A5041854739- Prenatal Screening and Diagnostics
- Protease and Inhibitor Mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Ethics and Legal Issues in Pediatric Healthcare
- Neonatal Respiratory Health Research
- Cystic Fibrosis Research Advances
- Pulmonary Hypertension Research and Treatments
- Neuroendocrine Tumor Research Advances
- Pharmaceutical studies and practices
- BRCA gene mutations in cancer
- Nutrition, Genetics, and Disease
- Child and Adolescent Health
- Congenital Anomalies and Fetal Surgery
- Genetic Syndromes and Imprinting
- Patient Dignity and Privacy
- Folate and B Vitamins Research
- Reproductive Health and Technologies
- Congenital Diaphragmatic Hernia Studies
- Pharmacological Effects and Toxicity Studies
- Asthma and respiratory diseases
- COVID-19 and Mental Health
- Peptidase Inhibition and Analysis
- Assisted Reproductive Technology and Twin Pregnancy
- Education, Leadership, and Health Research
- Neurofibromatosis and Schwannoma Cases
Lithuanian University of Health Sciences
2015-2025
Mykolas Romeris University
2015-2025
Vytautas Magnus University
2020-2024
Czech Academy of Sciences, Institute of Psychology
2021
Hospital of Lithuanian University of Health Sciences Kaunas Clinics
2011-2020
Vilnius University
2016
Lietuvos Bioetikos Komitetas
2015
University of Health Science
2012
Lund University
2007
Abstract Despite the critical role of culture in understanding adolescent self and identity, there is a lack cross‐culturally validated measures self‐construal. The present study evaluated cross‐national measurement invariance Aspects Identity Questionnaire‐IV (AIQ‐IV), assessing four dimensions self‐construal: personal, relational, public, collective. sample included 16,795 adolescents aged 14–19 years from 30 countries across continents. four‐factor structure AIQ‐IV obtained using...
Smoking is the main risk factor for development of chronic obstructive pulmonary disease (COPD) that has been recently defined as a systemic inflammatory disease. However, impact smoking itself on inflammation in COPD patients not yet well established. The aim our study was to investigate association between markers and status. We compared 202 current smokers, 61 ex-smokers 57 never-smokers, all patients. Assessments included medical history, spirometry, alpha-1 antitrypsin (AAT) genotyping,...
Multiple endocrine neoplasia type 1 (MEN 1) is a rare syndrome inherited in an autosomal dominant pattern, characterized by combinations of tumors the parathyroid glands, pituitary gland, and pancreatic islet cells more organs nonendocrine tissues. Germline mutations MEN1 gene are responsible for MEN syndrome, leading to inactive form menin protein. Benign lesions glands characteristic patients with syndrome; however, can develop carcinomas very rarely. This report presents clinical case...
Background and objectives: Reproductive disorders may occur not only due to environmental factors (air pollution, stressful lifestyle, previous abortions or the use of contraceptives) but also genetic factors. Materials Methods: The aim study was identify range frequency chromosomal aberrations in couples (n = 99) with infertility recurrent miscarriages Lithuania. data were collected from out-patient medical histories. divided into three groups based on pregnancy, childbirth number...
Hair loss can significantly impact an individual's psychological state, self-image, and lead to numerous personal, social, occupational problems. Although these impairments are well documented in primary studies reviews, the need for appropriate help is emphasized, there still a lack of knowledge broader specific picture. The patient's perspective vital while seeking understand content variables like "impaired body image" or "low self-esteem." This article advocates involving methodologies...
Recurrent miscarriage is a disease distinct from infertility, defined by three or more consecutive pregnancy losses. There are lot of causes which can be related with repetitive Miscarriages serious medical condition affects about 15-20% couples trying to get pregnant. Most them (about 50%) unknown and genetic factors compose 1-5% miscarriages. For this reason it important find out recurrent spontaneous abortions. In review we will analyze several cases including cytogenetic abnormalities...
Background and Objectives: Although multimorbidity poses many challenges for both individuals healthcare systems, information on how these patients assess the quality of their is lacking. This study assessed multimorbid patients' satisfaction with healthcare. Materials Methods: cross-sectional was a part project Joint Action-Chronic Diseases Promoting Healthy Ageing across Life Cycle its implementation. The included 400 arterial hypertension at least one concomitant chronic disease. Patients...
Abstract Objective The aim was to identify the critical levels of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and vascular endothelial growth factor-A in umbilical cord blood that could be used as markers for predicting central nervous system (CNS) damage retinopathy prematurity (ROP) preterm infants. Study Design A total 158 infants, born at 22 34 weeks gestation, were evaluated first week after birth 36 37 postconceptual age. Results significant relationship between CNS changes...
Background and objectives: Noninvasive prenatal testing (NIPT), which has been introduced clinically since 2011, uses the circulating cell-free fetal DNA in maternal blood to evaluate risk of a chromosomal anomaly. The aim this study was examine effectiveness NIPT using single nucleotide polymorphism method. Materials Methods: A retrospective conducted between 2013 2019. Natera Panorama test used analyze trisomies 21, 18, 13, X monosomy, trisomy, other sex chromosome abnormalities. positive...
IIn nt tr ro od du uc ct ti io on n: : Chronic obstructive pulmonary disease (COPD) has been recently defined as a systemic inflammatory disease, and congenital α1 antitrypsin deficiency is one of the well-established genetic risk factors for chronic disease.The aim our study was to evaluate possible associations with markers -CRP, sCD14, TNF-α, sTNFR-1, sTNFR-2 -in patients COPD different genotypes.M Ma at te er ri ia al l an nd d m me et th ho ds s: Serum biomarkers from (n = 355) COPD,...
Stargardt disease is a juvenile macular degeneration most often inherited in an autosomal recessive pattern, characterized by decreased vision the first 2 decades of life. This report presents clinical case disease: 10-year-old female patient complained blurry vision, and 4-year period, her visual acuity was reduced from OD=0.3 OS=0.3 to OD=0.08 OS=0.1, respectively. A genetic analysis revealed rare combination homozygous mutations ABCA4 gene, which caused disease. The presence different...
The recent introduction of cell-free DNA (cfDNA)-based noninvasive prenatal testing (NIPT) offers pregnant women a more accurate method than traditional serum screening methods for detecting fetal aneuploidies. Clinical trials have demonstrated the efficacy NIPT Down, Edwards and Patau syndromes. However approaches that take advantage single-nucelotide polymorphism (SNP) information potentially allow identification triploidy, chromosomal microdeletion syndromes other unusual genetic...
Homocysteine is an enzyme encoded by MTHFR (methylenetetrahydrofolate reductase) gene located on chromosome 1. Mutations in may result the afflicted metabolism of homocysteine and thus might increase risk recurrent miscarriages. In some cases, pregnancy loss could be prevented prescribing folic acid B group vitamin supplements. The demand sequencing for variations commonly overlooked doctors or genetic counsellors. To highlight this problem we present a case study miscarriages patient with...
Background and Objectives: The safety effectiveness of vaccines are among the key priorities in COVID-19 pandemic management. Moreover, evidence-based data regarding vaccine immunogenicity can play an important role building trust community vaccination. aim this study was to investigate Pfizer-BioNTech healthcare workers one hospital, 21 days after first dose. Materials Methods: This conducted Hospital Lithuanian University Health Sciences between February March 2021. employees who arrived...
Backround: Romantic relationships were described as the unique partnership where intimacy and mutual feelings of love affection are manifested. However they may be linked with some level anxiety depression - two separate conditions, that strongly to one another almost indistinguishable elements. The aim study analyse link between romantic & anxiety.
 Methods: A total 120 participants currently engaged in a dating relationship (80) marriage (40), specifically targeting young adults...