A5071439919- Neuroscience and Neural Engineering
- Graphene and Nanomaterials Applications
- Force Microscopy Techniques and Applications
- 3D Printing in Biomedical Research
- Advanced Electron Microscopy Techniques and Applications
- Supercapacitor Materials and Fabrication
- Advanced Fluorescence Microscopy Techniques
- Graphene research and applications
- Silicon Nanostructures and Photoluminescence
- Advanced Materials and Mechanics
- Neural dynamics and brain function
- Advanced Sensor and Energy Harvesting Materials
- RNA Interference and Gene Delivery
- Electron and X-Ray Spectroscopy Techniques
- Electrochemical Analysis and Applications
- Plasmonic and Surface Plasmon Research
- EEG and Brain-Computer Interfaces
- Conducting polymers and applications
- Photonic and Optical Devices
- Electrospun Nanofibers in Biomedical Applications
- Nanopore and Nanochannel Transport Studies
- Nanowire Synthesis and Applications
- Photonic Crystals and Applications
NTT Basic Research Laboratories
2014-2025
NTT (Japan)
2003
Peripheral nerve stimulation using implantable electrodes has gained significant attention as a potential treatment for drug-resistant neurological disorders. Developing deformable thin-film electrode devices is essential to minimize damage when interfacing with fine fibers. Here, we demonstrate self-folding graphene-based peripheral stimulation. The films were patterned holes and slits control the folding direction, enabling thin film wrap around fibers while allowing current application...
Three-dimensional (3D) graphene architectures are of great interest as applications in flexible electronics and biointerfaces. In this study, we demonstrate the facile formation predetermined 3D polymeric microstructures simply by transferring monolayer graphene. The adheres to surface films via noncovalent π–π stacking bonding induces a sloped internal strain, leading self-rolling microscale architectures. Micropatterns varied thicknesses 2D prior allows for control over resulting...
Abstract Electrophysiology of 3D neuronal cultures is rapidly growing importance for revealing cellular communications associated with neurodevelopment and neurological diseases in their brain‐like environment. Despite that the brain also exhibits an inherent modular architecture essential cortical processing, it remains challenging to interface a network consisting multiple tissues. Here, self‐folding graphene‐based electrode array proposed enables reconstruct tissue investigate firing...
We co-cultured endothelial and smooth muscle cells in a self-folding porous film to create vessel-like vitro model. The tunability of the geometries including curvature pore size enables us emulate small artery.
Three-dimensional (3D) architectures of graphene are great interest for applications in flexible electronics, supercapacitors, and biointerfaces. Here, we demonstrate that multi-layer (MLG), like single-layer (SLG), can self-fold to form 3D at the interface with a polymeric film. Bilayers composed film tightly adhere each other possess sloped internal strain, which leads spontaneous rolling predetermined microscale architectures. The curvature radii self-folding films be controlled by...
Interfaces between single neurons and conductive substrates were investigated using focused ion beam (FIB) milling subsequent scanning electron microscopy (SEM) observation. The interfaces play an important role in controlling neuronal growth when we fabricate neuron-nanostructure integrated devices. Cross sectional images of cultivated obtained with FIB/SEM dual system show the clear affinity for substrates. Very few attached themselves to indium tin oxide (ITO) this repulsion yielded a...
Neuronal patterning is useful for understanding signal propagation between neurons as well biosensors and cell-based assays. The of living cells has been made possible by employing surface physicochemical topographic features. This study investigated neuronal growth on patterned nanopillars. Rat cortical were cultivated quartz substrates with amorphous silicon (a-Si) Au pillars 100 500 nm in diameter. neurites grew better the larger diameter pillars, partly-selective neurite was observed...
Neuronal guidance on a device is key issue to achieve artificial synapses towards the goal of developing post-synaptic structures.NTT Basic Research Laboratories has established method for examining in vitro affinity neurons substrate by observing detail interface between neuron and surface using focused ion beam/scanning electron microscope at single level.With this knowledge hand, we fabricated nanostructures materials with high examined ability control neuronal growth structure.We...
We propose a hydrophilic-raised-ring structure at the aperture of hole for efficient suspension lipid bilayer. This ring can be fabricated by using combination consisting focused ion beam (FIB) and hydrogen silsesquioxane (HSQ) negative electron (EB) resist layer on substrate. Negative EB selectively reacted with scattered gallium during FIB milling process, obtained employing development process. Assessments cross section revealed two-step structure. The bilayers structures was assessed...
Neural Interfaces In article number 2301836, Koji Sakai and co-workers show that the self-folding graphene-based electrode array can record neuronal activities from multiple 3D aggregates interconnected to form a brain-like modular culture. This brain-on-a-chip technology will help understand electrophysiological behavior of neurons in complex networks.
Surface-plasmon polaritons (SPPs) act as extraordinary electromagnetic waves having spatially squeezed field intensity distributions, that couple with oscillation of dense conductive matter and propagate at a metal-dielectric interface. Plasmon-mode metal waveguides are the channels to support their propagation. Characterization based on Maxwell equations gives clear understanding plasmon mode in terms propagation properties, such dispersion relations. The method is extended analysis slab...