- Substance Abuse Treatment and Outcomes
- HIV, Drug Use, Sexual Risk
- Opioid Use Disorder Treatment
- Cannabis and Cannabinoid Research
- Homelessness and Social Issues
- Forensic Toxicology and Drug Analysis
- HIV/AIDS Research and Interventions
- Criminal Justice and Corrections Analysis
- Mental Health Treatment and Access
- Prenatal Substance Exposure Effects
- Hepatitis C virus research
- Alcohol Consumption and Health Effects
- Blood donation and transfusion practices
- Community Health and Development
- Neurotransmitter Receptor Influence on Behavior
- Schizophrenia research and treatment
- Health Policy Implementation Science
- Digital Mental Health Interventions
- Health disparities and outcomes
- Child and Adolescent Psychosocial and Emotional Development
- Hepatitis B Virus Studies
- Census and Population Estimation
- Liver Disease Diagnosis and Treatment
- Gambling Behavior and Treatments
- Mental Health and Patient Involvement
Burnet Institute
2015-2024
Monash University
2013-2024
Australian Institute of Family Studies
2019-2024
Government of Victoria
2024
Government of Western Australia Department of Health
2024
University of California, Los Angeles
2017-2020
Neurobehavioral Systems
2017
The Alfred Hospital
2017
UNSW Sydney
2009
The Open University
2006
We developed the FORCETM platform to overcome limitations of oligonucleotide delivery muscle and enable their applicability neuromuscular disorders. The consists an antigen-binding fragment, highly specific for human transferrin receptor 1 (TfR1), conjugated via a cleavable valine-citrulline linker. Myotonic dystrophy type (DM1) is disorder caused by expanded CUG triplets in DMPK RNA, which sequester splicing proteins nucleus, lead spliceopathy, drive disease progression. Multiple surrogate...
We tested whether patrons of the night-time economy who had co-consumed energy drinks or illicit stimulants with alcohol higher blood concentration (BAC) levels than consumed only alcohol.Street intercept surveys (n = 4227) were undertaken between 9 p.m. and 5 a.m. over a period 7 months.Interviews walking through entertainment precincts, queuing to enter venues exiting in five Australian cities.The response rate was 92.1%; more half study sample male (60.2%) median age 23 years (range...
Abstract Introduction and Aims There is little research describing how intoxication levels change throughout the night in entertainment districts. This aims to describe of alcohol across multiple A ustralian metropolitan regional nightlife Design Methods study was conducted night‐time districts three cities ( S ydney, M elbourne P erth) two W ollongong G eelong) ustralia. Data collection occurred approximately fortnightly each city on a F riday or aturday between 8 pm 5 am . Brief structured...
Anxiety and depression are the most common mental health disorders experienced by Australians. These commonly found in people who use methamphetamine; however, much of this research has involved participants recruited from treatment settings inject methamphetamine. We therefore explored (1) prevalence moderate to severe anxiety a community-recruited cohort smoked methamphetamine (2) examined potential factors associated with or cohort.Data were derived baseline surveys 725 prospective 'VMAX'...
Methamphetamine dependence is a significant global health concern for which there are no approved medications. The cysteine prodrug, N-acetylcysteine (NAC), has been found to ameliorate glutamate dysregulation in addiction, and reduce craving methamphetamine other drugs. We evaluated the efficacy safety of NAC as pharmacotherapy dependence.
Mental health disorders are ranked globally as the single largest contributor to non-fatal ill-health. Social support can be a means of reducing and managing depression. However, depression also impact on person's level social support.As men typically have fewer sources than females, this study investigated bi-directional associations between depressive symptoms perceived levels among Australian males, aged 18-63.Three waves panel data from Ten Men: The Longitudinal Study Male Health...
Methamphetamine use is associated with numerous harms and consequently represents a significant impact on Australia's treatment health service sectors. This article presents baseline findings from the first cohort study of regular methamphetamine users conducted in Melbourne, describing associations between participant characteristics behaviours dependence. A total 255 Melbourne-based, were recruited during 2010 administered structured questionnaire. Most male Australian-born median age 30...
Abstract Background and Aims High rates of loss to follow‐up represent a significant challenge clinical trials pharmacological treatments for methamphetamine (MA) use disorder. We aimed estimate test the relationship between achieving maintaining abstinence in initial weeks study participation subsequent retention such trials, hypothesizing that participants able achieve early would be less likely drop out. Design Data from four randomized controlled (RCTs) MA disorder were pooled analyzed...
Abstract Background and Aims Few studies of the impacts coronavirus disease 2019 (COVID‐19) public health measures on drug markets use patterns have used longitudinal data. We aimed to examine whether COVID‐19 were associated with increases in methamphetamine price, decreases frequency subsequent changes secondary outcomes other metropolitan Melbourne regional Victoria. Design Longitudinal analysis framework was from a cohort people who methamphetamine. Setting Victoria state, Australia....
Abstract Introduction and Aims Past research investigating syndemic factors HIV‐related outcomes has overlooked the impact of structural conditions on behaviours linked with HIV transmission disease progression. Given prevalent substance use among our sample, we explored whether four indicative social marginalisation previously correlated increased risk for infection demonstrated (additive/synergistic) effects on: (i) viral suppression; (ii) self‐reported involvement in sexual a prospective...
Limited research has investigated methamphetamine use and related harms in rural regional Australia. We whether people who used non-metropolitan Victoria differed their sociodemographics were more likely to be methamphetamine-dependent than those recruited Melbourne.
Abstract Changes in the working, study and social lives of emerging adults due to COVID‐19 pandemic have led greater need for external supports. Many who lived independently may sought that support by returning live with parents. This identifies factors associated returns made between 2019 2020. It describes supports needed obtained, relationships parents their resident correlates poor coping high psychological distress. Data from Longitudinal Surveys Australian Youth Study Children were...
<i>Aims:</i>This paper examines the epidemiology of ecstasy use and harm in Australia using multiple data sources. <i>Design:</i> The included (1) Australian Customs Service 3,4-methylenedioxymethamphetamine (MDMA) detections; (2) National Drug Strategy Household Secondary Student Alcohol Surveys; (3) from Australia’s Related Drugs Reporting System; (4) number recorded police incidents for possession distribution collated by N.S.W. Bureau Crime Statistics Research;...