Saijun Zhou

ORCID: 0000-0002-3004-9871
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Research Areas
  • Arsenic contamination and mitigation
  • Heavy metals in environment
  • Cancer-related molecular mechanisms research
  • Diabetes Treatment and Management
  • Metal Extraction and Bioleaching
  • Acute Ischemic Stroke Management
  • Chronic Kidney Disease and Diabetes
  • RNA modifications and cancer
  • S100 Proteins and Annexins
  • Water Quality Monitoring and Analysis
  • Advanced Glycation End Products research
  • Pancreatic function and diabetes
  • Liver Disease Diagnosis and Treatment
  • Lipoproteins and Cardiovascular Health
  • Adsorption and biosorption for pollutant removal
  • Retinal Diseases and Treatments
  • Minerals Flotation and Separation Techniques
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Circadian rhythm and melatonin
  • Immune Response and Inflammation
  • Cerebrovascular and Carotid Artery Diseases
  • Atherosclerosis and Cardiovascular Diseases
  • MicroRNA in disease regulation
  • Heavy Metal Exposure and Toxicity
  • Water Quality Monitoring Technologies

Hunan University of Science and Technology
2011-2025

Tianjin Medical University
2014-2024

Wenzhou Medical University
2015-2024

First Affiliated Hospital of Wenzhou Medical University
2015-2024

Yunnan University
2024

Institute of Endocrinology
2022-2023

National Health and Family Planning Commission
2022

Shijiazhuang University
2019

PLA Army Engineering University
2019

Wuhan University of Technology
2015-2018

Accumulating evidence has implicated that liraglutide, one of the human glucagon‑like peptide‑1 (GLP‑1) analogues, elicits protective effects on diabetic nephropathy; however, mechanism yet to be fully elucidated. The present study aimed assess effect and underlying mechanisms liraglutide in nephropathy. Wistar rats with streptozotocin‑induced diabetes mellitus were subcutaneously injected or phosphate buffer for 12 weeks at a dose 0.3 mg/kg/12 h. biochemical parameters determined, renal...

10.3892/mmr.2014.2555 article EN Molecular Medicine Reports 2014-09-10

To explore the efficacy of S100 calcium-binding protein B (S100β) in differentiating between intracerebral hemorrhage (ICH) and ischemic stroke (IS).From June 2014 to July 2015, 46 ICH 71 IS patients who had undergone computed tomography (CT) scans were enrolled. Patients' neurological deficits evaluated by National Institutes Health scale (NIHSS), modified Rankin (mRS) was used assess functional disability 90 days after discharge. Plasma S100β measured from a blood sample drawn upon arrival...

10.1080/01616412.2016.1152675 article EN Neurological Research 2016-03-24

Background and Purpose— We aimed to develop validate a grading scale for predicting 30-day mortality 90-day functional outcome in patients with primary pontine hemorrhage (PPH). Methods— retrospectively reviewed records of consecutive first-ever from 3 teaching hospitals between 2005 2012. Independent factors associated were identified by logistic regression establish risk stratification scale, named the new PPH score. For validation score, we prospectively recruited subjects 10 units...

10.1161/strokeaha.116.015326 article EN Stroke 2016-12-09

Antimony oxidizing bacteria (SbOB) and iron oxides are the main driving factors to weathering dissolution oxidation of stibnite (Sb2S3) waste ore. The characteristics process in absence strain AO-1 oxides, Pseudomonas sp. AO-1-mediated (AO-1-mediated), Fe (Fe, Fe2(SO4)3, FeS2) -mediated, coupled-mediated groups (Fe+AO-1, Fe2(SO4)3+AO-1, FeS2+AO-1) under various pH values were examined through sequential batch experiments. results showed that all AO-1-mediated, Fe-mediated can promote...

10.1016/j.eti.2024.103640 article EN cc-by Environmental Technology & Innovation 2024-04-16

Heavy metal pollution in soils caused by mining and smelting has attracted worldwide attention for its potential health risks to residents. This paper studies the concentrations accumulations of Sb As both vegetables human from Xikuangshan (XKS) mine, Hunan, China. Results showed that were severely polluted As; have significant positive correlation. quite different: Coriandrum sativum L. was highest Sb, Allium fistulosum As, Brassica pekinensis lowest Daucus carota advantage accumulating had...

10.1155/2015/909724 article EN cc-by Journal of Analytical Methods in Chemistry 2015-01-01

Antimony ore tailings slag was used analyze heavy metals, chemical speciation, and leaching characteristics.The results show that the residual silicate phases account for 65.44% of Sb, 77.22% As, 87.94% Hg, 58.53% Pb, 71.27% Cd, 96.34% Zn.Although exchangeable carbonate 7.71% 0.71% 3.77% 4.82% 1.83% 1.73% Zn, water-or-acid-soluble contribute more to speciation metals.Concentrations Hg in leachates increased with increasing solid-liquid ratio, decreasing particle size temperature.In simulated...

10.15244/pjoes/85006 article EN Polish Journal of Environmental Studies 2018-08-01

Major sources of pollution during the antimony (Sb) mining and processing are waste rock, smelting waste, tailings dam, underground tunnel wastewater. The aim present study was to assess magnitude from Sb mine by taking four types samples: soil in rock zone, wastewater zone. Sixty samples zones were taken for experimental work, contents morphological characteristics six potentially toxic elements (PTEs) such as Sb, As, Hg, Pb, Cd, Zn measured using a hydride generation atomic fluorescence...

10.1155/2019/2754385 article EN cc-by Journal of Analytical Methods in Chemistry 2019-09-08

The cardioprotective effects of sodium-glucose cotransporter type 2 (SGLT2) inhibitors have been demonstrated in many studies. However, their benefits for end-stage kidney disease patients, particularly those on peritoneal dialysis, remain unclear. SGLT2 inhibition has shown protective some studies, but the mechanisms are still unknown. Herein, we investigated Canagliflozin vitro by simulating hypoxia with CoCl human mesothelial cells (HPMCs) and rats intraperitoneal injection 4.25%...

10.3389/fphar.2023.1152611 article EN cc-by Frontiers in Pharmacology 2023-05-11

In this study, a renewable and reusable immobilized Microcystis aeruginosa microsphere loaded with magnetic Nano-Fe3O4 composite adsorbent material is designed to study the treatment of wastewater containing heavy metal Sb(III). Through static absorption experiments combined various characterization methods, article studies process mechanism Sb(III), investigates optimal preparation conditions environmental influencing factors. The results show that for microspheres materials are 50.0% mass...

10.3390/w16050681 article EN Water 2024-02-26

Background Diabetes mellitus (DM) is linked to an increased risk of lung cancer; however, the exact molecular basis unclear. Methods We used a microarray method and found group microRNAs differently expressed in cancer cells at high or low glucose treatment. Results Among these, miR‐194 changed significantly, which indicated further analysis. was significantly downregulated non‐small cell (NSCLC) cultured (HG) medium clinical NSCLC tissues with DM. The introduction suppressed proliferation,...

10.1111/1759-7714.13038 article EN cc-by-nc Thoracic Cancer 2019-03-21

The aim of this study was to investigate the effect C-reactive protein/oxidised low-density lipoprotein/β2-glycoprotein I (CRP/oxLDL/β2GPI) complex on atherosclerosis (AS) in diabetic BALB/c mice.BALB/c mice were fed high-fat and normal diet. Eight weeks later, with diet injected streptozotocin (STZ) induce diabetes. respectively twice monthly 20 μg oxLDL, β2GPI, 40 oxLDL/β2GPI complex, 44 CRP/oxLDL/β2GPI PBS. Aortas stained Sudan IV lipid plaque formation. infiltration condition smooth...

10.1186/1476-511x-12-42 article EN cc-by Lipids in Health and Disease 2013-03-26

Background: Early and accurate prediction of outcome in acute stroke is important. The aim this prospective study was to explore the correlation between serum triiodothyronine level prognosis ischemic patients. Methods: A observational which included 359 consecutive patients with from December 2014 November 2015 interrogated. Serum (T3) concentrations were measured on admission understand their value predicting functional within 90 d using multivariable models adjusted for confounding...

10.1080/00207454.2016.1211649 article EN International Journal of Neuroscience 2016-07-12

We evaluated the direct release to environment of a number potentially toxic elements (PTEs) from various processing nodes at Xikuangshan Antimony Mine in Hunan Province, China. Sampling wastewater, dust, and solid waste characterizing PTE content (major Sb, As, Zn, associated Hg, Pb, Cd) activities, we extrapolated findings assess wider environmental significance using pollution index potential ecological risk index. The Zn wastewater antimony benefication industry group PTEs fine ore bin...

10.3390/pr8010029 article EN Processes 2019-12-25
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