A5100604071- Research in Cotton Cultivation
- Plant Virus Research Studies
- Ear Surgery and Otitis Media
- Neurofibromatosis and Schwannoma Cases
- Plant and Fungal Interactions Research
- Tracheal and airway disorders
- Meningioma and schwannoma management
- Facial Nerve Paralysis Treatment and Research
- Hearing, Cochlea, Tinnitus, Genetics
- Head and Neck Surgical Oncology
- Pharmaceutical Practices and Patient Outcomes
- Anesthesia and Pain Management
- Venous Thromboembolism Diagnosis and Management
- Glycosylation and Glycoproteins Research
- Pelvic and Acetabular Injuries
- Spine and Intervertebral Disc Pathology
- Vestibular and auditory disorders
- Surgical Simulation and Training
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Plant Reproductive Biology
- Pancreatic function and diabetes
- Vascular Anomalies and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Cancer Immunotherapy and Biomarkers
- RNA modifications and cancer
Barts Health NHS Trust
2016-2025
University of California, Irvine
2020-2025
Princess Margaret Cancer Centre
2025
Royal London Hospital
2016-2025
University of York
2023-2024
Chapman University
2024
Oxford Nanopore Technologies (United Kingdom)
2024
Hull York Medical School
2023-2024
University of Illinois Chicago
2021-2024
University of Louisville
2024
Epithelial permeability is often increased in inflammatory bowel diseases. We hypothesized that perturbed mitochondrial function would cause barrier dysfunction and hence epithelial mitochondria could be targeted to treat intestinal inflammation. Mitochondrial was induced human colon-derived cell lines or colonic biopsy specimens using dinitrophenol, assessed by transepithelial flux of Escherichia coli with without mitochondria-targeted antioxidant (MTA) cotreatment. The impact antioxidants...
Abstract BACKGROUND: Hospital‐acquired (HA) venous thromboembolism (VTE) is a common source of morbidity/mortality. Prophylactic measures are underutilized. Available risk assessment models/protocols not prospectively validated. OBJECTIVES: Improve VTE prophylaxis, reduce HA VTE, and validate risk‐assessment model. DESIGN: Observational design. SETTING: Academic medical center. PATIENTS: Adult inpatients on medical/surgical services. INTERVENTIONS: A simple linked to menu preferred...
Abstract BACKGROUND: Structured subcutaneous insulin order sets and protocols are widely advocated. The intervention effects not well reported. OBJECTIVE: Assess the impact of these interventions on use patterns, hypoglycemia, glycemic control. DESIGN: Prospective observational. SETTING: 400‐bed academic center. PATIENTS: Adult non‐critical care inpatients with diabetes or hyperglycemia point‐of‐care (POC) glucose testing. INTERVENTIONS: orders, management algorithm. MEASUREMENTS: Percent...
Patients with kidney disease are at risk for adverse events due to improper medication prescribing. Few randomized controlled trials of clinical decision support (CDS) utilizing dynamic assessment patients' function improve prescribing patients have been published.We developed a CDS tool 20 medications within commercial electronic health record. Our system detected scenarios in which drug discontinuation or dosage adjustment was recommended adult impaired renal the ambulatory and acute...
Objective: The relationship of cognitive dysfunction and vestibular has been established by various studies. However, the available Patient-Reported Outcome Measures questionnaires that address main complaint fail to highlight this domain in patient population. objective study was quantify compare impairment using a validated questionnaire across several diagnoses. Study Design: Cross-sectional 186 patients presenting tertiary care clinic with diagnosis migraine, Meniere’s disease (MD),...
<title>Abstract</title> <bold>Background</bold>: Epithelial ovarian cancer (EOC) is characterized by a pattern of relapse and progression through successive recurrences, with increasing chemotherapy resistance. This highlights an urgent need for novel treatment strategies. Survivin, tumor-associated antigen, highly expressed in cancer, making it promising target immunotherapy. Designed to survivin-expressing tumor cells, Maveropepimut-S (MVP-S) DPX-based vaccine immunotherapy that induces...
ABSTRACT Background: Although posterior lumbar fusions (PLFs) have risen in popularity due to minimally invasive techniques and favorable outcomes, complications still arise. Studies show relatively constant rates of postoperative from 2006 2016, but there are limited studies evaluating outcomes after 2016. Consequently, we aim investigate trends for PLFs 2009 2022. Methods: The American College Surgeons National Surgical Quality Improvement Program was queried single-level between Patients...
Background.The TAM receptors (tyro3, axl and mer) their ligands (vitamin K-dependent proteins-Gas6 Protein S) are crucial modulators of inflammation, which may be relevant in chronic kidney disease (CKD).Gas6 have multiple roles mediating vascular atherosclerosis injury, thrombosis yet nothing is known about the Gas6-axl pathway humans with CKD.Given prevalence inflammation this population, we measured patients various levels renal function.Methods.Gas6 protein S were quantified plasma by...
Systemic lupus erythematosus (SLE or lupus) (OMIM: 152700) is a chronic autoimmune disease with debilitating inflammation that affects multiple organ systems. The STAT1–STAT4 locus one of the first and most highly replicated genetic loci associated risk. We performed fine-mapping study to identify plausible causal variants within increased Using complementary frequentist Bayesian approaches in trans-ancestral Discovery Replication cohorts, we found variant whose association risk supported...
Whole-spine magnetic resonance imaging (MRI) has been recommended in the preoperative evaluation of patients with neurofibromatosis type 1 (NF-1). However, no large study identified role MRI classification and management this condition. A retrospective 27 NF-1, presenting spinal deformity, who were investigated plain radiographs whole-spine MRI, was conducted to determine NF-1 deformity. The medical records, radiographs, studies neurologically intact had followed for a minimum 2 years,...
Journal Article Revision of the genetics hairiness-smoothness system Gossypium Get access Joshua A. Lee The author is geneticist, USDA-ARS and professor Crop Science, North Carolina State University, Raleigh NC 27695. Contribution from USDA-ARS, Agricultural Research Service, University journal series paper no. 9149. Search for other works by this on: Oxford Academic PubMed Google Scholar Heredity, Volume 76, Issue 2, March 1985, Pages 123–126,...
Journal Article THE GENOMIC ALLOCATION OF PRINCIPAL FOLIAR‐GLAND LOCI IN GOSSYPIUM HIRSUTUM AND BARBADENSE Get access Joshua A. Lee North Carolina State University Raleigh Search for other works by this author on: Oxford Academic Google Scholar Evolution, Volume 19, Issue 2, 1 June 1965, Pages 182–188, https://doi.org/10.1111/j.1558-5646.1965.tb01706.x Published: 01 1965 history Accepted: November 1964