A5090405796- Epigenetics and DNA Methylation
- Birth, Development, and Health
- Autism Spectrum Disorder Research
- Maternal Mental Health During Pregnancy and Postpartum
- Nerve injury and regeneration
- Cannabis and Cannabinoid Research
- Nutrition, Genetics, and Disease
- Intergenerational Family Dynamics and Caregiving
- Childhood Cancer Survivors' Quality of Life
- Child Development and Digital Technology
- Family Support in Illness
Universidade Federal do Espírito Santo
2021-2024
The aim of this study was to investigate socioeconomic stressors predictive depressive symptoms and possible epigenetic changes in the glucocorticoid receptor – NR3C1-1F an encoding gene involved symptoms. A total 321 adult volunteers from southeastern Brazil were recruited evaluate symptoms, socio-demographic economic factors, including food nutritional security (FNS) or insecurity (FNiS) status, region methylation by pyrosequencing. Depressive symptom determinants investigated using a...
Brain-derived neurotrophic factor (BDNF) gene regulation plays an important role in long-term memory formation, and the DNA methylation (DNAm) level of BDNF promoters has been associated with episodic deficits. Our aim was to explore association between DNAm levels promoter IV verbal learning performance healthy women. We conducted a cross-sectional study by recruiting 53 individuals. Episodic assessed using Rey Auditory Verbal Learning Test (RAVLT). Clinical interviews, RAVLT, blood sample...
Background Dietary composition can modify gene expression, favoring the development of chronic diseases via epigenetic mechanisms. Objective Our study aimed to investigate relationship between dietary patterns and NR3C1 methylation in users Brazilian Public Unified Health System (SUS). Methods We recruited 250 adult volunteers evaluated their socioeconomic status, psychosocial characteristics, lifestyle, anthropometrics. Peripheral blood was collected for cortisol levels, glycemia, lipid...