A5071268553- Prostate Cancer Treatment and Research
- Renal cell carcinoma treatment
- Prostate Cancer Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Renal and related cancers
- Bladder and Urothelial Cancer Treatments
- Urologic and reproductive health conditions
- Renal and Vascular Pathologies
- Cancer Genomics and Diagnostics
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Cancer Cells and Metastasis
- Pediatric Urology and Nephrology Studies
- Urological Disorders and Treatments
- Cancer, Lipids, and Metabolism
- Genital Health and Disease
- Advanced Radiotherapy Techniques
- BRCA gene mutations in cancer
- Multiple and Secondary Primary Cancers
- Urinary and Genital Oncology Studies
- Pancreatic and Hepatic Oncology Research
- Cancer Immunotherapy and Biomarkers
- Peptidase Inhibition and Analysis
- Orthopaedic implants and arthroplasty
Icahn School of Medicine at Mount Sinai
2022-2025
Johns Hopkins Medicine
2015-2024
Johns Hopkins University
2015-2024
John Wiley & Sons (United States)
2018-2023
Urological Society of Australia and New Zealand
2020-2023
Mount Sinai Hospital
2023
Oxfam
2023
Liechtenstein Institute
2023
Western Maryland Health System
2020-2022
Urology Associates
2020-2022
Complete metastatic ablation of oligometastatic prostate cancer may provide an alternative to early initiation androgen deprivation therapy (ADT).To determine if stereotactic ablative radiotherapy (SABR) improves oncologic outcomes in men with cancer.The Observation vs Stereotactic Ablative Radiation for Oligometastatic Prostate Cancer (ORIOLE) phase 2 randomized study accrued participants from 3 US radiation treatment facilities affiliated a university hospital May 2016 March 2018 data...
Recent genomic studies challenge the conventional model that each metastasis must arise from a single tumor cell and instead reveal metastases can be composed of multiple genetically distinct clones. These intriguing observations raise question: How do polyclonal emerge primary tumor? In this study, we used multicolor lineage tracing to demonstrate seeding by clusters is frequent mechanism in common mouse breast cancer, accounting for >90% metastases. We directly observed multicolored across...
Current FDA-approved imaging modalities are inadequate for localizing prostate cancer biochemical recurrence (BCR).
Prostate specific membrane antigen-targeted positron emission tomography/computerized tomography has the potential to improve detection and localization of prostate cancer. OSPREY was a prospective trial designed determine diagnostic performance 18F-DCFPyL-positron for detecting sites metastatic cancer.Two patient populations underwent tomography. Cohort A enrolled men with high-risk cancer undergoing radical prostatectomy pelvic lymphadenectomy. B patients suspected recurrent/metastatic on...
Abstract Germ line mutations of the BRCA1 gene confer a high risk breast cancer and ovarian to female mutation carriers. The protein is involved in regulation DNA repair. How specific tumor-associated affect molecular function BRCA1, however, awaits further elucidation. Cell lines that harbor are invaluable tools for such functional studies. Up now, HCC1937 cell was only human with an identified mutation. In this study, we three other mutants from among 41 by sequencing complete coding...
See an invited perspective on this article page [466][1]. As medical imaging has grown progressively more complicated and subspecialized in recent decades, several standardized reporting systems have been proposed for a variety of modalities conditions. These include
Expanding indications for robot-assisted partial nephrectomy raise major oncologic concerns positive surgical margins. Previous reports showed no correlation between margins and outcomes. We report a multi-institutional experience with the outcomes of on nephrectomy.Pathological clinical followup data were reviewed from an institutional review board approved, prospectively maintained joint database 5 institutions. Tumors malignant pathology isolated statistically analyzed demographics...
Understanding the degree of phenotypic heterogeneity in a small renal mass may have implications for interpreting biopsy data. In this study we quantify nuclear grade masses.Our institutional database was queried patients with T1a (less than 4 cm) masses stratified by criteria imaging diameter less 2 cm or greater, clear cell papillary histology, low (Fuhrman 1-2) high 3-4) tissue available review. Four consecutive specimens were chosen from each 8 strata total 32. All reanalyzed and highest...
No AccessJournal of UrologyInvestigative Urology1 Nov 2013Outcomes and Predictors Clinical T1 to Pathological T3a Tumor Up-Staging after Robotic Partial Nephrectomy: A Multi-Institutional Analysis Michael A. Gorin, Mark W. Ball, Phillip M. Pierorazio, Youssef S. Tanagho, Sam B. Bhayani, Jihad H. Kaouk, Craig G. Rogers, D. Stifelman, Ali Khalifeh, Ramesh Kumar, Ganesh Sivarajan, Mohamad E. Allaf GorinMichael Gorin The James Buchanan Brady Urological Institute Department Urology, Johns Hopkins...