A5082522927- Antimicrobial Peptides and Activities
- Probiotics and Fermented Foods
- Genomics and Phylogenetic Studies
- Biochemical and Structural Characterization
- Marine Sponges and Natural Products
- Identification and Quantification in Food
- Aquaculture disease management and microbiota
- Microbial Natural Products and Biosynthesis
- Electrospun Nanofibers in Biomedical Applications
- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Dental materials and restorations
- Oral microbiology and periodontitis research
- Coral and Marine Ecosystems Studies
- Insect and Pesticide Research
- Protein Hydrolysis and Bioactive Peptides
- Bacterial Genetics and Biotechnology
- Bone and Dental Protein Studies
- Bacillus and Francisella bacterial research
- Transgenic Plants and Applications
- Nail Diseases and Treatments
- Endodontics and Root Canal Treatments
- Insect Resistance and Genetics
- Toxin Mechanisms and Immunotoxins
- Escherichia coli research studies
Universidade Católica de Brasília
2018-2025
Oceanic environments are one of the largest sources bioactive molecules, due to high degree biodiversity and innumerable ecological relationships established between macro microorganisms found in different ecosystems these complex environments. Marine organisms being studied increasingly because they considered important producers biologically active peptides. Peptides extracted from marine have functions structures, when compared peptides isolated terrestrial sources, considering adaptive...
Multifunctional scaffolds with host defense peptides designed for regenerative endodontics are desirable nanobiotechnological tools dentistry. Here, different were tested use during the pulp revascularization process, including poly(vinyl alcohol)-PVA hydrogels or resins, collagen and alcohol) PVA/Chitosan (PVA/CS) nanofibers. Based on time to degradation (21 days), nanofibers chosen be incorporated ciprofloxacin IDR-1002 (each at 50 mg/g). Nanofibers containing had anti-biofilm activity...
Corals can be considered holobiont organisms, since they have an important symbiotic relationship with microbial communities such as zooxanthellae, bacteria, Archaea, fungi and viruses. It is to understand how those influence the health of corals environmental conditions could affect them. The present study aimed describe bacterial associated three Brazilian coral species, Millepora alcicornis, Mussismilia harttii Phyllogorgia dilatata, by a culture-independent method, using 16S rRNA gene...
Multidrug resistant bacteria infections have motivated the search for new therapeutics. The synergic effect of conventional antibiotics and lipopeptides pelgipeptin family was evaluated by Checkerboard method. Results indicate that association Pelgipeptin B C or chloramphenicol has a against multidrug strain; which may be due to variations on hydrophobicity mechanisms action molecules tested.
A Paenibacillus elgii strain isolated from soil samples Cerrado, Brazil, showed antimicrobial activity. Its genome sequence was acquired (GS20 FLX Titanium 454 platform) and comprises 108 contigs ( N 50 , 198,427 bp) 6,810 predicted sequences.
The need for discovering new compounds that can act selectively on pathogens is becoming increasingly evident, given the number of deaths worldwide due to bacterial infections or tumor cells. New multifunctional biotechnological tools are being sought, including present in spider venoms, which have high potential. work aims perform rational design and functional evaluation synthetic peptides derived from Lachesana tarabaevi toxin, known as latarcin-3a. antimicrobial activity was tested...
<abstract> Systemic mycoses have become a major cause of morbidity and mortality, particularly among immunocompromised hosts long-term hospitalized patients. Conventional antifungal agents are limited because not only their costs toxicity but also the rise resistant strains. Lipopeptides from <italic>Paenibacillus</italic> species exhibit antimicrobial activity against wide range human plant bacterial pathogens. However, potential these compounds important pathogens has yet been fully...
The use of mesenchymal stem cells (MSC) in cytotoxicity tests is an in-vitro alternative model for predicting initial doses. Homeopathic medicines may stimulate the immune system to combat a pathology effectively and have been used over two centuries. Viscum album (VA) extracts are widely treatment cancer, due their immunomodulatory, cytotoxic pro-apoptotic properties. This study aimed evaluate growth kinetics canine MSC relation cytotoxicity, cell differentiation expression...
Pelgipeptins, tridecaptins, and elgicins are among the antimicrobials produced by Paenibacillus elgii. Growth in complex media is commonly applied to obtain lipopeptides from culture's supernatant, but it requires further purification. This study aimed improve yield of pelgipeptins tridecaptins using chemically defined media. The kinetics antimicrobial lipopeptide were evaluated P. elgii AC13. Pelgipeptins detected supernatant culture pellet, mainly associated with cell debris or endospores....
Defensins are present in many organisms and divided into two evolutionary groups, termed cis- trans-defensins. Cis-defensins have only recently been reported bacteria, knowledge of these defensins is limited, with no family classification. Here, we describe the identification 74 cis-defensins from bacteria propose five classes for their We also report first NMR structure determination a Myxoccocus xanthus defensin, as well its silico expression analysis. Xanthusin-1 has unique among...
Aedes aegypti and Culex quinquefasciatus are vectors of numerous diseases worldwide public importance, such as arboviruses filariasis. The main strategy for controlling these is the use chemicals, which can induce appearance resistant insects. Bacillus thuringiensis (Bt) Lysinibacillus sphaericus (Ls) with larvicidal activity against arboviral-transmitting insects has been successful in many studies. In contrast, knowledge peptides insecticidal so far scarce. this work, 25 5 strains each...