A5062323958- Toxin Mechanisms and Immunotoxins
- Mesenchymal stem cell research
- Plant tissue culture and regeneration
- Transgenic Plants and Applications
- Tissue Engineering and Regenerative Medicine
- Reproductive Biology and Fertility
- Wound Healing and Treatments
- Virus-based gene therapy research
- Phytochemistry Medicinal Plant Applications
- Periodontal Regeneration and Treatments
- Extracellular vesicles in disease
- Bariatric Surgery and Outcomes
- Corneal Surgery and Treatments
- Cancer Diagnosis and Treatment
- Veterinary Orthopedics and Neurology
- Synthesis of Organic Compounds
- Plant Toxicity and Pharmacological Properties
- Dermatology and Skin Diseases
- Helminth infection and control
- Urologic and reproductive health conditions
- Autopsy Techniques and Outcomes
- RNA Interference and Gene Delivery
- Animal testing and alternatives
- Environmental and biological studies
- Animal Genetics and Reproduction
Universidade Católica de Brasília
2019-2023
Universidade Federal de Minas Gerais
2000
The One Conservation is an integrative process for biodiversity conservation. This communication describes how this integrated method, involving many institutions, resulted in the birth of a jaguar cub that should be reintroduced to wild, thereby contributing species' long-term survival. Each parent was saved from wilderness. While sire as cub, dam rescued after devastating Pantanal wildfires killed over 16.9 million vertebrates. Rescues, treatments, and ex situ care involved large number...
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To evaluate the use of mesenchymal stem cells (MSCs) in attenuation canine atopic dermatitis (AD).Sixteen dogs were selected and divided into three groups, mild, moderate, severe, according to Canine Atopic Dermatitis Extent Severity Index (CADESI-4). They evaluated for 82 days. The protocol recommended this experiment was inject 2 × 106/kg bodyweight MSC's all groups by intravenous route with intervals applications 21 degree pruritus examining visual analog scale, CADESI-4, histopathology...
Abstract Valuable female cattle are continuously subject to follicular puncture (ovum pick-up - OPU). This technique is commonly used for in-vitro embryo production, but may result in ovarian lesion. Mesenchymal stem cells (MSC) ameliorate the function of injured tissues, their use treat lesions has not been established. We investigated whether a local injection MSC would reduce negative effects repeated OPU under acute and chronic scenarios bovines. First, we performed four sessions...
The cranial cruciate ligament rupture (CCLR) is the most commonly encountered orthopedic condition in dogs. Among various techniques to treat this condition, tibial tuberosity advancement (TTA) has been used obtain rapid recovery of affected knee. objective study was evaluate viability use mesenchymal stem cells (MSC) implanted osteotomy site obtained by TTA nine dogs diagnosed with CCLR. MSC were isolated from adipose tissue and cultured for eight days, animals divided into two groups....
Objectives: This study is aimed to evaluate the cytotoxic action of two homoeopathic medicines that are derived from Viscum album (VA) extract. Materials and Methods: An osteosarcoma cell line was cultured in presence VA preparations (VAD3 VAD30) viability evaluated using MTT assay. The U-2 OS plated 96-well plates for 24 h with culture medium at 37 5°C 5% CO 2 . Subsequently, this replaced by another one containing VAD3 VAD30 separately concentrations ranging 10 100 μL/mL, as well a control...
BACKGROUND Adenocarcinomas can be of several types, and MCF-7 is an adenocarcinoma human breast cell line useful as preclinical model to screen therapeutic agents such ultra-diluted Viscum album, European plant whose extract commonly used in cancer therapy. AIMS mesenchymal stem cells were evaluate the vitro cytotoxicity homoeopathic album 1x10-3 (VAD3). METHODS cultured for 24 hours controlled environment (37.5oC 5% CO2) 96-well plates. After this time, VAD3 was added culture medium...
The use of mesenchymal stem cells (MSC) in cytotoxicity tests is an in-vitro alternative model for predicting initial doses. Homeopathic medicines may stimulate the immune system to combat a pathology effectively and have been used over two centuries. Viscum album (VA) extracts are widely treatment cancer, due their immunomodulatory, cytotoxic pro-apoptotic properties. This study aimed evaluate growth kinetics canine MSC relation cytotoxicity, cell differentiation expression...
Background: Adenocarcinomas can be of several types and SK-BR-3 is one human breast adenocarcinoma cell line that useful as a preclinical model to screen for therapeutic agents such homeopathic Viscum album, European plant whose extract commonly used in cancer therapy.
Introduction: Studying adenocarcinoma cells and the new therapies for cancer is a promising area of interest. Adenocarcinoma breast can be several types MCF-7 are interest because they maintain characteristics similar to mammary epithelium, consolidated as an in vitro model study biology. As commonest cause death women worldwide, possibilities should studied, such homeopathic Viscum album (VA), medicine originated from plant whose extract has cytotoxic effects. In this study, were cultured...
ABSTRACT Despite the significance of adipose-derived stem cells in complementary and regenerative medicine, studies regarding clinical safety for allogeneic intravenous administration healthy dogs remain insufficiently conducted. This study aimed to assess cellular viability through laboratory microbiological evidence, along with genetic markers, addition evaluating clinic-laboratory dogs. To achieve this, two cell batches eight were included study. The results revealed positive markers...
Viscum album (VA), also known as Mistletoe, has various therapeutic properties, including analgesic, anti-inflammatory, and anticancer effects. It been used for treating different types of cancer, exhibiting proven efficacy against breast glioblastoma, carcinoma, other advanced-stage tumor types. Besides promoting improvements in the clinical condition, VA helps reduce side effects caused by conventional treatment, thereby offering patients a better quality life. Hence, objective this study...
Viscum album (VA), also known as Mistletoe, has various therapeutic properties, including analgesic, anti-inflammatory, and anticancer effects. It been used for treating different types of cancer, exhibiting proven efficacy against breast glioblastoma, carcinoma, other advanced-stage tumor types. Besides promoting improvements in the clinical condition, VA helps reduce side effects caused by conventional treatment, thereby offering patients a better quality life. Hence, objective this study...
A basic premise of reproductive physiology is that females have a finite and non-renewable stock germinative cells, which results in decrease capacity over time. For female bovines, further factor associated with this follicular puncture (ovum pickup - OPU), technique widely used for production embryos vitro. As such, it necessary to seek therapeutic or preventive options fertility problems, one potential option treatment mesenchymal stem cells (MSC), exercise paracrine effect combating...
Homeopathy has become increasingly known and used in various treatments, showing excellent clinical results. One of its most common indications is to help treat chronic diseases, directly improving patients' quality life, especially those with cancer. Hepatocellular carcinoma a disease that depends on different factors for development the success treatment. In this context, searching new therapeutic tools essential, homeopathy seems promising. Therefore, Anonna muricata (soursop/graviola)...
A ancilostomíase é uma parasitose gastrointestinal que acomete os animais domésticos. No Brasil, essa enfermidade tem como seus principais agentes etiológicos o Ancylostoma caninum e brazilienses. Além disso, doença possui cunho zoonótico pode infectar humanos, entram em contato com sua forma infectante, resultando infecção conhecida larva migrans cutânea (LMC) ou popularmente chamada de “bicho geográfico”. Com isso vista, a realização medidas preventivas para controlar parasitária...
This work evaluates the preservation of bovine placentomes using paraformaldehyde and glutaraldehyde at 4% solutions Karnovsky, Bouin Carnoy for 4, 12 24 hours fixation, room temperature or 4ºC, before inclusion in plastic resin paraffin. The best specimens was obtained after fixation with those containing aldehydes. With solution time 4 hours, while hours. Inclusion gave better results than paraffin, did not influence quality evaluation light microscopy.
Adenocarcinoma in breast can be of several types and PMC-42 MCF-7 cell lines are a well-established used vitro studies retaining much the breast's native phenotype. Viscum album, plant which extract has cytotoxic effects, is included brand-new class cancer therapies its ultra-diluted version promising area interest. The MTT assay was realized to evaluate potential calculate inhibitory concentration different concentrations album D30 (VAD30). results indicated that 60mL/mL, 37mL/mL 35ml/mL...
Viscum Album </em>(VA) has been widely used as adjuvant therapy in cancer. Its anticancer activity attributed to a combination of cytotoxic, immunomodulatory, and anti-inflammatory properties.
ABSTRACT This study aimed to evaluate the safety of allogeneic adipose-derived mesenchymal stromal cell (aASC) treatment in dogs with chronic kidney disease (CKD) at time infusions and during 120-day follow-up after last infusion. Five CKD received three intravenous approximately 1×106?10% aASCs per kilogram body weight 21-day intervals. Clinical laboratory evaluations were performed each 30 120 days Adverse effects assessed using clinical observations, analyses, owners’ answers about their...