- Endodontics and Root Canal Treatments
- Oral microbiology and periodontitis research
- Dental Radiography and Imaging
- Dental materials and restorations
- dental development and anomalies
- Cleft Lip and Palate Research
- Bone and Dental Protein Studies
- Craniofacial Disorders and Treatments
- Congenital Ear and Nasal Anomalies
- Bone Metabolism and Diseases
- Mesenchymal stem cell research
- Geography and Environmental Studies
- Oral Health Pathology and Treatment
- Oral and Maxillofacial Pathology
- Drilling and Well Engineering
- Immune Response and Inflammation
- Fish biology, ecology, and behavior
- Dental Health and Care Utilization
- Biomarkers in Disease Mechanisms
- NF-κB Signaling Pathways
- Protease and Inhibitor Mechanisms
- Bone Tissue Engineering Materials
- Periodontal Regeneration and Treatments
- Oral and gingival health research
- Heat shock proteins research
University of Pittsburgh
2012-2025
Petrobras (Brazil)
2025
The University of Texas Health Science Center at Houston
2014-2023
Pontifícia Universidade Católica de Minas Gerais
2021
Hospital de Base
2020
Universidade Federal do Sul e Sudeste do Pará
2019
Vale Technological Institute
2019
Regenerative Medicine Institute
2016
Universidade de São Paulo
2014
Previous studies demonstrate that the balance between pro- and anti-inflammatory mediators determines stable or progressive nature of periapical granulomas by modulating osteoclastogenic factor RANKL its antagonist OPG. However, cytokine networks operating in development lesions are quite more complex than what simple versus mediators' paradigm suggests. Here we simultaneously investigated patterns Th1, Th2, Th9, Th17, Th22, Thf, Tr1 Tregs cytokines/markers expression human granulomas....
Abstract Aim To evaluate the cytotoxic effects of triple antibiotic paste ( TAP ), double DAP minocycline and calcium hydroxide their influence on cytokine m RNA expression levels human periodontal ligament HPDL ) fibroblasts. Methodology Triple paste, Ca(OH) 2 test samples were immersed in culture medium incubated at 37 °C for 24 48 h. cells seeded a density × 10 4 exposed to either media (negative control), 0.1% SDS (positive 24‐ or 48‐h elutes each material A multiparametric cytotoxicity...
Multifunctional scaffolds with host defense peptides designed for regenerative endodontics are desirable nanobiotechnological tools dentistry. Here, different were tested use during the pulp revascularization process, including poly(vinyl alcohol)-PVA hydrogels or resins, collagen and alcohol) PVA/Chitosan (PVA/CS) nanofibers. Based on time to degradation (21 days), nanofibers chosen be incorporated ciprofloxacin IDR-1002 (each at 50 mg/g). Nanofibers containing had anti-biofilm activity...
Matrix metalloproteinases (MMPs) play a key role in the tissue destruction characteristic of chronic periodontitis. The purpose this study was to investigate association MMP and TIMP polymorphisms with periodontitis two populations.A total 34 spanning 12 2 genes were genotyped 401 individuals from Brazil (99 cases 302 controls), 274 US (70 204 controls). Individuals considered if presenting at least three teeth exhibiting sites clinical attachment loss ≥ 5 mm different quadrants. Controls...
Liver cirrhosis (LC) is a heterogeneous liver disease, the last stage of fibrosis, and major risk factor for hepatocellular carcinoma (HCC). Our study aimed to evaluate expression microRNAs endothelial vascular growth (VEGFA) gene in LC HCC.The sample group consisted 46 tissue samples: 21 LC, 15 HCC, 10 non-tumoural non-cirrhotic (control group). MiRNAs were chosen based on mirDIP prediction database as regulators VEGFA gene. Gene VEGF miRNAs was quantified by real-time quantitative...