- Ultrasound Imaging and Elastography
- Photoacoustic and Ultrasonic Imaging
- Ultrasound and Hyperthermia Applications
- Thyroid Cancer Diagnosis and Treatment
- Reproductive System and Pregnancy
- Immune Cell Function and Interaction
- Radiomics and Machine Learning in Medical Imaging
- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- MRI in cancer diagnosis
- Immune Response and Inflammation
- Pancreatic and Hepatic Oncology Research
- Breast Lesions and Carcinomas
- Erythrocyte Function and Pathophysiology
- Elasticity and Material Modeling
- Breast Cancer Treatment Studies
- Scoliosis diagnosis and treatment
- Neuroendocrine Tumor Research Advances
- Ultrasound and Cavitation Phenomena
- Blood properties and coagulation
- Gastrointestinal motility and disorders
- Ultrasonics and Acoustic Wave Propagation
- Helicobacter pylori-related gastroenterology studies
- T-cell and B-cell Immunology
- Spinal Fractures and Fixation Techniques
Ruijin Hospital
2010-2025
Shanghai Jiao Tong University
2014-2024
Tongren Hospital
2016-2024
Zhejiang Chinese Medical University
2024
Smith-Kettlewell Eye Research Institute
2023
Stanford University
2021-2023
Shenzhen University
2014-2023
Nanjing Drum Tower Hospital
2023
Tianjin Medical University Cancer Institute and Hospital
2020-2022
Tianjin Medical University
2022
Elastography ultrasound (EUS) imaging is a vital modality. The current use of EUS faces many challenges, such as vulnerability to subjective manipulation, echo signal attenuation, and unknown risks elastic pressure in certain delicate tissues. hardware requirement also hinders the trend miniaturization equipment. Here we show cost-efficient solution by designing deep neural network synthesize virtual (V-EUS) from conventional B-mode images. A total 4580 breast tumor cases were collected 15...
Paclitaxel (PTX) is one of the most widely used clinical antitumour drugs in chemotherapy nowadays. Its effect on immune system has become a hot spot research recent years. Here, we demonstrated that PTX not only decreased percentage CD4+Foxp3+ regulatory T (Treg) cells both vitro and vivo but also impaired cell viability cytokine production Treg rather than CD4+Foxp3- effector (Teff) cells. As been reported to mimic activity LPS trigger toll-like receptor 4 (TLR4) signalling pathway...
To evaluate inter- and intra- scan mode scanner repeatability reproducibility of radiomics features within between single-energy CT (SECT) dual-energy (DECT).A standardized phantom with sixteen rods clinical-relevant densities was scanned on seven DECT-capable scanners three SECT-only scanners. The acquisition parameters were selected to present typical abdomen-pelvic examinations the same voxel size. Images SECT at 120 kVp corresponding kVp-like virtual monochromatic images (VMIs) in DECT...
Diffusion-weighted imaging (DWI)-based virtual MR elastography (DWI-vMRE) in the assessment of breast lesions is still research stage.
This paper presents the use of hydrodynamic cavitation and ultrasonic technologies for treating rhodamine B (RhB) in simulated wastewater. Various parameters each technology that influence RhB degradation rate were compared optimized. The results showed optimal conditions determined by single-factor method as follows: inlet pressure, 0.4 MPa; initial concentration, 10 mg L-1; reaction temperature, 30 °C; pH value, 3. was 38.7%. In addition, response surface methodology power, 850 W; time,...
A growing body of evidence links chronic obstructive pulmonary disease (COPD) to gastroesophageal reflux (GERD). In spite the lack understanding specific cause-effect relationship between COPD and GERD, GERD has been shown be a significant predictor acute exacerbations COPD. this study, we examined evolution over past decades provided valuable insights into topic.The Web Science Core Collection (WoSCC) was searched since its inception until 19 August 2022 obtain publications related GERD....
The microRNA miR-221-3p has previously been found to be an underlying biomarker of pancreatic cancer. However, the mechanisms its role in cancer pathogenesis, proliferation capability, invasion ability, drug resistance and apoptosis clinicopathological value have not thoroughly studied.Based on microarray miRNA-sequencing data extracted from Gene Expression Omnibus (GEO), Cancer Genome Atlas (TCGA), relevant literature, real-time quantitative PCR (RT-qPCR), we explored features expression...
Objectives To compare the sonographic results, clinicopathologic characteristics, and biomarkers in pure ductal carcinoma situ (DCIS) of breast DCIS with microinvasion. Methods A total 218 patients pathologically proven based on sonography our hospital (2009–2013) were retrospectively enrolled. Clinicopathologic characteristics examined. Grayscale results investigated according to American College Radiology Breast Imaging Reporting Data System lexicon, color Doppler was used assess...
Wnt1 inducible signaling pathway protein-1 (WISP1) may play an important role in promoting carcinogenesis. However, the biological function and underlying mechanism of WISP1 pancreatic carcinogenesis still remains enigmatic. In this study, immunochemistry staining showed that protein levels were more significantly upregulated ductal adenocarcinoma (PDAC) tissues with Tp53 mutation than PDAC wild-type. addition, a significant correlation was observed between increased malignant phenotype...
BACKGROUND The objective of this study was to compare the sampling efficiency ultrasound‐guided fine‐needle aspiration (FNA) and capillary (FNC) in thyroid nodules, which authors specifically analyzed influence nodule size. METHODS This included 280 nodules 275 consecutive patients. were divided into 4 size subgroups: ≤5.0 mm, from 5.1 10.0 10.1 20.0 >20.0 mm. Each sampled by both FNA FNC. final cytopathologic findings reported. smears scored then categorized as diagnostically inadequate,...
Axillary lymph node (ALN) status is a key prognostic factor in patients with early-stage invasive breast cancer (IBC). The present study aimed to develop and validate nomogram based on multimodal ultrasonographic (MMUS) features for early prediction of axillary metastasis (ALNM). A total 342 IBC (240 the training cohort 102 validation cohort) who underwent preoperative conventional ultrasound (US), strain elastography, shear wave elastography contrast-enhanced US examination were included...
To appraise the quality of guidelines on intravenous iodinated contrast media (ICM) use in patients with kidney disease, and to compare recommendations among them. We searched four literature databases, eight guideline libraries, ten homepages radiological societies identify English Chinese ICM disease published between January 2018 June 2023. The was assessed Scientific, Transparent, Applicable Rankings (STAR) tool. Ten were included, a median STAR score 46.0 (range 28.5-61.5). performed...
The EI24 autophagy-associated transmembrane protein is frequently associated with tumor growth and patient survival. In the present study, we found that was downregulated in pancreatic ductal adenocarcinoma (PDAC) tissues compared adjacent normal cancer cell differentiation. Overexpression of suppressed vitro vivo induced cycle S phase arrest, no impact on caspase-dependent apoptosis. overexpression also resulted reduced c-Myc expression, an oncogene PDAC, accompanied increased LC3B-II...