A5082555721- Air Quality and Health Impacts
- dental development and anomalies
- Sexual Differentiation and Disorders
- Climate Change and Health Impacts
- Cancer-related gene regulation
- Air Quality Monitoring and Forecasting
- Dental materials and restorations
- Metabolism and Genetic Disorders
- Liver Disease Diagnosis and Treatment
- DNA Repair Mechanisms
- Cardiac Fibrosis and Remodeling
- Genomics and Chromatin Dynamics
- T-cell and B-cell Immunology
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Hepatocellular Carcinoma Treatment and Prognosis
- Sirtuins and Resveratrol in Medicine
- Circular RNAs in diseases
- Viral Infections and Immunology Research
- Neonatal Health and Biochemistry
- Tissue Engineering and Regenerative Medicine
- BRCA gene mutations in cancer
- Endodontics and Root Canal Treatments
- Cancer-related molecular mechanisms research
- Bone and Dental Protein Studies
- Blood groups and transfusion
Xiamen Maternal and Child Health Hospital
2020-2022
Xiamen University
2020-2022
Sichuan University
2022
Children’s Hospital of Fudan University Xiamen Branch
2021
The University of Texas Health Science Center at Houston
2020
Fujian Medical University
2017
Hamilton Health Sciences
2016-2017
McMaster University
2016-2017
Guangxi University
2013
To investigate the utility and experience of neuroendoscopy in resection cerebellar vermis tumors. Retrospective analysis was conducted on clinical data tumors treated with German STORZ neuroendoscope within Department Neurosurgery at Guizhou Provincial People's Hospital Shanghai Children's Center from January 2021 to 2024. Among 18 patients, total achieved 16 cases, subtotal 1 case, biopsy case. Postoperative pathological revealed 9 cases medulloblastoma, 3 ependymoma, 5 astrocytoma...
Abstract Background The aim of this study was to investigate the effects Resveratrol (RSV) in rats with dilated cardiomyopathy (DCM). Methods Porcine cardiac myosin used set up rat model DCM. RSV (10 mg/kg RSV-L group and 50 RSV-H group) or vehicle administered DCM once daily from 28th day till 90th after first immunization. Cardiac function evaluated by echocardiographic analysis. deposition fibrous tissues hearts Masson picrosirius red staining. mRNA levels collagen type I (Col I), III...
Mutations in WNT10A have frequently been reported as etiologic for tooth agenesis (TA). However, the effects of variation on gene/protein function and contribution to TA phenotypes remain poorly understood. Here, we performed bioinformatic functional characterization analysis variants. In silico prediction variant was with VIPUR all missense variants Exome Aggregation Consortium database. Functional experiments were then selected previously associated TA. Expression vectors wild-type mutant...
Some studies have reported an association between the zinc-finger protein 350 (ZNF350), also known as and BRCA1-interacting with a Kruppel-associated box (KRAB) domain (ZBRK1), risks of breast cancer, although results remain controversial. A systematic search was conducted on PubMed, Web Science, EMBASE, Ovid, Chinese National Knowledge Databases, WanFang databases relevant keywords. Four five distinct populations involving 5824 cancer cases were used to conduct meta-analysis that summarizes...
To determine the functional effects of ATF1, WNT10B and GREM2 gene variants identified in individuals with tooth agenesis (TA).Stem cells from human exfoliated deciduous teeth (SHED) were used as an vitro model system to test effect TA-associated variants.Plasmid constructs containing reference mutant alleles for ATF1 rs11169552, rs833843 rs1414655 transfected into SHED characterization variants. Allele-specific changes transcription activity, protein expression, cell migration...
The fibrous texture in liver is one of important signs for interpreting the chronic diseases radiologists’ routines. In order to investigate usefulness various features calculated by computer algorithm on hepatic magnetic resonance (MR) images, 15 were from gray level co-occurrence matrix (GLCM) within a region interest (ROI) which was selected MR images with 6 stages fibrosis. By different combination as input vectors, classifier had performance staging Each tested Support Vector Machine...
The aim of this study was to investigate the effect costimulation blockade with cytotoxic T-lymphocyte-associated-antigen 4-immunoglobulin (CTLA4Ig) and anti-CD40L monoclonal antibody (anti-CD40L mAb) on an experimental autoimmune myocarditis (EAM) mouse model. Characteristics myocardial tissue were observed by hematoxylin eosin (H&E) staining. messenger RNA (mRNA) levels CTLA4, CD40L, IFN-γ, IL-4 detected real-time fluorescence quantitative polymerase chain reaction (RT-qPCR). Serum...
Long non-coding RNA LINC00511 is known to exacerbate lung adenocarcinoma (LUAD) progression. However, the specific mechanism by which affects LUAD progression has not been investigated as yet, and we aimed elucidate same in present study.The expression levels of LINC00511, microRNA miR-4739, pyrroline-5-carboxylate reductase 1 (PYCR1) were determined quantitative reverse transcription PCR Western blotting. The Cell Counting Kit-8 bromodeoxyuridine assays used evaluate cell proliferation....
The relationship between air pollution and public health has gained increasing attention in the past decade. Many time-series analyses have been conducted worldwide, including all major cities of United States, Europe, Asia. However, most current analysis study Ontario, Canada dates back to 2012 includes only a single city, calling need more recent at provincial scale. As result, we propose conduct Ontario then use hierarchical model pool results construct dose-response generate predictive...
Abstract Rationale: Turner syndrome (TS) is a genetic disorder associated with abnormalities of the X chromosome related to ovarian function, but whether it endometrial still not clear. Patient concerns: We report case 26-year-old Han Chinese woman TS and Xp11.2 deletion, presenting short final stature, hypofunction, unexplained cystic dilatation entire endometrium, thickening. Diagnoses: The patient was diagnosed deletion through cytogenetic analysis ultrasonic pathology. Interventions:...
The relationship between air pollution and public health has gained increasing attention in the past decade. Many time-series analyses have been conducted worldwide, including all major cities of United States, Europe, Asia. However, most current analysis study Ontario, Canada dates back to 2012 includes only a single city, calling need more recent at provincial scale. As result, we propose conduct Ontario then use hierarchical model pool results construct dose-response generate predictive...
To explore the clinical and genetic characteristics of a patient with 17-hydroxylase/17,20-lyase deficiency.The was infertile without contraception. Laboratory examination showed her chromosomal karyotype to be 46, XX. DNA sequencing performed detect variants CYP17A1 gene in family members.Sanger revealed that has carried homozygous variant c.1486C>T exon 8 gene, which resulted substitution arginine by cysteine (p.Arg496Cys). Her members were all heterozygotes for same variant.Homozygous...