- Head and Neck Cancer Studies
- Diverticular Disease and Complications
- Appendicitis Diagnosis and Management
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Intraperitoneal and Appendiceal Malignancies
- Gastrointestinal disorders and treatments
- Oral and Maxillofacial Pathology
- Esophageal and GI Pathology
- Pelvic and Acetabular Injuries
- Thyroid and Parathyroid Surgery
- Soft tissue tumor case studies
- Bariatric Surgery and Outcomes
- Reconstructive Surgery and Microvascular Techniques
- Hernia repair and management
- Tumors and Oncological Cases
- Thyroid Cancer Diagnosis and Treatment
- Enhanced Recovery After Surgery
- Gastroesophageal reflux and treatments
- Cancer-related molecular mechanisms research
- Parathyroid Disorders and Treatments
- Esophageal Cancer Research and Treatment
- Sarcoma Diagnosis and Treatment
- Body Contouring and Surgery
- Ear and Head Tumors
Hospital Alemán
2018-2025
Western University
2022-2025
London Health Sciences Centre
2022-2025
King Saud University
2023
Lawson Health Research Institute
2023
Victoria Hospital
2022
University of Buenos Aires
2019-2020
BackgroundThere is significant interest in treatment de-escalation for human papillomavirus-associated (HPV+) oropharyngeal squamous cell carcinoma (OPSCC) patients given the generally favourable prognosis. However, 15–30% of recur after primary treatment, reflecting a need improved risk-stratification tools. We sought to develop molecular test risk stratify HPV+ OPSCC patients.MethodsWe created an immune score (UWO3) associated with survival outcomes six independent cohorts comprising 906...
Squamous cell carcinoma is the most common malignancy of oral cavity. Primary treatment involves surgical resection tumour with a surrounding margin. Historically, commonly accepted margin clearance 5 mm. This distance controversial, recent publications suggesting closer margins do not impact local recurrence and survival. The objective this study to determine closest that does overall survival.A retrospective review London Health Sciences Centre Head Neck Multidisciplinary Clinic between...
Objectives: Cancers of the maxillary region are often treated surgically with a maxillectomy followed by rehabilitation involving surgical reconstruction or obturator insertion to improve functional outcomes. However, there is lack consensus regarding specific indications for either method. The objective this study was identify unique domains patients who underwent post-op provide standardized data that can inform selection Methods: This mixed-methods qualitative research conducted from...
Patients with head and neck squamous cell cancer (HNSCC) are at a greater risk of developing pulmonary metastases and/or second primary lung cancer. However, it remains uncertain whether screening in these patients, when the initial staging studies negative, confers any survival benefit. To evaluate long-term outcomes patients HNSCC undergoing chest radiography vs low-dose computed tomography for metastasis This randomized parallel trial was conducted large academic hospital Canada enrolling...
NUT midline carcinomas are rare, aggressive, and poorly differentiated tumors that must be considered in the differential diagnosis of head neck tumors. Despite scarce data, proton therapy could an option for some patients.
The objective of this study was to examine the utility postoperative radiation for low and intermediate grade cancers parotid submandibular glands.The authors conducted a retrospective, Canadian-led, international, multi-institutional analysis patient cohort with or salivary gland cancer who were treated from 2010 until 2020 without therapy. A multivariable, marginal Cox proportional hazards regression performed quantify association between locoregional recurrence (LRR) receipt therapy while...
Neck carcinoma of unknown primary (CUP) is a frequent scenario. Transoral robotic mucosectomies (TORM) pharynx have increased rate identification, but come with cost treatment delay.We reviewed patients who underwent CUP protocol from 2014 to 2020. Patients cervical nodes and failure localize source were classified as CUP. We determined identification postoperative complications.We included 65 TORM. Surgical approach consisted lingual and/or palatine tonsillectomies. The detection was 49.2%....
Background: Laparoscopic Roux-en-Y gastric bypass (RYGB) is one of the most common procedures to treat morbid obesity. Abdominal drains are often placed during operation detect complications earlier. The aim this study was assess benefit routine drain placement laparoscopic RYGB. Materials and Methods: A consecutive series patients undergoing RYGB between 2017 2018 analyzed. sample randomized before procedure into two groups: with abdominal (G1) without (G2). Patients intraoperative were...
Gallstone ileus is a rare entity, and an obstructing gallstone in the left colon even less frequent. A 78-year-old man was evaluated for abdominal distension pain, associated with lack of bowel movements past 5 days. An computed tomography showed cholecystocolonic fistula descending colon. During operation, retrieved through longitudinal colotomy proximal to impaction site, which then closed.
Airway fires are a rare but devastating complication of airway surgery. Although protocols for managing have been discussed, the ideal conditions igniting remain unclear. This study examined oxygen level required to ignite fire during tracheostomy.Porcine Model.Laboratory.Porcine tracheas were intubated with 7.5 air-filled polyvinyl endotracheal tube. A tracheostomy was performed. Monopolar and bipolar cautery used in independent experiments assess ignition capacity. Seven trials performed...
Abstract Background We aimed to analyze and compare the timing patterns of treatment failure, survival after progression between HPV‐positive (HPV+) HPV‐negative (HPV−) patients undergoing chemoradiation for oropharyngeal squamous cell carcinomas (OPSCC). Methods A retrospective review was performed all primary OPSCC 2008 2021. Demographic clinical data were collected. Kaplan–Meier estimates overall (OS), time recurrence/metastases (TTR) compared using log‐rank test, with Cox regression used...
: Changes in healthcare system, such as implementation of working hours' restrictions residency programs, and ethical patient's security regulations, have modified the methods available time for trainee's education. These restrictions, motivated creation novel teaching tools a complete successful Currently, simulation is one most implemented globally. Fortunately, different models been developed: Virtual simulation, living animals, human animal cadavers, box-training 3D printed artificial...