A5101505936- Alzheimer's disease research and treatments
- Neuroscience and Neuropharmacology Research
- Traditional Chinese Medicine Studies
- Ocular Surface and Contact Lens
- Cholinesterase and Neurodegenerative Diseases
- TGF-β signaling in diseases
- Glaucoma and retinal disorders
- Stress Responses and Cortisol
- Acute Ischemic Stroke Management
- Neurogenesis and neuroplasticity mechanisms
- Systemic Lupus Erythematosus Research
- Monoclonal and Polyclonal Antibodies Research
- Cytokine Signaling Pathways and Interactions
- Growth Hormone and Insulin-like Growth Factors
- Circadian rhythm and melatonin
- Pulmonary Hypertension Research and Treatments
- Systemic Sclerosis and Related Diseases
- Neurological Disease Mechanisms and Treatments
- Ophthalmology and Eye Disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Acupuncture Treatment Research Studies
- Psoriasis: Treatment and Pathogenesis
- Galectins and Cancer Biology
- Cardiac Ischemia and Reperfusion
- IL-33, ST2, and ILC Pathways
Shenzhen University
2024
Southern Medical University Shenzhen Hospital
2024
Jinan University
2018-2024
Fujian University of Traditional Chinese Medicine
2024
Southern University of Science and Technology
2024
ShenZhen People’s Hospital
2004-2023
Fujian Medical University
2020-2023
Second Affiliated Hospital of Fujian Medical University
2021-2023
First Affiliated Hospital of Fujian Medical University
2020-2021
Hubei University of Chinese Medicine
2010-2018
Concomitant exotropia have obvious symptoms of eye discomfort in adults, and the presence ocular surface inflammation patients may be important mediators between concomitant dry eye. Oculus Keratograph comprehensive analyzer was performed to detect noninvasive tear break time, height, red index, while disease index schirmer I testing were made. The levels IL‐6, IL‐10, IL‐17A, IL‐12P70, INF‐ γ , TNF‐ α detected tears with healthy controls matched by age gender through Simoa technology. IL‐6...
Background Previous studies have revealed that Galectin-9 (Gal-9) acts as an apoptosis modulator in autoimmunity and rheumatic inflammation. In the present study, we investigated potential role of Gal-9 a biomarker patients with rheumatoid arthritis (RA), especially indicator functional limitations radiographic joint damage. Methods A total 146 RA 52 age- sex-matched healthy controls were included this study. Clinical data including disease activity, physical function, damage assessed....
This study aimed to observe the effects of acupuncture combined with trunk strengthening training on balance and gait abilities in stroke hemiplegic patients. Sixty patients were selected randomly divided into a treatment group control group, 30 each group. The received conventional rehabilitation exercises, while addition same interventions. Before after 8 weeks treatment, assessed using Holden Functional Ambulation Categories Berg Balance Scale, measurements taken for step length, width,...
A 59-year-old woman was admitted to our hospital for the management of refractory gastroesophageal reflux disease (GERD). Gastroscopy, ascertaining presence GERD, revealed a manifestation classified as LA-C, accompanied by conspicuous abnormality in flap valve, graded Type III ([Fig. 1]). Dynamic monitoring unveiled an acid exposure time 32%, DeMeester score 144.9.
Pancreatic cancer is one of the most common malignancies worldwide. This study aimed at searching possible genetic mutations and value novel gene mutation in DNA damage-inducible transcript 4 (DDIT4) signaling pathway pancreatic cancer. Polymerase chain reaction (PCR) was performed to amplify sequences DDIT4 from patients with ductal adenocarcinoma. In addition, we used IHC detect expression level different types mutation. Double-labeled immunofluorescence employed explore levels DDIT4/LC3...
This study found that recruitment of alveolar macrophages and neutrophils was markedly increased in the mice transgenic for human IL-37b (IL-37tg) with heavier pneumococcal burden, resulting necrotizing pneumonia augmented death infiltrating neutrophils, leading to enhanced inflammation, tissue damage, mortality.
Introduction. The advances in cerebral ischemia treatment have resulted a larger proportion of patients get the benefits rebuilding blood flow to brain. Then, ischemia-reperfusion injury has emerged as new essential problem. Dectin-1 plays an important role by regulating function immune cells. Methods. C57BL/6 was blindly divided into four groups including sham-operated group and three different kinds middle artery occlusion (MCAO) (after 6 hours, 12 24 hours after plug removal). protein...
Tau is a neuronal microtubule-associated protein and its functions are modulated by site-specific phosphorylation. Expression of phosphorylated tau decreases with the development brain, high levels phosphorylation correlate presence dynamic microtubule during periods plasticity in developing brain. Rat brains different ages (newborn, one week, month, three months old) were used to study distribution unphosphorylated dentate gyrus hippocampus development. Double immunofluorescence staining...
Abstract Persistent corneal pain ( PCP ) has excellent research prospects, especially the central sensitization mechanism of trigeminal nerve, which is involved in migraine, pain, and neuralgia. The cornea dense sensory innervation, repeated neuropathic been associated with nerve sensitization, induced PCP. calcitonin gene‐related peptide CGRP conduction, injury protection, immune homeostasis. A high level maintains perception protects epithelial cells. However, a persistently causes...
Abstract Background Prior studies indicated improved survival in systemic sclerosis-associated pulmonary arterial hypertension (PAH) patients, but trends lupus erythematosus-associated PAH (SLE-PAH) remained unclear. Methods Analysing SLE-PAH patients from the nationwide CSTAR-PAH cohort, we divided them into two cohorts: A (2011-2016) and B (2016-2021), based on baseline right heart catheterization dates. We compared clinical characteristics, mortality, treatment outcomes between these...