A5101570814- Ovarian cancer diagnosis and treatment
- Lung Cancer Research Studies
- Lung Cancer Treatments and Mutations
- Gastric Cancer Management and Outcomes
- Cancer Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Testicular diseases and treatments
- PARP inhibition in cancer therapy
- Cancer Genomics and Diagnostics
- COVID-19 and healthcare impacts
- Endometrial and Cervical Cancer Treatments
- Breast Cancer Treatment Studies
- Metastasis and carcinoma case studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal Cancer Treatments and Studies
- Sarcoma Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Renal cell carcinoma treatment
- Brain Metastases and Treatment
- Cancer Treatment and Pharmacology
- HER2/EGFR in Cancer Research
- Pancreatic and Hepatic Oncology Research
- Advanced Breast Cancer Therapies
- Neuroendocrine Tumor Research Advances
- COVID-19 Clinical Research Studies
Tata Medical Center
2017-2024
Yashoda Hospital
2024
India Diabetes Research Foundation
2023
Creative Commons
2023
Tata Memorial Hospital
2013-2022
Medanta The Medicity
2022
Homi Bhabha National Institute
2022
Raiganj University
2021
Advanced Centre for Treatment, Research and Education in Cancer
2017-2021
National University of Singapore
2020
The coronavirus disease 2019 (COVID-19) pandemic has imposed a unique challenge to oncology patients and their treatment. There is no study related the patients' preference for systemic therapy during this pandemic. We have conducted prospective analyze that aspect.All consecutive who visited lockdown period from April 1-10, 2020, chemotherapy were included in questionnaire-based survey evaluate willingness continue factors influencing decisions.A total of 302 (median age, 56 years; range,...
Purvish M ParikhS-1 (5-fluorouracil prodrug [tegafur] in combination with 5-chloro-2,4-dihydroxypyridine [CDHP] and potassium oxonate [OXO]) was first approved 1999. In order to make it easy for community oncologists, we decided put together this expert consensus guideline its use gastrointestinal (GI) malignancies. A total of 15 subject matter experts used modified Delphi method discuss, analyze, vote on key aspects regarding practical approach S-1 GI cancers, a process involving 6 months...
Multimodality treatment of gastrointestinal stromal tumor (GIST) with surgery and adjuvant imatinib mesylate (IM), along an emerging role for neoadjuvant IM prior to evaluation resectability has resulted in high survival rates.We conducted a retrospective analysis prospectively collected data patients who underwent GIST, or followed by therapy. A total 112 between January 2009 March 2015 at our centre. This included 27 upfront resectable disease, 76 locally advanced GIST received 9...
Triple-negative breast cancer (TNBC) has a poor outcome compared to other subtypes, even in those with early disease. Immune checkpoint inhibitors (ICIs) have been approved metastatic diseases and are being tested as neoadjuvant strategy also. The response ICIs is largely determined by the programmed death ligand 1 (PDL1) score, which also acts prognostic marker for outcomes. Here, we report proportion of PDL1 expression non-metastatic TNBC its correlation chemotherapy outcomes.We included...
Left main coronary artery disease carries a poor prognosis. The etiology of isolated and significant left (ILMCA) is not well understood. Studies so far were limited by small numbers. authors identified 46 patients with ILMCA from their database over 10 years (group I) compared them 83 consecutive undergoing catheterization II). They also ostial vs distal disease. Group I represented 0.1% patients. demographic profile atherosclerotic risk factor the 2 groups as compared. This largest study...
Many agents have shown survival advantage in metastatic castrate-resistant prostate cancer (mCRPC). Despite this improvement, is poor, especially subgroup of elderly patients who are not fit for cytotoxic chemotherapy.This a single-institutional data review mCRPC treated between December 2012 and May 2016 with oral cyclophosphamide (50-100 mg/day) ± prednisolone. mCRPCs failed or docetaxel and/or abiraterone were included study. Monthly prostate-specific antigen (PSA) was monitored, toxicity...
Data on epidemiology and outcome in metastatic stomach carcinoma patients from India are scarce. We aimed to evaluate clinical features treatment treated at our center.This is a single institutional review of gastric between May 2011 October 2016. Patients who received least one cycle chemotherapy were included for modified intent-to-treat survival analysis.total 143 diagnosed with median age 56 years (range: 29-86). The most common symptoms abdominal pain 112 (78%) patients. site was body...
e13128 Background: Contrary to earlier published data using manual IHC methods, we had reported Triple negative breast cancer (TNBC) rates of 11-15% as in western literature. Here report the demographic characteristics, failure patterns, and survival outcomes follow up. Methods: All TNBC patients were identified from a cohort 2367 non metastatic between 2011 - 2017. Demographic clinical information collected. Patterns recurrence documented simple statistical methods used frequencies...
Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors have shown marked benefit in the treatment of hormone positive metastatic breast cancer (HR+ MBC). There are limited real-world studies with palbociclib and ribociclib. Here we report our experience CDK4/6 these groups patients.Patients HR+ MBC who received either or ribociclib during course their from January 2017 to 2022 were included study. The baseline demographic features, details toxicity recorded. Patients at least 1 month therapy...
Background: Treatment of the Covid-19 pandemic caused by highly contagious and pathogenic SARS-CoV-2 is a global menace. Day day, this getting worse. Doctors, scientists researchers across world are urgently scrambling for cure novel corona virus continuously working at break neck speed to develop vaccines or drugs. But date, there no specific drugs available in market cope up with virus. Objective: The present study helps us elucidate 3D structures proteins also identify natural compounds...
Abstract Background Malignant mediastinal germ cell tumor (MGCT) is rare and has poor outcomes even after multimodality treatment. Data from resource‐poor countries are scarce in the literature. Aims To evaluate clinicopathologic features treatment outcome of primary malignant MGCT at our center. Methods Results Single institutional data review patients aged ≥18 years, treated with a diagnosis between Nov'2013 Nov'2019. Risk stratification was done as per International Germ Cell Cancer...
The coronavirus disease 2019 (COVID-19) pandemic has caused a significant disruption and delay in the delivery of health-care services globally. Moreover, there have been reports increased morbidity mortality patients with cancer.[1234] Multiple hospitals India across world were designated as COVID-19 care centers, thus affecting routine clinical practice.[5] Besides this, workers started getting infected severe acute respiratory syndrome 2, mandating quarantine for 2–3 weeks, further...
Abstract Introduction Breast cancer is the most frequent among women. In last few decades, outcome of breast has improved significantly in terms survivorship and quality life. However, it crucial that alongside managing disease, services address manage associated or co-occurring psychiatric illnesses such as acute stress reactions, procedural anxieties, adjustment issues, depression, fear recurrence, which leads to an overall better experience patient. Objective There a paucity data on...
Pathological complete response (pCR) in breast cancer is traditionally defined (as per the United States Food and Drug Administration [USFDA]) as absence of residual invasive on histopathologic hematoxylin eosin evaluation resected specimen all sampled regional lymph nodes following completion neoadjuvant systemic therapy.[1] Achievement pCR one most common primary endpoints for clinical trials setting. The surrogate predictive value event-free survival (EFS) overall (OS) has been...