- Inhalation and Respiratory Drug Delivery
- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Airway Management and Intubation Techniques
- Asthma and respiratory diseases
- Infection Control and Ventilation
- Cystic Fibrosis Research Advances
- Innovations in Medical Education
- Nursing education and management
- COVID-19 and Mental Health
- Tracheal and airway disorders
- Medical Education and Admissions
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Healthcare professionals’ stress and burnout
- Pharmaceutical studies and practices
- Diversity and Career in Medicine
- Respiratory and Cough-Related Research
- Health and Well-being Studies
- Aerosol Filtration and Electrostatic Precipitation
- Artificial Intelligence in Healthcare and Education
- Intravenous Infusion Technology and Safety
- Nosocomial Infections in ICU
- COVID-19 and healthcare impacts
- Child and Adolescent Health
- COVID-19 diagnosis using AI
Texas State University
2017-2025
Georgia State University
2009-2022
Baptist Medical Center Jacksonville
2022
Akdeniz University
2017
Creative Research Enterprises (United States)
2016
For over a century, nebulizers have been commonly used to deliver aerosolized medications in the treatment of patients with pulmonary diseases.They are aerosol device choice when can not coordinate inhalation and actuation needed for use pressurized metered-dose inhalers (pMDIs) or able provide necessary inspiratory flow required by dry powder inhaler (DPI) effective drug delivery.Three types exist: (1) jet nebulizers, (2) ultrasonic (3) mesh nebulizers.The purpose this paper is explain...
Abstract Drug administration via high flow nasal cannula (HFNC) has been described in pediatrics but the amount of albuterol delivery with an HFNC is not known. The purpose this study to quantify aerosol heliox and oxygen (O 2 ) a model pediatric ventilation. A vibrating mesh nebulizer (Aeroneb Solo, Aerogen) was placed on inspiratory inlet heated humidifier wire circuit attached (Optiflow, Fisher & Paykel). Breathing parameters were tidal volume (V t 100 ml, respiratory rate (RR)...
Different types of nebulizers and interfaces are used for the treatment adults children with pulmonary diseases. The purpose this study was to determine efficiency a mesh nebulizer (MN) proprietary adapter jet (JN) under different configurations in adult pediatric models spontaneous breathing. We hypothesize that delivery JN MN will differ depending on interface during aerosol therapy simulated spontaneously breathing models. While we expect be less efficient than MN, also lung deposition...
Using an electronic literature search for published articles indexed in PubMed between January 1990 and August 2011, the update of this clinical practice guideline is result reviewing 84 trials, 54 reviews, 25 vitro studies, 7 evidence-based guidelines. The recommendations below are made following Grading Recommendations Assessment, Development, Evaluation (GRADE) criteria: 1: It recommended that selection appropriate aerosol generator interface be based on patient9s age, physical cognitive...
Background: Concerns have been expressed about risk of exposure to exhaled aerosols ICU personnel.AIM: To quantify amount aerosol collected at the exhaust outlet mechanical ventilators operated with and without filters in expiratory limb.Methods: Two categories were tested: (1) Ventilators Proprietary Filters: Servo-i (Maquet) Galileo (Hamilton) (2) Ventilator proprietary filters: PB 840 (Covidien).Each ventilator was attached a simple test lung VT 500 ml, RR 20 bpm, PIF 50 L/min, PEEP 5...
Aerosol drug delivery via high flow nasal cannula (HFNC), bubble continuous positive airway pressure (CPAP), and synchronized inspiratory (SiPAP) has not been quantified in spontaneously breathing premature infants.The purpose of this study was to compare aerosol HFNC, CPAP, SiPAP a model simulated preterm infant.The types CPAP systems nebulizer positions used during therapy will impact deposition infants.Quantitative, comparative, in-vitro study.A breath simulator set infant settings (VT :...
<h3>BACKGROUND:</h3> Heliox (helium-oxygen mixture) has been shown to reduce turbulence and improve aerosol delivery in a range of clinical settings. We questioned whether heliox as compared with oxygen via high-flow nasal cannula (HFNC) would affect delivery. hypothesized that have significant effect on both quiet distressed breathing patterns. <h3>METHODS:</h3> A vibrating mesh nebulizer was placed at the inlet humidifier HFNC small adult distal heated-wire circuit prongs into simulated...
Background: Inhaled medications form the foundation of pharmacologic treatment for chronic obstructive pulmonary disease (COPD).The Delivery Makes a Difference (DMaD) project was conducted to better understand health care provider (HCP) and patient perspectives about role inhalation delivery devices in COPD, examine nature educational efforts between HCPs patients on proper device technique. Methods: Data were derived from 2 original quantitative, web-based, descriptive, cross-sectional...
Abstract Objectives Trans‐nasal pulmonary aerosol delivery for infants and toddlers has recently gained popularity, however, the reported lung deposition is low. We aimed to investigate influential factors improve delivery. Methods Anatomic airway manikins simulating infant (5 kg) toddler (15 with collecting filter connected trachea breath simulator, were set represent quiet distressed breathing. Nasal cannula flow was at 0.125, 0.25, 0.5, 1, 2 L/kg/min. A mesh nebulizer (Aerogen) placed...
Background: Trans-nasal pulmonary aerosol delivery using high flow nasal cannula (HFNC) devices is described with the administration of gas flows exceeding patient inspiratory (HF) and lower (LF). The aim this pilot clinical trial was to compare deposition distribution radiolabeled via in healthy adults across three rates delivered active heated humidification, further identify impact without humidity. Methods: Twenty-three (23) (16F) were randomized receive humidification or unheated oxygen...
Abstract Background Different types of nebulizers, interfaces, and flow rates are used to deliver aerosolized medications children. The purpose this study was determine the effect nebulizer type, delivery interface, rate on aerosol drug spontaneously breathing pediatric infant lung models. Methodology A teaching mannequin attached a sinusoidal pump via collecting filter at bronchi simulate child (Vt: 250 mL, RR: 20 bpm Ti: 1 second) (Vt = 100 RR 30 bpm, 0.7 seconds). Albuterol sulfate...
<h3>BACKGROUND:</h3> Previous research reporting factors influencing aerosol delivery in intubated patients has been largely focused on the endotracheal tube (ETT) during mechanical ventilation, with little comparative analysis of effect types artificial airways and their interfaces spontaneous breathing. The purpose this study was to compare via tracheostomy (TT) ETT, using such as T-piece, collar, manual resuscitation bag. <h3>METHODS:</h3> A teaching manikin either an ETT (8.0 mm inner...