A5015983451- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Parasites and Host Interactions
- Synthesis and Biological Evaluation
- Liver Disease Diagnosis and Treatment
- Dialysis and Renal Disease Management
- Advanced Glycation End Products research
- Physical Education and Gymnastics
- Nutrition and Health in Aging
- Health, Nursing, Elderly Care
- Nutritional Studies and Diet
- Tryptophan and brain disorders
- Gout, Hyperuricemia, Uric Acid
- Antioxidant Activity and Oxidative Stress
- Tea Polyphenols and Effects
- Adipose Tissue and Metabolism
- Health Education and Validation
- Laser Applications in Dentistry and Medicine
- Vitamin K Research Studies
- Public Health in Brazil
- Coccidia and coccidiosis research
- Herpesvirus Infections and Treatments
- Muscle and Compartmental Disorders
- Wildlife Conservation and Criminology Analyses
- Diabetes, Cardiovascular Risks, and Lipoproteins
University of Georgia
2025
Universidade Federal dos Vales do Jequitinhonha e Mucuri
2015-2023
Universidade Federal de Viçosa
2013-2017
Although curcumin can increase the effectiveness of drugs against malaria, combination therapies using molecule have never been investigated in Chagas disease (ChD). Therefore, we evaluated efficacy as a complementary strategy to benznidazole (Bz)-based chemotherapy mice acutely infected with Trypanosoma cruzi Eighty-four 12-week-old Swiss were equally randomized into seven groups: uninfected (NI), T. and untreated (INF), treated 100 mg/kg body weight Bz (B100), 50 (B50), (C100), plus (B100...
The influence of diet on metabolic syndrome and oxidative stress are not completely known. This cross-sectional study assessed the association red meat white consumption with syndrome, insulin resistance lipid peroxidation in Brazilian middle-aged men. A total 296 subjects (age: 50.5 ± 5.0 years, body mass index: 25.8 3.5 kg/m2) were evaluated. Anthropometry, lifestyle features, blood biochemical parameters, diagnosis homeostatic model assessment for resistance, a marker (oxidized...
Summary A 16‐year‐old Warmblood gelding had historically been evaluated for a chronic right forelimb lameness, localised with palmar digital nerve block. The lameness was recurrent despite medication of the fore distal interphalangeal joint. Magnetic resonance imaging (MRI) showed proliferative intermediate‐to‐low signal tissue in location dorsal recess joint, an overlying defect common extensor tendon. Given persistent over following 24 months, no improvement to neurectomy performed. Three...
The present cross-sectional study assessed the potential relationships of carotenoid intake with lipid and oxidative stress markers in middle-aged men. A total 296 apparently healthy men (mean age 50·5 ( sd 5·0) years, BMI 25·8 3·5) kg/m 2 ) were recruited to participate study. Dietary intake, anthropometry, blood pressure, lifestyle features, urine biomarkers using validated procedures. included NEFA, Castelli index, TAG:HDL ratio; urinary 8-hydroxy-2′-deoxyguanosine (8-OHdG), 8-iso-PGF2α...
Although suramin (Sur) is suggested as a potential drug candidate in the management of Chagas disease, this issue has not been objectively tested. In study, we examined applicability concomitant treatment with benznidazole (Bz) and mice infected virulent strain Trypanosoma cruzi. Eighty 12-week-old male C57BL/6 were equally randomized eight groups: (i) noninfected (negative control) T. cruzi Y receiving (ii) no (positive control), (iii) Bz, 100 mg/kg body weight per day, (iv) Sur, 20...
Summary This study investigated the pathological morphofunctional adaptations related to imbalance of exercise tolerance triggered by paraquat ( PQ ) exposure in rats. The rats were randomized into four groups with eight animals each: (a) SAL (control): 0.5 ml 0.9% NaCl solution; (b) 10: 10 mg/kg; (c) 20: 20 and (d) 30: 30 mg/kg. Each group received a single injection . After 72 hours, subjected an incremental aerobic running test until fatigue order determine tolerance, blood glucose...
Summary This study investigates the influence of gallium–arsenide (GaAs) laser photobiostimulation applied with different energy densities on skin wound healing by secondary intention in rats. Three circular wounds, 10 mm diameter, were made dorsolateral region 21 Wistar rats weighting 282.12 ± 36.08 g. The animals equally randomized into three groups: Group SAL , saline solution 0.9%; L3, GaAs 3 J/cm 2 ; L30, 30 . Analyses cells, blood vessels, collagen and elastic fibres,...
We investigated the effects of E. edulis bioproducts (lyophilized pulp [LEE], defatted lyophilized [LDEE], and oil [EO]) on nonalcoholic fatty liver disease (NAFLD) induced by a high‐fat diet (HFD) in rats. All products were chemically analyzed. In vivo , 42 rats equally randomized into seven groups receiving standard diet, HFD alone or combined with EO, LEE, LDEE. After NAFLD induction, LDEE, EO was added to animals’ for 4 weeks. LEE rich polyunsaturated acids. From degreasing, LDEE...
Abstract Objectives This study investigated the combined effects of benznidazole (BZ) and ibuprofen (IB) on oxidative inflammatory status cardiac tissue in vivo. Methods Swiss mice were randomized groups receiving BZ (100 mg/kg) IB (400 alone or (BZ + 200 400 mg/kg). Control animals concurrently treated with 1% carboxymethyl cellulose. All treatments administered orally for 7 days. Key findings treatment increased production nitrogen/oxygen-reactive species, malondialdeyde, carbonyl...
Introdução: A autoavaliação do estado de saúde pode ser considerada um preditor significante e independente funcionalidade morbimortalidade em idosos. Objetivo: Verificar a associação indicadores sociodemográficos, com negativa da (AANS) Métodos: Estudo transversal, uma amostra estratificada idosos comunitários município Diamantina (MG), Brasil. Para avaliar AANS as variáveis sociodemográficas, foi utilizado o Questionário BOAS – Brazil Old Age Schedule. Os testes Timed up & go...
The aims of this cross-sectional study were to explore the ability serum interleukin 18 (IL-18) and adiponectin identify metabolic syndrome (MetS), verify their association with an index central lipid overaccumulation (lipid accumulation product (LAP)) cardiometabolic risk factors in a population middle-aged Brazilian men. A group 218 apparently healthy men (age, 50.3 ± 4.97 years) underwent anthropometric, clinical, sociodemographic, standard biochemical assessments. LAP was calculated...
Hyperuricemia is related to Metabolic Syndrome (MetS) and cardiovascular diseases, but the use of serum uric acid (UA) diagnose MetS currently ignored in clinical practices.To examine impact UA on diagnostic relationship with cardiometabolic risk factors apparently healthy Brazilian middle-aged men residents a city Minas Gerais.In cross-sectional analysis, 289 underwent anthropometric, clinical, sociodemographic blood biochemical evaluation. By using receive operating curve internal cutoff...
O plasma rico em plaquetas (PRP) é um produto derivado da centrifugação do sangue total, sendo fatores bioativos, como os de crescimento. Apesar ampla utilização processos cicatriciais, há controvérsia sobre a eficácia terapia na cicatrização cutânea. objetivo desse estudo foi quantificar e comparar concentração dos TGF-β1 PDGF-BB no PRP, sanguíneo pele, durante diferentes fases processo pele tratada ou não com PRP. Foram utilizados sete equinos machos castrados, mestiços, hígidos, idade...
This study investigated the relationship between enteroendocrine and mucus-secreting cells distribution, severity of colonic mucosal injury intestinal motility in experimental colorectal carcinogenesis. Using a standardized murine model carcinogenesis, eight-weeks-old female Wistar rats weighting 147.30 ± 29.15g were randomized into two groups receiving subcutaneous injection 0.9% saline (control) or chemical carcinogen 1,2-dimethylhydrazine (DMH) at 20 mg/kg per week during 10 weeks....
The pathogens Schistosoma mansoni and Paracoccidioides brasiliensis share common geographic areas, determining infectious diseases with high mortality rates worldwide . Histopathological immunological changes induced by each pathogen are well understood; however, the host responses to S. P. coinfection still unknown. Thus, we investigated liver damage cytokines production in a murine model acutely chronically coinfected these pathogens. Fourty male Swiss mice were infected alone or...