About
Contact & Profiles
A5016976472
Research Areas
- ATP Synthase and ATPases Research
- Metabolomics and Mass Spectrometry Studies
- Alzheimer's disease research and treatments
- Cancer, Hypoxia, and Metabolism
- Mitochondrial Function and Pathology
- Tryptophan and brain disorders
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2024
Abstract In the ALDH2 rs671 variant, a guanine changes to an adenine, resulting in dramatic decrease catalytic activity of enzyme. Population-based data are contradictory about whether this variant increases risk Alzheimer’s disease. East Asian populations, prevalence is 30–50%, making National Human Brain Bank for Development and Function (the largest brain bank Asia) important resource explore link between polymorphism disease pathology. Here, using 469 postmortem brains, we find that...
10.1038/s41467-024-46899-0
article
EN
cc-by
Nature Communications
2024-03-22
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