A5101407619- Advanced biosensing and bioanalysis techniques
- Tracheal and airway disorders
- Spinal Fractures and Fixation Techniques
- Medical Imaging and Analysis
- Pregnancy and preeclampsia studies
- Carbon and Quantum Dots Applications
- Bacterial Identification and Susceptibility Testing
- Cancer-related molecular mechanisms research
- Cardiac Arrhythmias and Treatments
- Healthcare Quality and Management
- MicroRNA in disease regulation
- Orthopedic Surgery and Rehabilitation
- Spine and Intervertebral Disc Pathology
- Amoebic Infections and Treatments
- Platelet Disorders and Treatments
- Esophageal and GI Pathology
- Peptidase Inhibition and Analysis
- Atrial Fibrillation Management and Outcomes
- Electrochemical sensors and biosensors
- Colorectal Cancer Surgical Treatments
- Natural Products and Biological Research
- Antibiotic Resistance in Bacteria
- Pelvic and Acetabular Injuries
- Antimicrobial Resistance in Staphylococcus
- Scoliosis diagnosis and treatment
Shanghai Jiao Tong University
2025
Shanghai Ninth People's Hospital
2025
Wuhan Puai Hospital
2024
Fujian Provincial Hospital
2012-2024
Fujian Medical University
2015-2024
Union Hospital
2013-2024
Fudan University
2011-2024
Huadong Hospital
2024
Guiyang Medical University
2024
Central Committee of the Communist Party of China
2024
This study aimed to explore the effects of endometriosis (EMS)-derived exosomes and miR-301a-3p on polarization macrophages investigate involved molecular mechanism. The were isolated from ectopic endometrial tissues EMS patients normal human serum (NHS). Results transmission electron microscope Nanoparticle Tracking Analysis showed that both EMS-exosomes NHS-exosomes are about 80 nm microvesicles. Exosomal markers CD63 TSG101 abundantly expressed in NHS-exosomes. No negative marker Calnexin...
Abstract Background The aim of this study was to investigate the effects Resveratrol (RSV) in rats with dilated cardiomyopathy (DCM). Methods Porcine cardiac myosin used set up rat model DCM. RSV (10 mg/kg RSV-L group and 50 RSV-H group) or vehicle administered DCM once daily from 28th day till 90th after first immunization. Cardiac function evaluated by echocardiographic analysis. deposition fibrous tissues hearts Masson picrosirius red staining. mRNA levels collagen type I (Col I), III...
Healthcare organizations are under pressure to improve services because of an aging population and increasing healthcare demands. Lean management focuses on improving service quality efficiency the condition limited resources, but it may overlook patients' emotional needs experiences, especially in developing countries. This study advocates integrating medical humanities with lean develop a patient-centered model. The employs literature review discuss critical role frameworks, both...
ABSTRACT Staphylococcal enterotoxin B (SEB) is a major virulence factor for staphylococcal toxic shock syndrome (TSS). SEB activates large subset of the T lymphocytic population, releasing proinflammatory cytokines. Blocking SEB-initiated toxicity may be an effective strategy treating TSS. Using process known as systematic evolution ligands by exponential enrichment (SELEX), we identified aptamer that can antagonize with nanomolar binding affinity ( K d = 64 nM). The antagonist effectively...
Tumor-free surgical margin is crucial but challenging in breast-conserving surgery (BCS). Fluorescence imaging a promising strategy for navigation that can reliably assist the surgeon with visualization Of tumor real-time. Notably, finding an optimized fluorescent probe has been research topic. Herein, we developed novel near-infrared (NIR) based on tailored Hepatitis B Core virus-like protein (HBc VLP) and presented preclinical imaging-guided surgery.The RGD-HBc160 VLP was synthesized by...
Blue luminescent nitrogen-doped carbon nanodots (N-CDs) with pH-dependent properties were prepared from citric acid (CA), glutathione (GSH), and polyethylene polyamine (PEPA) using a two-step pyrolytic route.
To distinguish Methicillin-Resistant Staphylococcus aureus (MRSA) from Methicillin-Sensitive (MSSA) in the protein sequences level, test susceptibility to antibiotic of all isolates Quanzhou hospitals, define virulence factor and molecular characteristics MRSA isolates. MSSA Pfam were used extract feature vectors 188D, n-gram 400D. Weka software was applied classify two performance effect evaluated. Antibiotic testing 81 performed by Mérieux Microbial Analysis Instrument. The 65...
Abstract Gestational diabetes mellitus (GDM), defined as dysglycaemia that is detected during pregnancy for the first time, has become a global health burden. GDM was found to be correlated epigenetic changes, which would cause abnormal expression of placental genes. In present study, we performed multi‐omic weighted gene coexpression network analysis (WGCNA) systematically identify hub genes using both epigenome‐ and transcriptome‐wide microarray data. Two datasets (GSE70493 GSE70494) were...
The fabrication of a facile, sensitive, and versatile immunosensor for the quantification metallothionein-3 (MT-3) is proposed in this work. K3[Fe(CN)6]–chitosan–glutaraldehyde (K–CS–GA) conjugate prepared from K3[Fe(CN)6], chitosan glutaraldehyde was employed as redox-active signal source. Carbon nanodots (C-dots) were coupled with Nafion to form nanocomposite architecture layer carry antibodies (Abs). C-dots enhanced electrochemical response improve detection sensitivity. steps...
A FRET-based aptasensor for CEA detection was constructed by using upconversion nanoparticles as the energy donor and Au acceptor.
The emergence and prevalence of carbapenem-resistant Enterobacteriaceae (CRE) have drawn worldwide attention. Ceftazidime/avibactam (CAZ/AVI) gives us a valuable alternative strategy to treat CRE infections. Unfortunately, CAZ/AVI resistance could occur during treatment. CAZ/AVI-resistant Carbapenem-resistant Klebsiella pneumoniae (CR-KP) (KP137060) earlier CAZ/AVI-susceptible isolate (KP135194) from the same hospitalized patient were collected at Fujian Medical University Union Hospital...
Concomitant exotropia have obvious symptoms of eye discomfort in adults, and the presence ocular surface inflammation patients may be important mediators between concomitant dry eye. Oculus Keratograph comprehensive analyzer was performed to detect noninvasive tear break time, height, red index, while disease index schirmer I testing were made. The levels IL‐6, IL‐10, IL‐17A, IL‐12P70, INF‐ γ , TNF‐ α detected tears with healthy controls matched by age gender through Simoa technology. IL‐6...
Abstract Background Due to its unique mechanical characteristics, the incidence of subsequent fracture after vertebral augmentation is higher in thoracolumbar segment, but causes have not been fully elucidated. This study aimed comprehensively explore potential risk factors for this region. Methods Patients with osteoporotic segment who received from January 2019 December 2020 were retrospectively reviewed. divided into refracture group and non-refracture according occurrence refracture. The...
Background Tafamidis emerged as the first FDA-approved drug for treating termed amyloid fibrils. This study aims to analyze adverse events (AEs) related tafamidis from second quarter (Q2) of 2019 fourth (Q4) 2023 FDA event reporting system (FAERS) database.
In this present work, graphene quantum dots (GQDs) were handily prepared with citric acid by the pyrolysis method and used to fabricate an electrochemical sensor for simultaneous determination of acetaminophen (AC) ascorbic (AA) in compound preparation.