A5038892854- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Cardiovascular Health and Disease Prevention
- Acute Ischemic Stroke Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- Aortic aneurysm repair treatments
- Cerebral Venous Sinus Thrombosis
- Meningioma and schwannoma management
- Aortic Disease and Treatment Approaches
- Cerebrospinal fluid and hydrocephalus
- Spinal Hematomas and Complications
- Head and Neck Surgical Oncology
- Coronary Interventions and Diagnostics
- History of Medical Practice
- Spine and Intervertebral Disc Pathology
- Congenital Heart Disease Studies
- Surgical Simulation and Training
- Cervical and Thoracic Myelopathy
- Thermal Regulation in Medicine
- Optical Imaging and Spectroscopy Techniques
- Moyamoya disease diagnosis and treatment
- Cerebrovascular and genetic disorders
Western University
2014-2024
Dalhousie University
2021-2024
London Health Sciences Centre
2011-2020
Institute of Neurological Sciences
2011-2019
Neurological Surgery
2017
University of Tennessee Health Science Center
2017
Hamilton Health Sciences
2016
McMaster University
2016
University Hospital
1995-2015
Western University of Health Sciences
2014
Carotid endarterectomy clearly benefits patients with symptomatic severe stenosis (SCS), but the risk of stroke is so low for asymptomatic (ACS) that number needed to treat very high. We studied transcranial Doppler (TCD) embolus detection as a method identifying at higher who would have lower treat.Patients carotid > or =60% by ultrasound had never been (81%) least 18 months (19%) were TCD up 1 hour on 2 occasions week apart; followed years.319 studied, age (standard deviation) 69.68 (9.12)...
Computational fluid dynamics (CFD) modeling of nominally patient-specific cerebral aneurysms is increasingly being used as a research tool to further understand the development, prognosis, and treatment brain aneurysms. We have previously developed virtual angiography indirectly validate CFD-predicted gross flow against routinely acquired digital subtraction angiograms. Toward more direct validation, here we compare detailed, velocity fields those measured using particle imaging velocimetry...
It has recently become possible to simulate aneurysmal blood flow dynamics in a patient-specific manner via the coupling of three-dimensional (3-D) X-ray angiography and computational fluid (CFD). Before such image-based CFD models can be used predictive capacity, however, it must shown that they indeed reproduce vivo hemodynamic environment. Motivated by fact there are currently no techniques for adequately measuring complex velocity fields vivo, this paper we describe how cine angiograms...
Background Total body hypothermia is an established neuroprotectant in global cerebral ischemia. The role of acute ischemic stroke remains uncertain. Selective application to a region focal ischemia may provide similar protection with more rapid cooling and elimination systemic side effects. We studied the effect selective endovascular model adult domestic swine. Methods After craniotomy under general anesthesia, proximal middle artery branch was occluded for 3 h, followed by h reperfusion....
✓ Historically, the neurosurgical treatment of large acoustic neurinomas has developed with two principal goals: complete tumor removal and preservation facial nerve function. A recent goal for small tumors is hearing. Out a personal series 124 treated over past 35 years, senior author undertaken radical intracapsular approach in 12 patients (> 3 cm diameter). Surgical indications included advanced age (five cases), patient's wish to avoid any risk paralysis (six contralateral palsy (one...
From the Division of Neurosurgery, Department Clinical Neurological Sciences, The University Western Ontario and Hospital, London, Ontario, Canada
The authors report their results in a series of large or giant carotid ophthalmic segment aneurysms clipped using retrograde suction decompression.A retrospective review clinical data and treatment summaries was performed for 18 patients with artery managed operatively via decompression. Visual outcomes, Glasgow Outcome Scale (GOS) scores, operative complications were determined. Postoperative angiography assessed.During 17-year period, underwent surgery mean aneurysm size 26 mm. Three...
Object. The authors report on important factors that influenced clinical and angiographically demonstrated outcomes in patients treated using coil embolization. Methods. This study included 160 consecutive who underwent endovascular embolization for treatment of intracranial aneurysms. Univariate multivariate logistic regression analyses were performed to assess the immediate posttreatment angiographic result. Cox analysis was used establish related occurrence negative events as well a curve...
OBJECTIVE The aim of this study was to present the clinical and radiological characteristics, surgical management, outcome in a large series patients with aneurysms distal anterior cerebral artery (DACA) managed microsurgical era. METHODS records 1109 circulation at authors' institution between 1970 1998 were reviewed. RESULTS Fifty-nine (5.3%) identified 67 DACA aneurysms. Seventy-three percent women. mean age all 47 years. Multiple 51% patients, most commonly on middle artery. Thirty-six...
Hemodynamic instability may complicate carotid angioplasty and stenting in up to 40% of patients. The authors have previously demonstrated that primary self-expanding stent placement alone can gradually dilate severely stenosed arteries without the use balloons. hypothesized eliminating balloon would reduce baroreceptor stimulation, thereby decreasing incidence hemodynamic instability.Ninety-seven high surgical risk patients with symptomatic, were treated intention using a alone....
Object Conventional endovascular therapy for carotid stenosis involves placement of an embolic protection device followed by stent insertion and angioplasty. A simpler approach may be a alone. The authors determined how often this could used to treat patients with stenosis, assessed which factors would preclude approach. Methods Over period 6 years, 97 symptomatic were treated the intention using “stent-only” Arteries in 77 (79%) stents alone, 13 required preinsertion balloon dilation,...