Lucas Souza dos Santos

ORCID: 0000-0002-1674-5133
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About
Contact & Profiles
Research Areas
  • Science and Education Research
  • Occupational Health and Burnout
  • Women's cancer prevention and management
  • Bacterial Genetics and Biotechnology
  • Antimicrobial Peptides and Activities
  • Plant-Microbe Interactions and Immunity
  • Healthcare during COVID-19 Pandemic
  • Youth, Drugs, and Violence
  • Cervical Cancer and HPV Research
  • Plant Pathogenic Bacteria Studies
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Probiotics and Fermented Foods
  • Evasion and Academic Success Factors
  • Genomics and Phylogenetic Studies
  • Regulation of Appetite and Obesity
  • Virology and Viral Diseases
  • Aquaculture disease management and microbiota
  • Electroconvulsive Therapy Studies
  • Plant nutrient uptake and metabolism
  • Adipokines, Inflammation, and Metabolic Diseases
  • Education during COVID-19 pandemic
  • Biochemical and Structural Characterization
  • Physical Education and Sports Studies
  • Bone and Dental Protein Studies
  • Escherichia coli research studies

Universidade de São Paulo
2021-2024

Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde
2023

Universidade do Vale do Paraíba
2023

Universidade Federal do Espírito Santo
2023

Universidade Federal de São Paulo
2019-2023

Universidade Católica de Brasília
2022-2023

Natura (Brazil)
2023

Brazilian Agricultural Research Corporation
2019-2022

Centro Universitário do Distrito Federal
2020-2022

Universidade Federal Fluminense
2019

Antimicrobial peptides (AMP) have received particular attention due to their capacity kill bacteria. Although much is known about them, are currently being further researched. A large number of AMPs been discovered, but only a few approved for topical use, promiscuity and other challenges, which need be overcome.AMPs diverse in structure. Consequently, they varied action mechanisms when targeting microorganisms or eukaryotic cells. Herein, the authors focus on linear peptides, particularly...

10.1080/17460441.2023.2173736 article EN Expert Opinion on Drug Discovery 2023-01-31

Measles is an acute febrile exanthematic disease of viral etiology, highly contagious, being the cause morbidity and mortality children in developing countries, whereas it has become rarer developed countries due to vaccination.Its differential diagnosis should be made with other childhood respiratory diseases such as influenza, rhinovirus adenovirus, rubella, roseola varicella.In tropical regions, performed dengue, zika chikungunya.Its clinical picture presents following phases: incubation,...

10.5935/1676-2444.20190035 article EN cc-by Jornal Brasileiro de Patologia e Medicina Laboratorial 2019-01-01

The C-terminal portion of the E protein, known as stem, is conserved among flaviviruses and an important target to peptide-based antiviral strategies. Since dengue (DENV) Zika (ZIKV) viruses share sequences in stem region, this study we evaluated cross-inhibition ZIKV by stem-based DV2 peptide (419–447), which was previously described inhibit all DENV serotypes. Thus, anti-ZIKV effects induced treatments with were tested both vitro vivo conditions. Molecular modeling approaches have...

10.3390/v15040839 article EN cc-by Viruses 2023-03-25

RESUMO As prevalências de depressão e ansiedade são elevadas entre universitários brasileiros. Este estudo avaliou a prevalência os fatores associados aos sintomas sugestivos (SSDs) (SSAs) servidores estudantes uma Universidade Federal brasileira no retorno das atividades presenciais após o isolamento social devido pandemia Covid-19. Utilizou-se um questionário autoaplicável, hospedado Google Forms, com dados sociodemográficos, hábitos vida acadêmicos, somado Inventários Depressão Ansiedade...

10.54033/cadpedv21n9-280 article PT Caderno Pedagógico 2024-09-24

The role of the iron–sulfur [Fe-S] cluster transcriptional regulator IscR in maintaining homeostasis bacteria is still poorly characterized many groups. Caulobacter crescentus and other Alphaproteobacteria have a single operon encoding biosynthesis enzymes. We showed that expression this increases iron starvation, but not oxidative stress, controlled mainly by IscR. Transcriptome analysis comparing an iscR null mutant strain with wild-type (wt) identified 94 differentially expressed genes...

10.3389/fmicb.2024.1463854 article EN cc-by Frontiers in Microbiology 2024-09-30

Mycobacterium tuberculosis (Mtb) has 11 Serine-Threonine Protein Kinases (STPK) that control numerous physiological processes, including cell growth, division, metabolic flow, and transcription. PknF is one of the Mtb STPKs has, among other substrates, two FHA domains (FHA-1 FHA-2) ATP-Binding Cassette (ABC) transporter Rv1747. Phosphorylation in T152 T210 located a non-structured linker connects Rv1747 considerate to be regulatory mechanism transporter. In this work, we resolved...

10.1016/j.crstbi.2021.07.001 article EN cc-by-nc-nd Current Research in Structural Biology 2021-01-01

Resumo -O ambiente acadêmico é um local onde há cobrança excessiva ocasionando no aumento dos transtornos de depressão e ansiedade podendo

10.18066/inic0112.23 article PT 2023-01-01

Resumo -A distribuição da depressão, já alta entre brasileiros e universitários, agravou-se durante o isolamento social oriundo COVID-19.Doravante, este trabalho visou avaliar a prevalência fatores associados aos sintomas sugestivos de depressão estudantes

10.18066/inic0095.23 article PT 2023-01-01

Anais do Congresso de Biomedicina da Região Norte: BIOMEDICINA: Inovação, Desafios e Perspectivas na Formação Biomédico (a) Norte (978-65-5941-940-1) - Papilomavírus Humano E Sua Vacina: Avaliação Do Status Conhecimento De Futuros Professores No Município Bragança, Pará

10.29327/1319040.1-4 article PT 2023-01-01

Na educação em saúde, o desenvolvimento de conhecimentos, hábitos e habilidades devem ser buscado visando a compreensão adoção um modo vida mais saudável. Nesse sentido, professor tem papel muito importante. Este estudo avaliou status do conhecimento sobre papilomavírus humano (HPV) sua vacina numa amostra universitários que estavam cursando licenciaturas (UL) indicou as lacunas serem ajustadas. transversal foi realizado com UL no município Bragança, Pará, norte Brasil. A técnica amostragem...

10.1016/j.bjid.2023.103106 article PT cc-by-nc-nd The Brazilian Journal of Infectious Diseases 2023-10-01
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