A5066272149- melanin and skin pigmentation
- Acne and Rosacea Treatments and Effects
- Skin Protection and Aging
- Dermatologic Treatments and Research
- Psoriasis: Treatment and Pathogenesis
- Dermatology and Skin Diseases
- Dermatological and COVID-19 studies
- Allergic Rhinitis and Sensitization
- Autoimmune Bullous Skin Diseases
- Herpesvirus Infections and Treatments
- Diversity and Career in Medicine
- Cutaneous lymphoproliferative disorders research
- Infection Control and Ventilation
- Health Systems, Economic Evaluations, Quality of Life
- Nail Diseases and Treatments
- Parvovirus B19 Infection Studies
- Cutaneous Melanoma Detection and Management
- Atherosclerosis and Cardiovascular Diseases
- Pharmaceutical studies and practices
- Mast cells and histamine
- Asthma and respiratory diseases
- Medicine and Dermatology Studies History
- Food Allergy and Anaphylaxis Research
- T-cell and Retrovirus Studies
- Poxvirus research and outbreaks
The University of Texas Southwestern Medical Center
2015-2025
Plano Cancer Institute
2020-2024
Institute of Applied Dermatology
2024
Dermatology Treatment & Research Center
2023-2024
Tulane University
2024
University of California, Davis
2023
University of South Florida
2023
Sol-Gel Technologies (Israel)
2023
Moffitt Cancer Center
2023
Southwestern Medical Center
2015-2021
Cutaneous reactions after messenger RNA (mRNA)-based COVID-19 vaccines have been reported but are not well characterized.
BackgroundCoronavirus disease 2019 (COVID-19) has associated cutaneous manifestations.ObjectiveTo characterize the diversity of manifestations COVID-19 and facilitate understanding underlying pathophysiology.MethodsCase series from an international registry American Academy Dermatology International League Dermatological Societies.ResultsThe collected 716 cases new-onset dermatologic symptoms in patients with confirmed/suspected COVID-19. Of 171 laboratory-confirmed COVID-19, most common...
Cutaneous reactions after COVID-19 vaccination have been commonly reported; however, histopathologic features and clinical correlations not well characterized.We evaluated for a history of skin biopsy all reports associated with identified in an international registry. When histopathology were available, we categorized them by reaction patterns.Of 803 vaccine reported, 58 (7%) cases had available review. The most common pattern was spongiotic dermatitis, which clinically ranged from robust...
Vitiligo is a chronic autoimmune disease that causes skin depigmentation. A cream formulation of ruxolitinib (an inhibitor Janus kinase 1 and 2) resulted in repigmentation phase 2 trial involving adults with vitiligo.We conducted two 3, double-blind, vehicle-controlled trials (Topical Ruxolitinib Evaluation Study [TRuE-V1] [TRuE-V2]) North America Europe involved patients 12 years age or older who had nonsegmental vitiligo depigmentation covering 10% less total body-surface area. Patients...
Since the start of COVID-19 pandemic, multiple studies have reported that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with dermatological manifestations.1Freeman EE McMahon DE Lipoff JB et al.The spectrum COVID-19-associated dermatologic manifestations: an international registry 716 patients from 31 countries.J Am Acad Dermatol. 2020; 83: 1118-1129Summary Full Text PDF PubMed Scopus (269) Google Scholar However, data on duration signs and symptoms for myriad...
Evidence-based recommendations for the treatment of vitiligo in pediatric, adolescent, and young adult patients US are needed.
Abstract Background Acne‐induced hyperpigmentation (AIH) may accompany acne vulgaris (AV) inflammation in all skin phototypes. Trifarotene has shown depigmenting properties vivo. This study evaluated trifarotene plus skincare because it is increasingly recognized that holistic AV management should include and treatments. Methods a phase IV double‐blind, parallel‐group of patients (13–35 years) with moderate AIH treated ( N = 60) or vehicle 63) regimen (moisturizer, cleanser, sunscreen) for...
Background: Modified Kligman's formula (mKF) is the gold standard treatment for melasma; however, its prolonged use not recommended due to side effects. Cysteamine a potent, safe, and effective depigmenting agent. Here, we conducted double-blind, randomized, placebo-controlled clinical trial assess efficacy of cysteamine isobionic-amide -- complex with enhanced compared it mKF melasma.
Skin hyperpigmentation, including melasma, solar lentigines, and post-inflammatory results in a significant impact on patient quality of life. Unfortunately, to date, many over-the-counter (OTC) options have often been limited by efficacy, safety tolerability concerns. Additionally, education disease manifestation root causes hyperpigmentation leaves patients undiagnosed untreated. Melanogenesis is driven complex pathway resulting the ultimate production deposition melanin skin. The major...
Atopic dermatitis is highly prevalent in black/African American, Asian, and Hispanic patients, making assessment of these populations clinical trials important. Crisaborole ointment, 2%, a nonsteroidal phosphodiesterase 4 inhibitor for the treatment mild-to-moderate atopic dermatitis. In two pivotal phase III patients aged ≥ 2 years, crisaborole was superior to vehicle reducing global disease severity. The most common treatment-related adverse event application site pain. objective this...