Chandan Krushna Das

ORCID: 0000-0003-2159-8227
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About
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Research Areas
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Prostate Cancer Treatment and Research
  • Gallbladder and Bile Duct Disorders
  • Lung Cancer Research Studies
  • COVID-19 and healthcare impacts
  • Neuroendocrine Tumor Research Advances
  • Radiopharmaceutical Chemistry and Applications
  • Cancer Immunotherapy and Biomarkers
  • Ovarian cancer diagnosis and treatment
  • Neuroblastoma Research and Treatments
  • Economic and Financial Impacts of Cancer
  • Radiomics and Machine Learning in Medical Imaging
  • Sarcoma Diagnosis and Treatment
  • Intraperitoneal and Appendiceal Malignancies
  • Cancer Diagnosis and Treatment
  • Renal cell carcinoma treatment
  • Lymphoma Diagnosis and Treatment
  • Testicular diseases and treatments
  • Vascular Tumors and Angiosarcomas
  • Chronic Lymphocytic Leukemia Research
  • Inflammatory Biomarkers in Disease Prognosis
  • PARP inhibition in cancer therapy
  • Prostate Cancer Diagnosis and Treatment
  • Viral-associated cancers and disorders
  • Cancer Treatment and Pharmacology

Post Graduate Institute of Medical Education and Research
2004-2025

Montefiore Medical Center
2025

Icahn School of Medicine at Mount Sinai
2023-2024

University of Pennsylvania
2022-2023

Indian Institute of Technology Kharagpur
2023

All India Institute of Medical Sciences
2002-2022

Institute of Medical Sciences
2022

Army Hospital Research and Referral
2021

Regional Cancer Center
2020

Rajshahi Medical College
2016-2018

<sup>177</sup>Lu-DOTATATE has emerged as a viable treatment strategy for advanced well-differentiated grade 1/2 gastroenteropancreatic neuroendocrine tumors (GEP-NETs). Few retrospective studies have shown concomitant with radiosensitizing low-dose capecitabine to be effective in NETs. However, this not been validated prospective randomized-controlled trials. <b>Methods:</b> In investigator-initiated, parallel-group, open-label, phase 2 trial, patients GEP-NETs, having progressive...

10.2967/jnumed.124.268617 article EN Journal of Nuclear Medicine 2025-01-08

Gallbladder cancer (GBC) is highly aggressive. Diagnosis of GBC challenging as benign gallbladder lesions can have similar imaging features. We aim to develop and validate a deep learning (DL) model for the automatic detection at abdominal ultrasound (US) compare its diagnostic performance with that radiologists. In this prospective study, multiscale, second-order pooling-based DL classifier was trained (training validation cohorts) using US data patients acquired between August 2019 June...

10.1016/j.lansea.2023.100279 article EN cc-by-nc-nd The Lancet Regional Health - Southeast Asia 2023-09-11

<h3>BACKGROUND</h3> The prevalence of childhood asthma is increasing but few studies have investigated trends in severity. We diagnosis and symptom morbidity between an eight year time period a paired study. <h3>METHODS</h3> All children one single school aged 8–9 years the city Sheffield were given parent respondent questionnaire 1991 1999 based on questions from International Survey Asthma Allergy Children (ISAAC). Data obtained regarding wheeze current (12 month) prevalences attacks,...

10.1136/thorax.56.4.312 article EN Thorax 2001-04-01
Gustavo H. Dayan Nadine Rouphael Stephen R. Walsh Aiying Chen Nicole Grunenberg and 95 more Mary Allen Johannes Antony Kwaku Poku Asante Amit Bhate Tatiana Beresnev Matthew Bonaparte Médéric Celle Maria Angeles Ceregido Lawrence Corey D.V. Dobrianskyi Bo Fu Marie-Hélène Grillet Maryam Keshtkar‐Jahromi Michal Juraska Jia Jin Kee Hannah Kibuuka Marguerite Koutsoukos Roger Masotti Nelson L. Michael Kathleen M. Neuzil Humberto Reynales Merlin L. Robb Sandra M. Villagómez Martínez Fredrick Sawe Lode Schuerman Tina Tong John J. Treanor T. Anh Wartel Carlos A. DiazGranados Roman M. Chicz Sanjay Gurunathan Stephen J. Savarino Saranya Sridhar Karina Abalos José Accini Naveena Aloysia John Amuasi Nana Akosua Ansah David Benkeser Aude Berge Hanna Beyko Oleksandra Bilotkach Thomas Breuer Alberto Cadena Elisabeth Bukusi Richard Canter J. Carrillo Danaya Chansinghakul Florence Coux Chandan Krushna Das Santa Kumar Das Louis Devlin Luis Espinoza Michael P. Fay Dean Follmann Carina Frago Agnes Garinga Peter B. Gilbert Claudia González Maria Angelica Granados Lea Guillery Ying Huang Kathy Hudzina Manish Kumar Jain Piush Kanodia Nitin Khandelwal Cissy Kityo Francis Kiweewa Noah Kiwanuka Chalit Kosolsak Darshna Kukian Jitendra Singh Kushwaha Thelma Laot Eduardo López-Medina Hugo Macareno Arroyo Kishorchandra Mandaliya Stephanie Mamod Somnath Mangarule Javier Martínez Scott McClelland Lisa Menard Sandra Mendoza Satyajit Mohapatra Catherine Moreau Nelly Mugo Videlis Nduba Fernando Noriega Patricia Nahirya Ntege Brenda Okech María Calado Otero Samuel Gurrion Ouma Janet Oyieko Mercedes Paredes Erwin Pardo Svitlana Postol

10.1016/s2213-2600(23)00263-1 article EN publisher-specific-oa The Lancet Respiratory Medicine 2023-09-13

168 Background: Docetaxel combined with prednisone is the first line chemotherapy to improve overall survival in metastatic castration resistant prostate cancer (mCRPC). Nanosomal docetaxel lipid suspension (NDLS) a novel formulation that eliminates need for polysorbate 80 and ethanol, reducing infusion-related reactions requirement steroid premedication. This phase 4 trial aims assess efficacy safety of NDLS patients mCRPC. Methods: In this multicenter, open-label, single-arm trial,...

10.1200/jco.2025.43.5_suppl.168 article EN Journal of Clinical Oncology 2025-02-10

PURPOSE It is projected that approximately 50,000 new cases of prostate cancer will be diagnosed in 2020 India. Survival has improved because the development effective drugs such as abiraterone acetate, but universal accessibility to treatment not always possible cost constraints lower- and middle-income countries. Recently, National Comprehensive Cancer Network (NCCN) included low-dose (250 mg/day) with food an alternative option full-dose (1,000 fasting. METHODS The Science Cost Consortium...

10.1200/jgo.19.00341 article EN cc-by-nc-nd JCO Global Oncology 2020-03-03

Actinium-225 (225Ac) labeled prostate-specific membrane antigen (PSMA)-617 is a novel treatment modality in the management of metastatic castration-resistant prostate cancer (mCRPC). The present study was conducted to assess impact 225Ac-PSMA-617 therapy on quality-of-life patients with heavily pretreated mCRPC using National Comprehensive Cancer Network-Functional Assessment Therapy-Prostate Symptom Index-17 (NCCN-FACT-FPSI-17) questionnaire.This retrospective single-center where data...

10.4103/ijnm.ijnm_130_20 article EN Indian Journal of Nuclear Medicine 2020-01-01

The prostate-specific membrane antigen (PSMA) inhibitor [<sup>177</sup>Lu]Lu-PSMA-617 has been previously demonstrated to be noninferior docetaxel in achieving a biochemical response chemotherapy-naïve metastatic castration-resistant prostate cancer patients. Here, we report the final analysis of overall survival (OS) for phase 2 randomized, controlled trial. <b>Methods:</b> Forty chemotherapy-naïve, PSMA-positive patients were randomly assigned (<i>n</i> = 20) or 20). Thirty-five received...

10.2967/jnumed.123.266141 article EN Journal of Nuclear Medicine 2023-09-14

Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin's lymphoma. We conducted a retrospective study to analyze clinicopathological characteristics, cell origin, response therapy, and outcome patients with DLBCL.This was which included all DLBCL registered at our center, between May 1, 2013, July 31, 2015. The data regarding demography, clinical presentation, histopathology, stage, prognostic index, treatment, treatment-related were collected from prospectively...

10.4103/sajc.sajc_65_18 article EN cc-by-nc-nd South Asian Journal of Cancer 2018-07-01

Abstract Gall bladder cancer (GBC) is common among the socioeconomically deprived populations of certain geographical regions. Aflatoxin a genotoxic hepatocarcinogen, which recognized to have role in pathogenesis hepatocellular carcinoma. However, aflatoxin GBC largely unknown. We determined serum AFB1‐Lys albumin adduct (AAA) levels as marker exposure patients with and compared those without GBC. The relationship AAA cytogenetic (TP53mutation&amp;HER2/neu amplification) radiological...

10.1002/ijc.35171 article EN International Journal of Cancer 2024-09-06

This cross-sectional type of descriptive study was conducted in three villages Puthia Upazila under Rajshahi district to find out the prevalence Generalized Anxiety Disorder (GAD) and its effect on their daily living. A total 876 adult people aged 18 years above, were selected purposively. Data collected by face interview with help a semi-structured questionnaire which contained Hamilton’s 7-point anxiety scale. Out respondents, 80% had GAD, where mild, moderate severe GAD being 42.5%, 31.8%...

10.3329/taj.v27i1.37603 article EN TAJ Journal of Teachers Association 2018-11-28

PSMA-based radioligand therapies have shown the beneficial effect in metastatic castrate-resistant prostate cancer (mCRPC) patients when they become refectory to established treatments with associated potential toxicities and high mortality rate. Ac-PSMA therapy is known be remarkably effective substantially pretreated mCRPC patients. However, posttherapy imaging usually not performed as alpha emitters are really difficult image. We presents a patient of treated Ac-PSMA-617, his whole-body...

10.1097/rlu.0000000000003031 article EN Clinical Nuclear Medicine 2020-05-04
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