A5014128486- Probiotics and Fermented Foods
- Identification and Quantification in Food
- Genomics and Phylogenetic Studies
- Microbial Natural Products and Biosynthesis
- Bacterial Genetics and Biotechnology
- Fungal Infections and Studies
- Nail Diseases and Treatments
- Bacteriophages and microbial interactions
- Escherichia coli research studies
- Bacillus and Francisella bacterial research
- Antifungal resistance and susceptibility
- Antibiotic Resistance in Bacteria
Universidade Católica de Brasília
2018-2024
Multidrug resistant bacteria infections have motivated the search for new therapeutics. The synergic effect of conventional antibiotics and lipopeptides pelgipeptin family was evaluated by Checkerboard method. Results indicate that association Pelgipeptin B C or chloramphenicol has a against multidrug strain; which may be due to variations on hydrophobicity mechanisms action molecules tested.
A Paenibacillus elgii strain isolated from soil samples Cerrado, Brazil, showed antimicrobial activity. Its genome sequence was acquired (GS20 FLX Titanium 454 platform) and comprises 108 contigs ( N 50 , 198,427 bp) 6,810 predicted sequences.
<abstract> Systemic mycoses have become a major cause of morbidity and mortality, particularly among immunocompromised hosts long-term hospitalized patients. Conventional antifungal agents are limited because not only their costs toxicity but also the rise resistant strains. Lipopeptides from <italic>Paenibacillus</italic> species exhibit antimicrobial activity against wide range human plant bacterial pathogens. However, potential these compounds important pathogens has yet been fully...
Pelgipeptins, tridecaptins, and elgicins are among the antimicrobials produced by Paenibacillus elgii. Growth in complex media is commonly applied to obtain lipopeptides from culture's supernatant, but it requires further purification. This study aimed improve yield of pelgipeptins tridecaptins using chemically defined media. The kinetics antimicrobial lipopeptide were evaluated P. elgii AC13. Pelgipeptins detected supernatant culture pellet, mainly associated with cell debris or endospores....