A5009330455- Cardiac Arrest and Resuscitation
- Trauma and Emergency Care Studies
- Emergency and Acute Care Studies
- Traumatic Brain Injury Research
- Mechanical Circulatory Support Devices
- Injury Epidemiology and Prevention
- Congenital Heart Disease Studies
- Respiratory Support and Mechanisms
- Disaster Response and Management
- Dialysis and Renal Disease Management
- Cardiac Valve Diseases and Treatments
- Diabetes Treatment and Management
- Trauma Management and Diagnosis
- Aortic Disease and Treatment Approaches
- Neuropeptides and Animal Physiology
- Intensive Care Unit Cognitive Disorders
- Aortic aneurysm repair treatments
- Heart Rate Variability and Autonomic Control
- Heart Failure Treatment and Management
- Eicosanoids and Hypertension Pharmacology
- Peptidase Inhibition and Analysis
- Sepsis Diagnosis and Treatment
- Inflammatory mediators and NSAID effects
- Vascular anomalies and interventions
- Family and Patient Care in Intensive Care Units
Soka Municipal Hospital
2011-2024
Kanazawa University Hospital
2014-2024
Sapporo City General Hospital
2005-2024
Showa University
2024
Kanazawa University
2011-2023
Yawata Medical Center
2012-2021
Komatsu (Japan)
2012-2021
Saitama Prefecture
2016-2018
Ono Pharmaceutical (Japan)
2014-2016
Disco (japan)
2016
Background The determination of appropriate duration in‐the‐field cardiopulmonary resuscitation ( CPR ) for out‐of‐hospital cardiac arrest OHCA patients is one the biggest challenges emergency medical service providers and clinicians. before termination remains unclear may differ based on initial rhythm. We aimed to determine relationship between post‐ outcomes. Methods Results analyzed records 17 238 (age ≥18 years) who achieved prehospital return spontaneous circulation. Data were...
Background The impact of dispatcher‐assisted bystander cardiopulmonary resuscitation ( CPR ) on neurological outcomes in children is unclear. We investigated whether shows favorable (Cerebral Performance Category scale 1 or 2) with out‐of‐hospital cardiac arrest OHCA ). Methods and Results Children (n=5009, age<18 years) were selected from a nationwide Utstein‐style Japanese database (2008–2010) divided into 3 groups: no (n=2287); dispatcher instruction (n=2019); without (n=703) groups....
Abstract Introduction Few clinical trials have provided evidence that epinephrine administration after out-of-hospital cardiac arrest (OHCA) improves long-term survival. Here we determined whether prehospital would improve 1-month survival in OHCA patients. Methods We analyzed the data of 209,577 patients; were prospectively collected a nationwide Utstein-style Japanese database between 2009 and 2010. Patients divided into initial shockable rhythm ( n = 15,492) non-shockable 194,085)...
Abstract Introduction The 2010 cardiopulmonary resuscitation guidelines recommend emergency medical services (EMS) personnel consider prehospital termination-of-resuscitation (TOR) rules for out-of-hospital cardiac arrest (OHCA) following basic life support and/or advanced efforts in the field. However, rate of implementation international TOR is still low. Here, we aimed to develop and validate a new rule department physicians replace EMS This aims guide deciding whether withhold further...
To assess the efficacy of prophylactic administration anticoagulant and antiaggregant drugs to prevent venous thrombosis after long‐term transvenous permanent pacemaker implantation, venograms were performed in 100 consecutive patients at elective replacement pacemaker. Mean follow‐up period initial implantation was 6.0 years. The demonstrated normal 77 patients. remaining 23 showed stenosis 11 total obstruction 12 Twenty‐one these had collateral circulation. No difference found incidence...
Abstract Introduction Estimation of outcomes in patients after out-of-hospital cardiac arrest (OHCA) soon arrival at the hospital may help clinicians guide in-hospital strategies, particularly emergency department. This study aimed to develop a simple and generally applicable bedside model for predicting arrest. Methods We analyzed data 390,226 adult who had undergone OHCA, from prospectively recorded nationwide Utstein-style Japanese database 2005 through 2009. The primary end point was...
Abstract Introduction The prognostic significance of conversion from nonshockable to shockable rhythms in patients with initial who experience out-of-hospital cardiac arrest (OHCA) remains unclear. We hypothesized that the neurological outcomes those would improve subsequent shock delivery following and time initiation cardiopulmonary resuscitation by emergency medical services personnel first defibrillation (shock time) influence outcomes. Methods analyzed data 569,937 OHCA adults rhythms....
The appropriate duration of cardiopulmonary resuscitation (CPR) for pediatric out-of-hospital cardiac arrests (OHCAs) remains unclear and may differ based on initial rhythm. We aimed to determine the relationship between prehospital CPR by emergency medical services (EMS) personnel post-OHCA outcomes.We analyzed records 12 877 patients who experienced OHCAs (<18 years age). Data were recorded in a nationwide Japanese database 2005 2012. Study end points 30-day survival with favorable...
Abstract Inflammation and glycemic control are important prognosis‐related factors for hemodialysis ( HD ) patients; moreover, inflammation affects insulin secretion. Here, we evaluated the anti‐inflammatory effects of monotherapy with linagliptin—a dipeptidase‐4 inhibitor—in patients type 2 diabetes. We examined 21 diabetic who were not receiving oral diabetes drugs or therapy poor (glycated albumin [ GA ] level, >20%). Linagliptin (5 mg) was administered to daily. The levels...
Background The response time of emergency medical services ( EMS ) is an important determinant survival after out‐of‐hospital cardiac arrest. We sought to identify upper limits times and bystander interventions associated with neurologically intact survival. Methods Results analyzed the records 553 426 patients arrest in a Japanese registry between 2010 2014. primary study end point was 1‐month (Cerebral Performance Category scale 1 or 2). Increased significantly decreased adjusted odds...
As emergency medical services (EMS) personnel in Japan are not allowed to perform termination of resuscitation the field, most patients experiencing an out-of-hospital cardiac arrest (OHCA) transported hospitals without a prehospital return spontaneous circulation (ROSC). crucial factors for outcomes clear who had OHCA ROSC, we aimed determine associated with 1-month favorable neurological (Cerebral Performance Category scale 1 or 2 (CPC 1-2)).We analyzed data 398,121 adult ROSC from...
At hospital arrival, early prognostication for children after out-of-hospital cardiac arrest (OHCA) might help clinicians formulate strategies, particularly in the emergency department. In this study, we aimed to develop a simple and generally applicable bedside tool predicting outcomes arrest.We analyzed data of 5,379 who had undergone OHCA. The were extracted from prospectively recorded, nationwide, Utstein-style Japanese database. primary endpoint was survival with favorable neurological...
Background:There is sparse data regarding the survival and neurological outcome of elderly patients with out-of-hospital cardiac arrest (OHCA).Methods Results:OHCA (334,730) aged ≥75 years were analyzed using a nationwide, prospective, population-based Japanese OHCA database from 2008 to 2012. The overall 1-month favorable (Cerebral Performance Category Scale, category 1 or 2; CPC 1-2) rate was 0.88%. During study period, annual 1-2 in whole significantly improved (0.73% 0.96%, P for trend...
It remains unclear whether men have more favorable survival outcomes after out-of-hospital cardiac arrest (OHCA) than women. We reviewed a total of 386,535 patients aged ≥ 18 years with OHCA who were included in the Japanese registry from 2013 to 2016. The study endpoints rates 1-month and neurologically intact (Cerebral Performance Category Scale score = 1 or 2). Based on age, categorized into following eight groups: < 30, 30–39, 40–49, 50–59, 60–69, 70–79, 80–89, 90 years. women compared...
<b><i>Aim:</i></b> To evaluate the long-term efficacy of monotherapy with dipeptidase-4 inhibitor alogliptin benzoate in hemodialysis (HD) patients type 2 diabetes. <b><i>Methods:</i></b> Sixteen diabetic HD inadequate glycemic control (hemoglobin A<sub>1c</sub> (HbA1c) level >6.5% and glycated albumin (GA) >20%) on diet exercise participated study. No were taking other oral antidiabetic drugs or receiving insulin therapy....
Abstract Background In Japan, emergency medical service (EMS) providers are prohibited from field termination-of-resuscitation (TOR) in out-of-hospital cardiac arrest (OHCA) patients. 2013, we developed a TOR rule for department physicians (Goto’s rule) immediately after hospital arrival. However, this is subject to flaws, and there need revision owing its relatively low specificity predicting mortality compared with other rules the department. Therefore, study aimed develop validate...
We previously constructed a risk prediction model of vancomycin (VCM)-associated nephrotoxicity for use when performing initial therapeutic drug monitoring (TDM), using decision tree analysis. However, we could not build to be used at the time administration due insufficient sample size. Therefore, performed multicenter study four hospitals in Japan. investigated patients who received VCM intravenously standard dose from first day until TDM November 2011 March 2019. Acute kidney injury (AKI)...