in the US consume sugar-sweetened beverages daily. Objective To study associations between intake beverages, artificially sweetened and incidence liver cancer chronic disease mortality. Design, Setting, Participants A prospective cohort with 98 786 postmenopausal women aged 50 to 79 years enrolled Women’s Health Initiative from 1993 1998 at 40 clinical centers were followed up March 1, 2020. Exposures Sugar-sweetened beverage was assessed based on a...

10.1001/jama.2023.12618 article EN JAMA 2023-08-08

Although flavonoids have the potential to exert neuroprotective benefits, evidence of their role in improving survival rates among individuals with Parkinson disease (PD) remains lacking. We aimed prospectively study association between prediagnosis and postdiagnosis flavonoid intakes risk mortality PD identified from 2 large ongoing cohorts US men women.Included current analysis were 599 women Nurses' Health Study 652 Professionals Follow-Up who newly diagnosed during follow-up. Dietary...

10.1212/wnl.0000000000013275 article EN Neurology 2022-01-26

Abstract Background Studies regarding whether light to moderate alcohol consumption is associated with a lower risk of cardiovascular diseases (CVD) have generated mixed results. Further, few studies examined the potential impact on diverse disease outcomes simultaneously. We aimed prospectively study dose-response association between and CVD, cancer, mortality. Methods This included 83,732 adult Chinese participants, free CVD cancer at baseline. Participants were categorized into 6 groups...

10.1186/s12937-021-00671-y article EN cc-by Nutrition Journal 2021-02-01

A viologen-functionalized europium-based metal–organic framework, denoted as compound 1, has been synthesized solvothermally by employing 1,1′-bis(3,5-dicarboxyphenyl)-4,4′-bipyridinium dichloride (abbreviated H4bdcbpCl2). Compound 1 possesses a 2-fold parallel self-interpenetrating structure composed of two sets identical three-dimensional (3D) cationic frameworks with {4·84·12}2{42·82·102}{8}2 topology. The introduction tetracarboxylic group-decorated viologen derivative not only...

10.1021/acs.cgd.4c00765 article EN Crystal Growth & Design 2024-08-01

<h3>Importance</h3> Greater diet quality and physical activity level are associated with a lower risk of developing Parkinson disease (PD). However, information regarding the association between lifestyle behaviors survival after PD diagnosis remains limited. <h3>Objective</h3> To examine prediagnosis postdiagnosis overall all-cause mortality among individuals PD. <h3>Design, Setting, Participants</h3> This population-based cohort study analyzed male participants in Health Professionals...

10.1001/jamanetworkopen.2022.27738 article EN cc-by-nc-nd JAMA Network Open 2022-08-19

Agricultural sustainability is the foundation and a guarantee of sustainable human reproduction. The scientific assessment China's agricultural prerequisite for properly resolving conflict between short-term economic interests long-term ecological security. This paper uses emergy analysis method to estimate in China further calculates environmental cost green GDP. results show that yield rate (EYR) generally greater than 1. means more obtained relation renewable non-renewable inputs from...

10.3390/ijerph192416735 article EN International Journal of Environmental Research and Public Health 2022-12-13

Proteomics may discover pathophysiological changes related to hepatocellular carcinoma, an aggressive and lethal type of cancer with low sensitivity for early stage diagnosis.

10.1093/jnci/djae079 article EN JNCI Journal of the National Cancer Institute 2024-04-23

Freestanding nanomembranes fabricated by lift-off technology have been widely utilized in microelectromechanical systems, soft electronics, and microrobotics. However, a conventional chemical etching strategy to eliminate nanomembrane adhesion often restricts material choice compromises quality. Herein, we propose nanomembrane-on-graphene that leverages the weak van der Waals on graphene achieve scalable controllable release 3D construction of nanomembranes. This fragile allows for precise...

10.1021/acsnano.4c07589 article EN ACS Nano 2025-01-03

Volatile organic compounds (VOCs) are closely associated with the maturity and variety of strawberries. However, complexity VOCs hinders their potential application in strawberry classification. This study developed a novel classification workflow using VOC profiles machine learning (ML) models for precise fruit A comprehensive dataset was rapidly collected gas chromatography-ion mobility spectrometry (GC-IMS) from five varieties at four stages (n = 300) visualized through principal...

10.3390/foods14020169 article EN cc-by Foods 2025-01-08

Metabolic dysfunction associated steatotic liver disease (MASLD) has been with increased risks of all-cause and cardiovascular (CVD) mortality. Identification modifiable risk factors that may contribute to higher mortality could facilitate targeted intensive intervention strategies in this population. This study aims examine whether the magnesium depletion score (MDS) is CVD among individuals MASLD or metabolic alcohol (MetALD). A total 3802 participants MetALD were followed up over a median...

10.3390/nu17020244 article EN Nutrients 2025-01-10

Background: Detection of liver fibrosis helps to make therapeutic decisions and with screening in patients chronic diseases. Transient elastography (TE) is an accurate, noninvasive technique assess but sometimes it underestimated. Here we aimed for associations predictors related the underestimation using TE. Methods: We conducted a prospective cohort study involving adult cirrhosis who underwent TE had their clinical data analyzed. Patients were categorized into two groups based on...

10.3138/canlivj-2024-0038 article EN other-oa Canadian Liver Journal 2025-02-25

<title>Abstract</title> Background In the past three decades, incidence rate of cervical cancer has declined in high-income countries, but it remaines an important public health problem low - and middle-income with squamous cell carcinoma (CSCC) being main type. Patients advanced recurrence metastasis have a poor prognosis. Cervical exhibits extensive intra-tumoral phenotypic heterogeneity plasticity. Methods We analyzed single-cell RNA sequencing data available Comprehensive Gene Expression...

10.21203/rs.3.rs-6199573/v1 preprint EN cc-by Research Square (Research Square) 2025-03-27
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