A5101409748- Dental Trauma and Treatments
- Endodontics and Root Canal Treatments
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Periodontal Regeneration and Treatments
- Bone and Dental Protein Studies
- Injury Epidemiology and Prevention
- Oral microbiology and periodontitis research
- Immune Response and Inflammation
- FOXO transcription factor regulation
- Facial Trauma and Fracture Management
- Tissue Engineering and Regenerative Medicine
- Reconstructive Surgery and Microvascular Techniques
- Urological Disorders and Treatments
- Bone Tumor Diagnosis and Treatments
- Bone Tissue Engineering Materials
- Dental Health and Care Utilization
- Genetic and rare skin diseases.
- Cancer-related molecular mechanisms research
- Tumors and Oncological Cases
- Oral Health Pathology and Treatment
- Dental Radiography and Imaging
- Oral and Maxillofacial Pathology
- Hedgehog Signaling Pathway Studies
China Medical University
2011-2024
University of Pennsylvania
2018-2021
Shenyang Center for Disease Control and Prevention
2018-2020
Stomatology Hospital
2014
Regenerative endodontic procedures (REPs) are a new option for the treatment of dental pulp or periapical diseases in permanent teeth with open apices. Histologically, tissues formed root canal after REPs mainly cementum- bone-like mineralised tissues, but not real dentine-pulp complex. Therefore, how to promote complex regeneration and improve clinical effects has become prominent research topic. Stem cells from apical papilla (SCAP) derived that can differentiate into primary odontoblasts...
ABSTRACT Chondrocytes play an essential role in fracture healing by producing cartilage, which forms anlage for endochondral ossification that stabilizes the callus. More recently it has been appreciated chondrocytes have capacity to produce factors may affect process. We examined of angiogenesis during and transcription factor forkhead box-O 1 (FOXO1), upregulates wound soft tissue. Closed fractures were induced experimental mice with lineage-specific FOXO1 deletion Cre recombinase under...
Abstract Objective This study investigated the effects of poly lactic‐co‐glycolic acid (PLGA) loaded with plasmid DNA encoding fibroblast growth factor‐2 (pFGF‐2) on human periodontal ligament cells (hPDLCs) in vitro and evaluated ability PLGA/pFGF‐2 scaffold to promote (PDL) regeneration a beagle dog teeth avulsion animal model. Background Growth factor play important roles PDL regeneration. PLGA is kind biodegradable biocompatible polymer that can be used as carrier deliver factors or...
Abstract Background Tooth avulsion represents the most severe form of dental trauma, necessitating tooth replantation as primary treatment. However, risk replacement root resorption (RRR) poses a significant threat to retention following replantation. This study preliminarily aimed investigate effect physiological occlusal force on RRR after avulsed teeth and explore potential underlying mechanisms. Methods Thirty-six 4-week-old male Sprague-Dawley rats underwent extraction immediate their...
Abstract Background/Aim The viability of periodontal ligament cells on the root surface is a major factor that influences healing replanted teeth. A suitable storage medium necessary to preserve avulsed teeth before replantation. Conditioned from placenta‐derived mesenchymal stem (PMSC‐CM) contains variety growth factors. aim this study was evaluate effectiveness PMSC‐CM as maintain cell Material and Methods Extracted premolars healthy humans were randomly stored in Hank's balanced salt...