A5101995624- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Head and Neck Anomalies
- Radiomics and Machine Learning in Medical Imaging
- Neuroendocrine Tumor Research Advances
- Thyroid Disorders and Treatments
- Nanoparticle-Based Drug Delivery
- Viral Infections and Immunology Research
- Toxin Mechanisms and Immunotoxins
- Consumer Behavior in Brand Consumption and Identification
- Emotional Intelligence and Performance
- AI in cancer detection
- MRI in cancer diagnosis
- Hepatocellular Carcinoma Treatment and Prognosis
- Cytomegalovirus and herpesvirus research
- Global Cancer Incidence and Screening
- Electrospun Nanofibers in Biomedical Applications
- Intestinal and Peritoneal Adhesions
- Nanoplatforms for cancer theranostics
- Organ Transplantation Techniques and Outcomes
- Hemostasis and retained surgical items
- Surgical Sutures and Adhesives
- Medical and Biological Sciences
Chinese PLA General Hospital
2017-2025
Chinese People's Liberation Army
2021-2023
Nankai University
2021-2023
Hainan Branch of People's Liberation Army General Hospital
2021
Background: Papillary thyroid microcarcinoma (PTMC) typically carries an excellent prognosis regardless of the treatment option pursued. Radiofrequency ablation (RFA) for disease has been utilized benign lesions and in patients who are poor surgical candidates cancers with compression symptoms, but efficacy limitations RFA as first-line therapy PTMC not described adequate detail. The purpose our study was to investigate versus thyroidectomy terms efficacy, oncologic outcomes, quality life,...
Radiofrequency ablation (RFA) has gained increasing interest as a minimally invasive procedure to treat low-risk papillary thyroid carcinoma (PTC). Considering the indolent nature of this disease, studies in large populations with long follow-up would be invaluable further substantiate effectiveness RFA.
To report more than 5-year outcomes of ultrasound-guided thermal ablation (TA) for patients with solitary low-risk papillary thyroid microcarcinoma (PTMC) in a large multicenter cohort.TA, including radiofrequency (RFA) and microwave (MWA) have been used PTMC who refuse surgery or active surveillance. However, its clinical value remains controversial.This retrospective study included 474 treated TA (357 RFA; 117 MWA) from 4 centers followed up at least 5 years. Disease progression lymph node...
Abstract: In the current study, we synthesized prostate cancer-targeting poly(lactide- co -glycolic acid) (PLGA) nanobubbles (NBs) modified using A10-3.2 aptamers targeted to prostate-specific membrane antigen (PSMA) and encapsulated paclitaxel (PTX). We also investigated their impact on ultrasound (US) imaging therapy of cancer. PTX-A10-3.2-PLGA NBs were developed water-in-oil-in-water (water/oil/water) double emulsion carbodiimide chemistry approaches. Fluorescence together with flow...
Ultrasound-guided radiofrequency ablation (RFA) has been used in patients with papillary thyroid carcinoma (PTC) who refuse surgery or active surveillance. However, the long-term outcomes are still limited. This study aimed to evaluate clinical of RFA for solitary T1N0M0 PTC a large cohort over more than 5-year follow-up period.This retrospective included 358 were treated and followed at least 5 years. The bipolar procedure was performed using hydrodissection technique, transisthmic...
Ultrasound (US)-guided radiofrequency ablation (RFA) has been considered as an alternative to surgery or active surveillance for papillary thyroid microcarcinoma (PTMC). However, little is known about the long-term outcomes of RFA in comparison with unilateral multifocal PTMC.This work aims report between vs PTMC over a more than 5-year follow-up period.This was retrospective study at primary care center median period 72.9 months. A total 97 patients were treated (RFA group, n = 44) (surgery...
Ultrasonography-guided radiofrequency ablation (RFA) is used to treat small low-risk papillary thyroid carcinoma (PTC) and has achieved favorable results. However, few studies have compared the outcomes of T1aN0M0 T1bN0M0 PTC treated with ultrasonography-guided RFA. The objective this study was compare patients receiving RFA for solitary retrospectively.Patients or between April 2014 December 2019 were retrospectively reviewed. All ineligible refused surgery. Our institutional review board...
Background: The criteria for determining technical efficacy of thermal ablation papillary thyroid carcinoma (PTC) are not clearly defined. We analyzed the involution process zone with clear pathologic results on core-needle biopsy (CNB) to clarify relationship between sonographic changes and findings. Methods: This retrospective cohort study included 382 patients unifocal T1N0M0 PTC who underwent radiofrequency (RFA) May 2014 August 2021. Patients a single (recommended at 3 or 6 months T1a...
Objectives This study aims to summarise the features and trends of thyroid carcinoma in past two decades China. Design, setting participants Clinical data obtained from 10 798 patients treated by thyroidectomy 1994 2015 at Department General Surgery People’s Liberation Army Hospital, Beijing, China were retrospectively analysed. Outcome measures Incidence histopathological cancer compared risk factors for local lymph node metastasis Results Our indicated a significant increase detection...
Purpose To evaluate the efficacy and safety of ultrasonography (US)-guided radiofrequency ablation (RFA) for treating T2N0M0 papillary thyroid cancer (PTC).Methods This retrospective study was approved by ethics committee Chinese PLA General Hospital (S2019-211-01). Twelve patients with PTC (five men seven women a mean age 41.0 ± 9.2 years (range, 21–61 years)), who were not eligible or refused surgery, included in our study. RFA performed moving-shot technique, area exceeded tumor edge at...
Objective This retrospective study aimed to examine the benefits and complications of radiofrequency ablation (RFA) in patients with papillary thyroid microcarcinoma (PTMC) isthmus.Methods included PTMC isthmus treated at Chinese People's Liberation Army hospital from 05/2014 05/2018. The were divided into RFA total thyroidectomy (TT) groups. outcomes operation-related complications, rate recurrence, metastasis rate, carcinoma-specific questionnaire quality life (THYCA-QOL).Results Among 218...
Background About 3–9.2% of papillary thyroid carcinomas (PTC) are found in the isthmus, which has unique anatomic properties, making treatment more challenging. The aim this study was to evaluate and undesirable effects ultrasound-guided radiofrequency ablation (RFA) for PTC isthmus. Methods This retrospective case series assessed 112 patients with single microcarcinoma pathologically diagnosed before RFA at General Hospital Chinese PLA 2014–2018. Follow-up performed by contrast-enhanced...
We aimed to compare the efficacy and safety of radiofrequency ablation (RFA) that surgical resection (SR) in patients with T1bN0M0 papillary thyroid carcinoma (PTC) different age groups.Totally, 204 an isolated, solitary, intrathyroidal PTC, who underwent either RFA (n=94) or SR (n=110) between April 2014 December 2019, were retrospectively enrolled divided into two subgroups according (<45 years, ≧45 years). Patients pathologically aggressive advanced lesions excluded from study. Tumor...
To evaluate the efficacy and safety of radiofrequency ablation for low-risk papillary thyroid microcarcinoma (PTMC) in patients aged 55 years or older.This retrospective study included 95 older who underwent (RFA) PTMCs between June 2014 January 2019. Incidence duration postoperative complications were recorded evaluated. Tumor volume reduction rate (VRR) changes calculated. Patients also closely monitored tumor recurrence, regrowth, lymph node metastasis.All nodules completely ablated. The...
Authors: Bing Wang, Zheng Wan, Mingbo Zhang, Fengxia Gong, Linlin Yukun Luo, Jing Yao, Chen Li, Wen Tian
Maintaining an optimal thyroid stimulating hormone (TSH) level is important in the postoperative management of papillary carcinoma (PTC). However, there little evidence for TSH target levels patients undergoing radiofrequency ablation (RFA). This study aimed to determine low-risk who underwent RFA.This retrospective propensity score-matched cohort included with PTC RFA from January 2014 December 2018. The were categorized into two groups based on range levels: low (≤2 mU/L) and high (>2...
To summarize ultrasound features associated with medullary thyroid carcinoma (MTC) and investigate the predictive value of ultrasonography in preoperative diagnosis MTC.The sonographic clinical data were studied a series nodules histologically proven as MTC collected from January 1993 to 2013.A total 86 patients (92 MTC) enrolled study an average age (47±12) years.Among MTCs, 21.7%(20/92) excluded because missing remained 78.3%(72/92) had complete diameter (2.1±1.3) cm.The common US findings...
Abstract Purpose To evaluate the outcomes of radiofrequency ablation (RFA) for papillary thyroid microcarcinoma (PTMC) adjacent to trachea and compare those with PTMC distant from trachea. Methods This retrospective study reviewed patients who underwent RFA solitary low-risk between June 2014 July 2020. Patients were categorized into A group (PTMC trachea) (n = 211) D 790). The volume, volume reduction ratio (VRR), tumor disappearance, complication, disease progression assessed compared...
To explore the efficacy of homemade hemostatics injected gelatin matrix (HIGM) for immediately treating blunt hepatic trauma in canine model without additional pressure.A total 27 commercial hybrid dogs underwent celiotomy to establish after general anesthesia. The were prospectively randomized into 3 groups: treatment group (n=9, with direct application hemostat), positive control thrombin solution), and negative 0.9% normal saline). Time hemostasis intra-abdominal blood loss recorded,...