A5101112378- Gas Sensing Nanomaterials and Sensors
- Metal-Organic Frameworks: Synthesis and Applications
- Covalent Organic Framework Applications
- Analytical Chemistry and Sensors
- Immune Cell Function and Interaction
- Nanomaterials for catalytic reactions
- Catalytic Processes in Materials Science
- Conducting polymers and applications
- Advanced Sensor and Energy Harvesting Materials
- T-cell and B-cell Immunology
- Organic Electronics and Photovoltaics
- Advanced Chemical Sensor Technologies
- Advanced Photocatalysis Techniques
- Advanced biosensing and bioanalysis techniques
- Ammonia Synthesis and Nitrogen Reduction
- Ferroelectric and Negative Capacitance Devices
- Adipokines, Inflammation, and Metabolic Diseases
- Oxidative Organic Chemistry Reactions
- Ion Transport and Channel Regulation
- Mesoporous Materials and Catalysis
- SARS-CoV-2 and COVID-19 Research
- Tissue Engineering and Regenerative Medicine
- Asymmetric Hydrogenation and Catalysis
- Organic Light-Emitting Diodes Research
- Advanced Memory and Neural Computing
Zhejiang Pharmaceutical College
2025
Harvard University
2021-2024
Southern Medical University
2024
Affiliated Hospital of North Sichuan Medical College
2022-2024
Boston VA Research Institute
2021-2024
Shanghai Sixth People's Hospital
2024
Shanghai Jiao Tong University
2024
Xian Central Hospital
2024
Shanghai University
2024
Changchun University of Technology
2019-2023
Abstract Carbon materials, including graphite, hard carbon, soft graphene, and carbon nanotubes, are widely used as high‐performance negative electrodes for sodium‐ion potassium‐ion batteries (SIBs PIBs). Compared with other materials abundant, low‐cost, environmentally friendly, have excellent electrochemical properties, which make them especially suitable electrode of SIBs PIBs. traditional modifications the morphology size nanomaterials represent effective strategies to improve quality...
Neuroimmune cross-talk participates in intestinal tissue homeostasis and host defense. However, the matrix of interactions between arrays molecularly defined neuron subsets immunocyte lineages remains unclear. We used a chemogenetic approach to activate eight distinct neuronal subsets, assessing effects by deep immunophenotyping, microbiome profiling, transcriptomics organs. Distinct immune perturbations followed activation: Nitrergic neurons regulated T helper 17 (T
Dysbiosis in the gut microbiota affects several systemic diseases, possibly by driving migration of perturbed intestinal immunocytes to extraintestinal tissues. Combining Kaede photoconvertible mice and single-cell genomics, we generated a detailed map migratory trajectories from colon, at baseline, models inflammation. All lineages emigrated colon an S1P-dependent manner. B lymphocytes represented largest contingent, with unexpected circulation nonexperienced follicular cells, which carried...
Abstract Fabrication of non‐noble metal‐based heterogeneous catalysts by a facile and cost‐effective strategy for ecofriendly catalytic transfer hydrogenation (CTH) is great significance organic transformations. A cobalt@nitrogen‐doped carbon (Co@NC) catalyst was prepared from renewable biomass‐derived sucrose, harmless melamine, earth‐abundant Co(AcO) 2 as the precursor materials hydrothermal treatment carbonization. Co nanoparticles (NPs) were coated with NC shells uniformly embedded in...
Metal-nanocluster-doped porous materials are attracting considerable research attention due to their specific catalytic performance. In this study, core–shell metal–organic frameworks@covalent organic polymer (MOF@COP) nanocomposites were formed by the covalent linking of chemically stable COP on surface size-selective UiO-66-NH2. Pd nanoclusters with an average diameter ∼0.8 nm successfully confined in UiO-66-NH2@COP, and obtained nanoreactor, referred as UiO-66-NH2@COP@Pd, exhibited...
Follicular helper T (Tfh) cells are essential for germinal center formation and effective humoral immunity, which undergo different stages of development to become fully polarized. However, the detailed mechanisms their regulation remain unsolved. Here we found that E3 ubiquitin ligase VHL was required Tfh cell function upon acute virus infection or antigen immunization. acted through hypoxia-inducible factor 1α (HIF-1α)-dependent glycolysis pathway positively regulate early initiation. The...
Heteroatom-doped carbon materials (HDCMs) with abundant active functional groups and stable structural characteristics are promising catalysts for eco-friendly metal-free catalysis.
Iron overload is closely associated with metabolic dysfunction. However, the role of iron in hypothalamus remains unclear. Here, we find that hypothalamic levels are increased, particularly agouti-related peptide (AgRP)-expressing neurons high-fat-diet-fed mice. Using pharmacological or genetic approaches, reduce AgRP by central deferoxamine administration transferrin receptor 1 (Tfrc) deletion, ameliorating diet-induced obesity and related Conversely, Tfrc-mediated leads to overeating...
A stable Pd@TP-POP catalyst with highly dispersed ultrafine Pd NPs confined in its organic pores was fabricated for catalytic reduction of 4-nitrophenol and transfer hydrogenation aromatic aldehydes under very mild conditions.
Polymer-derived N,S co-doped carbon materials (PDNSC-X) with a hierarchically porous structure were facilely prepared by cost-effective and convenient strategy subsequently used as efficient metal-free catalysts.
Colorectal cancer is one of the most common cancers, and its incidence rate keeps increasing worldwide. Epidermal growth factor receptor (EGFR) highly expressed in colorectal cells, activation leads to downstream kinase pathways promote cell growth, resulting tumour progression. EGFR only small amounts normal however, it overexpressed cells a potential marker, thus detection which great importance. This work proposes novel sensitive electrochemical immunosensor based on nucleic acid aptamer...
Fibrocytes are collagen-producing leukocytes that accumulate in patients with systemic sclerosis (SSc; scleroderma)-related interstitial lung disease (ILD) via unknown mechanisms have been associated altered expression of neuroimmune proteins. The extracellular matrix (ECM) influences cellular phenotypes. However, a relationship between the ECM and fibrocytes SSc has not explored. aim this study was to use novel translational platform based on decellularized human lungs determine whether...
Infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) provokes a potentially fatal pneumonia with multiorgan failure, and high systemic inflammation. To gain mechanistic insight ferret out the root of this immune dysregulation, we modeled, in vitro coculture, interactions between infected epithelial cells immunocytes. A strong response was induced monocytes B cells, SARS-CoV-2-specific inflammatory gene cluster distinct from that seen influenza or Ebola virus-infected...