A5100634640- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Liver physiology and pathology
- Hepatocellular Carcinoma Treatment and Prognosis
- Wound Healing and Treatments
- Phytochemicals and Antioxidant Activities
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Nanoplatforms for cancer theranostics
- Natural product bioactivities and synthesis
- Neural dynamics and brain function
- Anesthesia and Neurotoxicity Research
- RNA modifications and cancer
- Apelin-related biomedical research
- Eicosanoids and Hypertension Pharmacology
- COVID-19 Clinical Research Studies
- Ferroptosis and cancer prognosis
- Traditional Chinese Medicine Analysis
- Seaweed-derived Bioactive Compounds
- RNA Interference and Gene Delivery
- Smart Agriculture and AI
- Phytochemistry and Biological Activities
- Chromatography in Natural Products
- Antimicrobial agents and applications
- Diabetes, Cardiovascular Risks, and Lipoproteins
Shanghai Ninth People's Hospital
2016-2025
Shanghai Jiao Tong University
2011-2025
Sichuan Cancer Hospital
2024
Robert Bosch (Germany)
2024
Xi'an Jiaotong University
2020-2023
Wuhan Third Hospital
2021-2023
Tongren Hospital
2021-2023
Huashan Hospital
2023
Fudan University
2023
Wuhan University of Science and Technology
2023
Current treatments for full-thickness skin injuries are still unsatisfactory due to the lack of hierarchically stimulated dressings that can integrate rapid hemostasis, inflammation regulation, and tissue remodeling into one system instead single-stage boosting. In this work, a multilayer-structured bioactive glass nanopowder (BGN@PTE) is developed by coating poly-tannic acid ε-polylysine onto BGN via facile layer-by-layer assembly as an integrative multilevel dressing sequential management...
Abstract Bioactive hydrogels with multifunctional properties have shown promising potential in promoting wound repair and skin tissue regeneration. The regulation on different stages of healing (hemostasis inflammation) is important for repair. Herein, a multiple coordination‐derived bioactive hydrogel (SGPA) anti‐inflammatory proangiogenic hemostatic capacity reported. SGPA prepared through facile metal coordination action based the sodium alginate, ions (Gd 3+ ), bisphosphate...
Abstract The inhibition of inflammation and the promotion early angiogenesis are paid much attention in skin tissue engineering. Citric acid‐based biomaterials widely used engineering due to their bioactive structure biocompatibility, but there few studies on investigating role mechanism wound repair regeneration. Herein, potential anti‐inflammation poly(octanediol‐citrate‐polyglycol) (POCG) copolymer is reported regulating repair. It found that POCG can modulate macrophages phenotype...
BACKGROUND Liver cirrhosis and portal hypertension (PHT) can lead to lymphatic abnormalities coagulation dysfunction. Because lymphangiogenesis may relieve liver PHT, the present study investigated gene expression alterations in system effectiveness of platelet-mediated improving PHT. AIM To investigate role preclinical PHT models. METHODS Immunohistochemistry transcriptome sequencing bile duct ligation (BDL) control samples were conducted reveal indicated signaling pathways. Functional...
Colon cancer is one of the most common gastrointestinal tumors in world. Currently, commonly used methods such as radiotherapy, chemotherapy and drug treatments are often ineffective have significant side effects. Here we developed a safe efficient biomaterials based anti-tumor nanoplatform (M@NPs/miR365), which was formed with poly (citrate-peptide) (PCP), miRNA365 mimic MC38 cell membrane (M). PCP could efficiently deliver miR365 into cells, promote apoptosis tumor cells regulate...
The primary objective of this study was to investigate the toxicological impact Dibutyl phthalate (DBP) on process liver fibrosis transitioning into cirrhosis and subsequent development portal hypertension (PHT) through mechanism epithelial-mesenchymal transition (EMT) mediated by ROS/TGF-β/Snail-1 signaling pathway. Carbon tetrachloride (CCl4) (1 mg/kg) introduced in adult rats oral feeding CCl4 CCl4+DBP groups twice a week for 8 weeks, another group. DBP group over following weeks. We...
Many plants associate with endophytic microbes that improve root phosphorus (P) uptake. Understanding the interactions between roots and endophytes can enable efforts to P utilization. Here, we characterize lateral of in a core collection 50 rapeseed (Brassica napus L.) genotypes differing sensitivities low conditions. With correlation analysis result bacterial abundance plant physiological indices rapeseeds, inoculation experiments on plates soil, identify one Flavobacterium strain (C2)...
Abstract The main objective was to establish a prognostic model utilising long non‐coding RNAs associated with disulfidptosis and cuproptosis. data for RNA‐Sequence clinicopathological information of Colon adenocarcinoma (COAD) were acquired from Cancer Genome Atlas. A constructed using Cox regression the Least Absolute Shrinkage Selection Operator method. model's predictive ability assessed through principal component analysis, Kaplan–Meier nomogram etc. identifying rates overall survival,...
Background: This study aims to compare survival outcome after receiving radiofrequency ablation (RFA) and surgical resection (SR) for solitary hepatocellular carcinoma (HCC) with size large as 5 cm. Methods: The SEER database was queried patients HCC tumors who were treated RFA or SR between 2004 2015. Univariate multivariate Cox analysis used assess the influence of potential variables on patients' outcome. Additionally, propensity score matching (PSM) multiple imputations (MI) sensitivity...
Abstract Background Increases in the levels of serum C-reactive protein (CRP) and creatinine (Cr) decreases those albumin (Alb) are commonly observed acute pancreatitis (AP). We aimed to evaluate efficacy Cr/Alb CRP/Alb ratios prediction surgical treatment effect AP patients. Methods This study retrospectively analyzed clinical data obtained from 140 patients who underwent debridement January 2008 November 2018 Shanghai Ruijin Hospital. The at admission before surgery were assessed analysis...