Andrew Leung

ORCID: 0000-0003-3349-1574
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About
Contact & Profiles
Research Areas
  • Cerebrovascular and Carotid Artery Diseases
  • Head and Neck Cancer Studies
  • Brain Metastases and Treatment
  • Acute Ischemic Stroke Management
  • Neurosurgical Procedures and Complications
  • Glioma Diagnosis and Treatment
  • Spinal Fractures and Fixation Techniques
  • Medical Imaging and Analysis
  • Radiology practices and education
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Head and Neck Surgical Oncology
  • Radiation Dose and Imaging
  • Intracranial Aneurysms: Treatment and Complications
  • Radiomics and Machine Learning in Medical Imaging
  • Cerebral Venous Sinus Thrombosis
  • Venous Thromboembolism Diagnosis and Management
  • Advanced MRI Techniques and Applications
  • CNS Lymphoma Diagnosis and Treatment
  • Spine and Intervertebral Disc Pathology
  • Neurological Complications and Syndromes
  • Tracheal and airway disorders
  • Salivary Gland Tumors Diagnosis and Treatment
  • Advanced X-ray and CT Imaging
  • Spinal Hematomas and Complications
  • Ear and Head Tumors

Western University
2016-2025

London Health Sciences Centre
2010-2025

Victoria Hospital
2020-2024

Deleted Institution
2023

Emory University
2018

Health Care Foundation
2018

Alberta Bible College
2015

Cognitive Neuroimaging Lab
2015

Tuen Mun Hospital
2015

University Hospital
2012

Between Gadolinium Contrast Exposure and the Risk of ParkinsonismGadolinium-based contrast agents are used for enhancement during magnetic resonance imaging (MRI).Safety concerns have emerged over retained gadolinium in globus pallidi. 1,2Neurotoxic effects been seen animals when is given intrathecally humans. 1 In July 2015, US Food Drug Administration stated that it was unknown whether deposits were harmful.The substantia nigra (affected Parkinson disease) directs voluntary movement via...

10.1001/jama.2016.8096 article EN JAMA 2016-07-05

10.1016/s0891-5245(03)00212-8 article EN Journal of Pediatric Health Care 2004-01-01

To conduct a comprehensive assessment of shoulder and neck function following the pectoralis major pedicled flap (PMPF) for head reconstruction.Case-control study.The study group consisted laryngectomized patients who underwent PMPF control those standard laryngectomy. Bilateral quantitative measurements strength range motion (ROM) ROM by blinded physiotherapist subjective quality-of-life using Shoulder Pain Disability Index (SPADI) Neck (NDI) questionnaires were collected. Lateral cervical...

10.1002/lary.20900 article EN The Laryngoscope 2010-05-12

Hemodynamic instability may complicate carotid angioplasty and stenting in up to 40% of patients. The authors have previously demonstrated that primary self-expanding stent placement alone can gradually dilate severely stenosed arteries without the use balloons. hypothesized eliminating balloon would reduce baroreceptor stimulation, thereby decreasing incidence hemodynamic instability.Ninety-seven high surgical risk patients with symptomatic, were treated intention using a alone....

10.3171/2008.9.jns08509 article EN Journal of neurosurgery 2009-02-20

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10.1017/cjn.2025.1 article EN Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2025-01-10

Background and Purpose— The hyperdense middle cerebral artery sign (HMCAS) is a well-established marker of early ischemia on noncontrast computed tomography the brain (NCCT). Recently MCA dot has been described proposed to indicate thrombosis M2 or M3 branches. purpose this study was define ICA (HICAS) determine its prevalence, diagnostic prognostic value, reliability as for ischemia. Methods— Noncontrast scans 71 patients with acute ischemic stroke were analyzed presence HICAS, HMCAS, sign....

10.1161/strokeaha.107.505230 article EN Stroke 2008-05-04

<b>BACKGROUND AND PURPOSE:</b> Cervical internal carotid artery (ICA) occlusion with middle cerebral (MCA) embolic is associated a low rate of recanalization and poor outcome after intravenous thrombolysis. Prompt revascularization required to prevent disabling stroke. We report our experience on acute ischemic stroke patients tandem ICA or MCA occlusions treated microcathether navigation intra-arterial thrombolysis by use collateral pathways including the posterior anterior communicating...

10.3174/ajnr.a1163 article EN cc-by American Journal of Neuroradiology 2008-06-04

Object Conventional endovascular therapy for carotid stenosis involves placement of an embolic protection device followed by stent insertion and angioplasty. A simpler approach may be a alone. The authors determined how often this could used to treat patients with stenosis, assessed which factors would preclude approach. Methods Over period 6 years, 97 symptomatic were treated the intention using “stent-only” Arteries in 77 (79%) stents alone, 13 required preinsertion balloon dilation,...

10.3171/jns/2008/109/9/0454 article EN Journal of neurosurgery 2008-08-29

Machine learning (ML) has been used to predict tumor progression post-stereotactic radiosurgery (SRS) based on pre-treatment MRI for brain metastasis (BM) patients, but there is variability in the definition of what constitutes progression. We aim measure magnitude change performance an ML model predicting post-SRS when various definitions were used. collected pre- and contrast-enhanced T1-weighted scans from 62 BM patients ( n=115 BMs). trained a random decision forest using radiomic...

10.1117/1.jmi.12.2.024504 article EN Journal of Medical Imaging 2025-04-08

To prospectively determine the prevalence and clinical importance of extraspinal abnormalities in adult outpatients undergoing computed tomography (CT) lumbar spine.Institutional review board approval was obtained for this prospective study. Informed consent from 400 consecutive (mean age, 49 years; 212 male 188 female patients) spine CT low back pain and/or radiculopathy. Those with known malignancy were excluded. Dedicated spinal abdominal full-field-of-view (FOV) images each patient...

10.1148/radiol.12112152 article EN Radiology 2012-03-23

A 61-year-old right-handed man presented with a two-day history of new headache that had developed gradually several hours after he dived into lake. The headache, which encompassed the entire left side head, maximal intensity 10 out and was described as dull constant

10.1503/cmaj.091261 article EN cc-by-nc-nd Canadian Medical Association Journal 2010-04-12

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10.1017/s0317167100015031 article EN Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2013-09-01

Abstract Introduction: The Circle of Willis (CoW) is the most effective collateral circulation to brain during internal carotid artery (ICA) occlusion. Carotid stump pressure (CSP) an established surrogate measure cerebral circulation. This study aims use hemodynamic and computed tomography angiography measurements determine strongest influences upon dependent variable, CSP. These findings could help clinicians noninvasively assess adequacy facilitate surgical risk assessment in outpatient...

10.1017/cjn.2016.10 article EN Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2016-03-31

Importance The association of primary tumor volume with outcomes in T3 glottic cancers treated radiotherapy concurrent chemotherapy remains unclear, some evidence suggesting worse locoregional control larger tumors. Objective To evaluate the oncologic patients N0-N3 M0 cancer (chemo)radiotherapy a large multi-institutional study. Design, Setting, and Participants This retrospective cohort study involved 7 Canadian centers from 2002 to 2018. Tumor was measured by expert neuroradiologists on...

10.1001/jamaoto.2022.3996 article EN JAMA Otolaryngology–Head & Neck Surgery 2022-12-08
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