Aim of the Study: The aim this study is to evaluate demographic and clinicopathological profile patients with gallbladder cancer (GBC). Materials Methods: A total 68 diagnosed cases GBC were taken in during period from January 2016 December 2017. detail questionnaire was filled through counseling take including socioeconomic status, nonclinical characteristics, dietary, other risk factors apart patients. Results: We found most females median age 51.8 years. More than half them postmenopausal...

Around 80% of colorectal carcinoma are associated with chromosomal instability (CIN) while rest 20 % euploid, possessing defect in mis match repair system (MMR) quintessential for surveillance and correction errors introduced into microsatellites.We analyse all stage II CRC MSI who presented at MDTC Army hospital (research refrral) new delhi during last 2 years (Jan 14 to Dec 2015).We found that 22.2% patients out 45 stageII being MSI-. high. We also noticed suchcases were loss expression...

Lung cancer is the most common malignant disease and topmost cause of deaths in world across all age groups both sexes. It developed countries also rising at an alarming rate developing countries.The present study was undertaken to explore clinicopathological molecular profile bronchogenic carcinoma northwestern population India.A total 136 consecutive patients with histologically proven carcinoma, registered between May 2014 April 2016 a tertiary care hospital New Delhi, India, were...

Background: The bedside index for severity in acute pancreatitis (BISAP), a newer prognostic scoring system, has been proposed as simple and clinically oriented system early identification of patients with pancreatitis. This study evaluates the efficacy BISAP score to predict organ failure pancretitis its correlation Marshall score.Methods: clinical, laboratory radiological data all admitted diagnosis conducted at tertiary hospital Armed Forces over two-year period, was prospectively...

Diffuse large B cell lymphoma (DLBCL) is the most common histologic subtype of non-Hodgkin (NHL) accounting for approximately 30 percent all NHL cases, involving both nodal and extra-nodal sites. Apart from distinct morphological clinicopathological subtypes, DLBCL can be dived into molecular Germimal Centre Subtype (GCB) Activated B-Cell (ABC) based on gene expression profiling. IPI (International Prognostication Index) its variants are used to prognosticate patients. Limited stage...

A novel fusion gene of echinoderm microtubule-associated protein-like 4 (EML4) and anaplastic lymphoma kinase (ALK) has been identified in a subset non-small-cell lung cancers (NSCLCs). Patients with the ALK-EML4 demonstrate unique clinicopathological physiological characteristics. Here we present an analysis profile patients metastatic adenocarcinoma harboring their response to targeted therapy form crizotinib.A retrospective advanced ALK positive NSCLC, who presented at this tertiary care...

The Journal of Cancer Metastasis and Treatment is an open access journal focused on cancer metastasis treatment, including the occurrence, development, progression, metastasis, treatment oncologic disease. It covers basic, translational clinical research related to cell biology, genomics, precision medicine, oncology internal radiotherapy radiology, obstetrics gynecology, pediatrics, surgery, hematology, neurooncology, etc.

Abstract Background: Digital papillary adenocarcinoma (DPA) is a very rare malignant tumor of the sweat glands originally described by Helwig in 1979.It often presents as solitary painless mass, commonly found on volar surface fingers and toes adjacent skin palms soles. Materials Methods: Two cases DPA 43- 48-year-old male patients who presented with swelling finger were included over period one year study tertiary care hospital. Results: Our had two patient age 48 43 old. Both mass lesion...

Background: Breast cancer is the most common affecting women all over world. In India, it second solid-organ malignancy after carcinoma cervix. Worldwide, approximately 5%–10% of cases have been associated with various germline mutations. However, in studies correlating BRCA mutation clinicopathological variables are rare. this study, we tried to find out difference BRCA-mutated and BRCA-nonmutated patients. Materials Methods: From May 2015 2017, 50 patients breast were subjected mutational...

Background: Lorlatinib, an anaplastic lymphoma kinase (ALK)-inhibitor, is approved as frontline well subsequent line of therapy in ALK-rearranged advanced non-small cell lung cancer (NSCLC).There limited literature about safety and efficacy lorlatinib Indian patients. Materials methods:This was a retrospective multicentre study on patients with ALKrearranged NSCLC received second beyond between May 2017 December 2021.ALK tested either by immunohistochemistry or fluorescent in-situ...

Background: Non Hodgkins lymphoma is the most prevalent hematopoietic neoplasm, representing approximately 4% of all cancer diagnoses and ranking seventh in frequency among cancers. Most data that we have west pertaining to Indian subcontinent lacking. The aim this study was clinical profile, prognostication, assess treatment outcome DLBCL patients a tertiary care hospital.Methods: 100 reporting hospital between 2013 2016 were chosen for study. All subjected routine investigation specialized...

Although tobacco use is declining in several countries including India (dropping from 35% 2009-10 to 29% 2016-17 among adults)-it still poses a huge burden on India, as the world's second largest consumer of products. In Bihar state, with prevalence 25%, School Teachers Study (BSTS) successfully enlisted teachers role models for encouraging quitting and changing social norms pertaining tobacco. The study used mixed-methods approach identify factors associated teachers' quitting. Qualitative...

Metastatic gallbladder cancer (GBC) is a highly fatal malignancy and it difficult to treat the advanced stage of GBC. In India, northern northeastern states are worst affected by this disease. We, hereby, report clinicoepidemiological management profile 242 patients metastatic carcinoma GB.In study, total cases GBC (detected either on first presentation or during follow-up) were managed at Department Medical Oncology tertiary care oncology center in northeast part India from May 2018...

Introduction: Lymphoma is a neoplastic proliferation of lymphoid cells at various stages differentiation and affects lymph nodes, with infiltration into the bone marrow, spleen, thymus, which form primary lymphatic organs. Extranodal lymphoma, by definition, involves sites other than pharyngeal ring. involvement less common Hodgkin lymphoma (HL) non-Hodgkin (NHL). Materials Methods: A single-center retrospective observational study was conducted over period 2017–2019. Age, gender, histologic...

Abstract Objective Indian data on cancer patients with coronavirus disease 2019 (COVID-19) infection and its outcome are limited. Infectivity among staying in large congregations not known. We conducted this study to address lacuna literature. Methods This was a retrospective–prospective, observational of hospitalized proven COVID-19 infection, at tertiary care hospital New Delhi after ethical approval. analyzed clinical, laboratorial parameters, outcomes these patients. Results All 32...

Abstract Introduction There is a lacuna of prospective studies on soft tissue sarcoma (STS) from the Indian subcontinent in published literature. Objectives We conducted this study to describe clinical profile and outcomes STS North India. Materials Methods This single-center, prospective, observational October 2017 September 2019. All consecutive patients aged ≥18 years with histopathological diagnosis were enrolled. The end points included overall response rate, progression-free survival...